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Activated Partial Thromboplastin Time APTT Test

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APTT Test Overview

APTT test enables doctors to examine your body’s ability to form blood clots.

APTT is a coagulation test that measures the time taken to form a blood clot. In case of an injury causing bleeding , the proteins in blood form a coagulation pathway or cascade to stop the bleeding by forming clots. The activated partial thromboplastin time (APTT) test measures the functionality of the intrinsic and common pathways of the coagulation cascade. (Factor XII, XI, IX, VIII, X, V, II and Fibrinogen).

WRITTEN BY: Dr.Shibani R Medical Writer, Medical Affairs

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Activated Partial Thromboplastin Time APTT Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Activated Partial Thromboplastin Time APTT Test with a clear pricing structure.

The Activated Partial Thromboplastin Time APTT Test Price in Mumbai is ₹ 610 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

APTT test measured to investigate a bleeding or thrombotic episode. It helps evaluate the risk of excessive bleeding prior to a surgical procedure. Also, to monitor heparin anticoagulant therapy.

Your health practitioner may recommend aptt test for you if you show symptoms of prolonged and excessive bleeding which includes:

  • Frequent nosebleeds
  • Blood in urine
  • Heavy menstruation for women
  • Painful and swollen joints
  • Easy bruising

The activated partial thromboplastin time is a functional measure of the intrinsic and usual pathways of the clotting cascade. To form blood clots, to seal off injuries, to blood vessels and tissue, to restrict further blood loss, and to give the damaged areas time to seal the body using the coagulation cascade. The cascade contains a group of clotting factors. These proteins are activated serially along either the extrinsic or intrinsic pathways.

The branches then come together into the common pathway, and complete their task with the formation of a steady blood clot. These three pathways have to work when a person starts bleeding. Each component of the coagulation cascade must be working properly and be present in enough quantity for normal blood formation. Stable clot formation will be inhibited and excessive bleeding and/or clotting may occur if there is an inherited or assimilated deficiency in one or more of the factors, or if the factors are functioning unusually. The aptt test measures the amount of time that it takes for clotting to happen when reagents are added to plasma in a test tube.

The test is required in cases of : 
- Suspected problems with 1 or more clotting factors. 
-Bleeding disorders, such as von Willebrand disease or another disease that prevents your blood from clotting.
-To monitor people who are getting heparin therapy. Heparin is a blood thinner used to prevent dangerous blood clots. 

The test calculates the APTT in the blood. 

The test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer. 

Prolonged APTT tests may be due to inherited or acquired factor deficiencies,  lupus anticoagulant (LA), DIC, fibrinolysis, cirrhosis, malabsorption, and liver diseases. APTT levels may also be affected in patients on anti-coagulant therapy. 

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