APTT Activated Partial Thromboplastin Time Test in Ahmednagar - Metropolis Healthcare
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APTT Activated Partial Thromboplastin Time Test in Ahmednagar



A PTT test enables doctors to examine your body’s ability to form blood clots.

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    It should be measured to investigate a bleeding or thrombotic episode. It helps evaluate the risk of excessive bleeding prior to a surgical procedure. Also, to monitor heparin anticoagulant therapy.

Your health practitioner may recommend this test for you if you show symptoms of prolonged and excessive bleeding which includes:

  • Frequent nosebleeds
  • Blood in urine
  • Heavy menstruation for women
  • Painful and swollen joints
  • Easy bruising

The activated partial thromboplastin time is a functional measure of the intrinsic and usual pathways of the clotting cascade. To form blood clots, to seal off injuries, to blood vessels and tissue, to restrict further blood loss, and to give the damaged areas time to seal the body using the coagulation cascade. The cascade contains a group of clotting factors. These proteins are activated serially along either the extrinsic or intrinsic pathways.

The branches then come together into the common pathway, and complete their task with the formation of a steady blood clot. These three pathways have to work when a person starts bleeding. Each component of the coagulation cascade must be working properly and be present in enough quantity for normal blood formation. Stable clot formation will be inhibited and excessive bleeding and/or clotting may occur if there is an inherited or assimilated deficiency in one or more of the factors, or if the factors are functioning unusually. The test measures the amount of time that it takes for clotting to happen when reagents are added to plasma in a test tube.

Reference Values Of APTT Activated Partial Thromboplastin Time Test

APTT test results are calculated in seconds. Normal results are typically 25 to 35 seconds which means that it took your blood sample 25 to 35 seconds to clot after adding the chemicals.


Normal aPTT may reflect normal clotting function but moderate single factor deficiencies might exist. They will not be reflected in aPTT until they are decreased by 30 to 40% of normal. Also, some lupus anticoagulants can also be present which will not prolong the regular aPTT result. If a lupus anticoagulant (LA) is suspected, an LA-sensitive aPTT may be used to test for it, or a like test called the dilute Russell Viper venom test (DRVVT).

A prolonged aPTT usually depicts that clotting is taking longer to occur than expected (but is related to increased risk of blood clots because of a lupus anticoagulant)

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APTT Activated Partial Thromboplastin Time Test