Prolactin Test
Also known as: Prolactin Test (PRL)
Prolactin Test (PRL) Details in Brief
| Also Known As | PRL Test, Prolactin Serum Test |
|---|---|
| Purpose | Measures prolactin hormone levels in blood, helps diagnose hyperprolactinemia, supports evaluation of pituitary disorders, and aids in infertility and menstrual irregularity assessments. |
| Preparation | Blood collected 2-3 hours after waking up. Avoid stress and strenuous exercise. Rest for 30 minutes before blood collection. High biotin doses (>5 mg/day) should be avoided for at least 8 hours before blood collection. |
| Fasting | Not mandatory |
| Reporting Time | After 6 hours |
| Cost | 650 |
What Is a Prolactin Test?
A prolactin test, also known as a PRL test, is a simple blood test that measures the level of prolactin hormone in your bloodstream. Prolactin is produced by your pituitary gland, a small but important gland located at the base of your brain.
The test uses a blood sample drawn from a vein in your arm. This test helps detect conditions related to abnormal prolactin levels, which can affect your reproductive health and indicate potential pituitary gland disorders.
What Does the Prolactin Test Measure?
The prolactin test measures the concentration of prolactin hormone in your blood to help doctors understand your hormonal health:
- Investigate irregular or absent menstrual periods in women.
- Determines potential causes of infertility in both men and women.
- Identifies the reason for unexpected milk discharge from breasts when not pregnant or breastfeeding.
- Diagnoses and monitors prolactinoma (a non-cancerous pituitary tumour).
- Evaluates symptoms like low sex drive or erectile dysfunction in men.
- Monitors treatment effectiveness for prolactin-related conditions.
Prolactin Test: Who Needs It and Why It's Done
What Symptoms May Call for a Prolactin Test?
Your doctor may recommend a PRL test if you experience certain symptoms that vary between men and women:
For Women:
- Irregular or missed menstrual periods
- Difficulty getting pregnant
- Unexpected milk discharge from breasts
- Breast tenderness
- Vaginal dryness
- Unexplained acne or excessive facial hair
For Men:
- Decreased sex drive
- Difficulty with erections
- Breast tissue enlargement
- Fertility problems
- Rare cases of milk discharge from the breasts
For Both:
- Persistent headaches
- Vision problems
Who Should Get a Prolactin Test?
Several groups of people may benefit from this test:
- Individuals experiencing the symptoms mentioned above.
- Patients with known pituitary gland disorders requiring monitoring
- People taking certain medications that can affect prolactin levels.
- Women with unexplained infertility or menstrual irregularities.
- Men with sexual health concerns or fertility issues.
Why Is a Prolactin Test Done?
The PRL test serves as a crucial diagnostic tool to identify hormonal imbalances affecting reproductive health and helps doctors diagnose conditions like pituitary tumours, guiding appropriate treatment decisions.
Importance of a Prolactin Test
The prolactin test plays a vital role in women's and men's health by identifying treatable causes of fertility and reproductive issues. High prolactin levels are a common yet manageable cause of infertility, making early detection essential for successful treatment. This test directly helps diagnose prolactinoma, the most common hormone-producing pituitary tumour.
Early identification allows timely treatment that can restore fertility, regulate menstrual cycles, and relieve symptoms like headaches or vision changes. Prolactin test results guide treatment plans and help monitor how well medications are working, ensuring you receive the most effective care for your specific condition.
Prolactin Test Booking & Reports – Metropolis Healthcare
How to Book a Prolactin Test?
- Simple Online Booking
You can book the test through the Metropolis Healthcare App or website. Select 'Prolactin Test', choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab. - Safe Home Sample Collection
Our trained phlebotomists ensure the timely collection of your sample while strictly following all safety and hygiene protocols. - Sample Tracking Updates
Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website. - Accurate Laboratory Testing
Your sample is processed at our NABL- & CAP-accredited laboratories, where expert technicians ensure accurate results. - Quick & Easy Reports
Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is Home Sample Collection for the Prolactin Test Available Near You?
Yes, home sample collection for prolactin testing is available at Metropolis Healthcare, eliminating the need for travel and waiting times at labs. With strict adherence to safety protocols and proper sample handling, our trained and certified phlebotomists maintain the same accuracy standards as lab visits. Our commitment to accessible testing means reliable results and quality care, wherever you are.
How Long Does It Take to Get a Prolactin Test Report?
Reports are usually available within 6 hours after the sample reaches the lab.
Where Can I See or Get the Prolactin Test Results?
Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.
Interpreting Prolactin Test Results
What Your Prolactin Test Results May Indicate
The table below shows the reference ranges for prolactin levels and what different values might indicate for your health:
|
Parameter |
Reference Range |
High Values May Indicate |
Low Values May Indicate |
|
Prolactin |
4.79-23.3 ng/mL
|
Prolactinoma, hypothyroidism, kidney disease, liver disease, polycystic ovary syndrome, other pituitary disorders, anorexia nervosa |
Low prolactin levels may occur in hypopituitarism or dopamine agonist therapy; isolated low levels are usually not clinically significant. |
Conditions that May Affect Prolactin Test Accuracy
Several factors can influence your prolactin test results and should be discussed with your doctor:
- Certain medications, particularly antipsychotics, antidepressants, and blood pressure medicines, can raise prolactin levels.
- Physical or emotional stress can temporarily increase prolactin.
- Strenuous exercise within 24 hours before the test may affect results.
- High-dose biotin supplements (>5 mg/day) can interfere with certain immunoassay methods such as ECLIA; avoid for at least 8 hours before testing.
- Pregnancy and breastfeeding naturally elevate prolactin levels.
- Prolactin levels show a diurnal pattern—highest during sleep and early morning—so blood collection should ideally be done 2–3 hours after waking.
How Is a Prolactin Test Done?
The prolactin test follows a standard blood collection procedure that is quick and straightforward:
- A healthcare professional cleans the area on your arm with an antiseptic.
- An elastic band is tied around your upper arm to make the veins more visible.
- A small needle is inserted into a vein, usually in your elbow area.
- A small amount of blood is collected into a special tube.
- The needle is removed, and a cotton ball or bandage is applied to prevent bleeding.
- Your blood sample is sent to the laboratory for analysis using advanced testing methods.
How Should You Prepare for a Prolactin Test?
Proper preparation helps ensure accurate test results:
- Schedule your test 2–3 hours after waking for optimal timing.
- Avoid strenuous exercise and stressful situations for 24 hours before the test.
- Rest for 30 minutes before your blood collection.
- Avoid high-dose biotin supplements (>5 mg/day) for at least 8 hours before the test.
- Inform your doctor about all medications you're taking, as some can affect prolactin levels.
- No special diet restrictions are needed for this test.
Diseases that a Prolactin Test Can Help Detect
The prolactin test can help identify several important health conditions:
- Prolactinoma (non-cancerous pituitary tumour)
- Hyperprolactinaemia (elevated prolactin levels)
- Hypothyroidism (underactive thyroid)
- Polycystic ovary syndrome (PCOS)
- Pituitary gland disorders
- Chronic kidney disease (CKD), which can reduce prolactin clearance and raise levels
- Chronic liver disease may increase prolactin levels due to altered metabolism and clearance
- Hypothalamic disorders
Prolactin Tests/Packages that You Can Book With Metropolis Healthcare
The following table shows related tests and packages available at Metropolis Healthcare for comprehensive hormonal assessment:
|
Test/Package Name |
Purpose/Highlights |
|
Comprehensive reproductive hormone panel for fertility evaluation. |
|
|
Complete hormonal profile for men's reproductive health assessment. |
|
|
Multiple sample collection for accurate prolactin level assessment. |
Prolactin Test Prices in Different Cities
The cost of a prolactin test may vary depending on your location. Here's a table showing the approximate prices in different cities.
|
City |
Price (INR) |
|
₹450 - ₹ 660 |
|
|
₹450 - ₹ 660 |
|
|
₹450 - ₹ 660 |
|
|
₹450 - ₹ 660 |
|
|
₹450 - ₹ 660 |
|
|
₹450 - ₹ 660 |
References :
Arch Pathol Lab Med—Vol141, November 2017.
Prolactin Test (PRL) Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Prolactin Test (PRL) with a clear pricing structure.
The Prolactin Test (PRL) Price in Mumbai is ₹ 650.
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
The optimal collection time is in the morning, about 2–3 hours after waking, when prolactin levels are physiologically stable. They are highest during sleep and immediately upon waking.
Fasting is not mandatory for the prolactin test. You can eat and drink normally before the test, though avoiding heavy meals immediately beforehand may be beneficial.
Hydration status has minimal impact on prolactin levels but good hydration facilitates smooth venipuncture. However, staying well-hydrated before any blood test makes the collection process easier and more comfortable for you.
No special diet is required. However, inform your doctor about all medications you're taking, as some can affect prolactin levels. Avoid high biotin doses (> 5 mg/day) for at least 8 hours before blood collection.
A healthcare professional cleans your arm, ties an elastic band around it, inserts a small needle into a vein, collects blood into a tube, and applies a bandage.
The risks are minimal and similar to any blood test: slight pain at the needle site, minor bruising, or feeling lightheaded. Serious complications are extremely rare.
Normal serum prolactin levels (ECLIA): 4.79–23.3 ng/mL (non-pregnant adults). During pregnancy, levels progressively rise—First trimester: 9.95–101 ng/mL; Second: 17.2–270 ng/mL; Third: 67.9–419 ng/mL.
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