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Dual marker test is a screening blood test that is used to screen pregnant women for potential congenital defects in foetus i.e., neural tube defects, Down syndrome and Trisomy 18 in the unborn child. Primarily two components are measured in mother’s blood (thus known as the Dual Marker test). This test can be performed any time between 8 to 13.6 weeks of pregnancy.
WRITTEN BY: Dr.Shibani R Medical Writer, Medical Affairs
Pregascreen Dual Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Pregascreen Dual with a clear pricing structure.
The Pregascreen Dual Price in Mumbai is ₹ 3,500 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
Why take Serum Dual Marker Maternal screening test reflex Confirmation by either NIPT or Karyotyping/FISH of CVS) Test?
A dual Marker Test is given to pregnant women to determine any chromosomal malformation in the foetus. This test screens for Down Syndrome, Patau Syndrome and Edward Syndrome in the developing fetus using maternal blood as the sample.
This test is for pregnant females in their 8 to 13.6 weeks of pregnancy.
More Info on Serum Dual Marker Maternal screening test reflex Confirmation by either NIPT or Karyotyping/FISH of CVS) Test
This includes Dual marker - PAPP-A and Free Beta HCG. If high risk aneuploidy is reported, then either NIPS or Karyotyping-FISH of amniotic fluid/CVS is done at no additional cost. Recommended at (gestational age) :8 to 13.6 weeks.
What does Serum Dual Marker Maternal screening test reflex Confirmation by either NIPT or Karyotyping/FISH of CVS) Test measure?
It measures the levels of PAPPa & Free HCG in the maternal blood. NIPT (Screening) or Karyotyping and FISH of amniotic fluid (Any one) is used for confirmation of screen positives with consent.
Why is Serum Dual Marker Maternal screening test reflex Confirmation by either NIPT or Karyotyping/FISH of CVS) Test done?
This dual screen test is used to screen genetic disorders and other abnormalities in the foetus. It is very important to know that this is a SCREENING test and a positive (high risk) result does not confirm a defect. Further confirmatory tests should be done to reach a conclusion. A reflex test for NIPT (Screening) or Karyotyping and FISH of amniotic fluid (Any one) is used for confirmation of screen positives with consent.
What to expect during Serum Dual Marker Maternal screening test reflex Confirmation by either NIPT or Karyotyping/FISH of CVS) Test?
The test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.
High HCG level indicates multiple pregnancies. Low levels of HCG indicate a miscarriage or ectopic pregnancy.
Abnormal PAPPa levels may indicate high risk pregnancies. Further tests post consultation with the gynaecologist may be required.
Combined risk is calculated using biochemical values as well as sonography finding such as NT values, soft markers etc.
Abnormal test (high risk pregnancy) result does not always indicate a birth defect; it might be because of a variation in the estimated gestational age or other factors. A more specific screening test (NIPT) or Genetic screening from Maternal blood for aneuploidies – Trisomy 21, 13, 18 may be required.
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