AANA by ELISAAnti Nuclear Antibody screening Serum

ANA by ELISA Anti Nuclear Antibody Screening is a screening test done to aid diagnosis of autoimmune disorders. Many auto immune disorder have common signs and symptoms — joint pain, fatigue and fever, some have renal and dermatological involvement. While an ANA test can't confirm a specific diagnosis, it can rule out some diseases. ANA blot or monospecific ELISA tests are recommended for further confirmation and more specific diagnosis. Depending on the autoantibodies present against the specific antigen, the type of autoimmune disorder can be diagnosed by clinical correlation.

The blood test measures the presence of Anti nuclear antibodies by ELISA technique.

The blood sample is taken from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

ANA positive result: Further tests for the presence of particular antinuclear antibodies, some of which are specific to certain diseases are advised. ANA test is positive in the following autoimmune conditions: systemic autoimmune rheumatic disease particularly systemic lupus erythematosus, Sjogren syndrome, mixed connective tissue disease, discoid lupus erythematosus, drug-induced lupus erythematosus , systemic sclerosis, CREST syndrome (calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, telangiectasia) and idiopathic inflammatory myopathies. Based on the autoantibodies present against the specific antigen, the autoimmune disorder can be diagnosed. ANA negative results do no rule out all autoimmune diseases A positive result doesn't necessarily indicate an autoimmune disease, many women older than 6, some infectious diseases, cancers, certain drugs have been associated with antinuclear antibodies.