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Serum Creatinine Test

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Creatinine Test Overview

A creatinine blood test determines the amount of creatinine in the blood. When the creatine in your muscles breaks down, creatinine is created as a waste product. Your blood's creatinine levels can tell your doctor how well your kidneys are functioning.

Nephrons, which are tiny blood-filtering units, are found in abundance in each kidney. The glomeruli, a small group of blood arteries, are continuously filtered by the nephrons. These organs cleanse the blood of waste materials, extra water, and other pollutants. Toxins are kept in the bladder until urine is discharged.

What is it used for?

The following conditions may necessitate a creatinine test:

  • If you have any kidney disease symptoms or indicators
  • In case of diabetes or high blood pressure
  • You should get screened for any other illnesses that raise the risk of kidney disease.
  • to track the course or therapy of kidney illness
  • to keep an eye out for drug side effects that could affect kidney function or cause kidney damage
  • to keep an eye on a transplanted kidney's performance

Written by: Dr.Shibani R, Medical Writer, Medical Affairs

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Serum Creatinine Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Serum Creatinine Test with a clear pricing structure.

The Serum Creatinine Test Price in Mumbai is ₹ 250 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

If you exhibit symptoms of renal illness, your doctor can request a creatinine blood test to evaluate your creatinine levels. These signs consist of:

  • exhaustion and difficulty sleeping
  • a decrease in appetite
  • the face, wrists, ankles, or abdomen and swelling
  • an ache in the lower back near the kidneys
  • variations in urine frequency and output
  • blood pressure is high.
  • nausea\vomiting

Numerous diseases or situations can cause kidney issues, including:

  • Glomerulonephritis is an infection of the kidneys caused by damage to the glomeruli
  • pyelonephritis, a bacterial infection of the kidneys
  • prostate disease, such as an enlarged prostate
  • If blood flow to the kidneys is decreased due to kidney stones, diabetes, heart failure, or dehydration
  • death of kidney cells because of drug abuse
  • streptococcal infections like post-streptococcal glomerulonephritis

The serum creatinine level can be used to gauge how rapidly the kidneys can filter blood (glomerular filtration rate).

The serum creatinine count is considered for estimating GFR and other variables, including age and sex. A GFR of less than 60 indicates renal disease. To track the effectiveness of treatment and the course of the condition, scores below 60 may be employed.

The ability of the kidneys to remove creatinine from urine is measured by creatinine clearance.

Typically, the creatinine measurement in a 24-hour urine sample and a serum sample collected simultaneously are used to calculate creatinine clearance.

The creatinine serum test is an important diagnostic tool to:

– To measure creatinine levels

– To assess kidney function

– To diagnose kidney disorder

– To check the side effects of certain drugs on your kidneys

The creatinine blood test is a simple procedure that uses a minimal amount of blood or urine sample.

The process to withdraw a blood sample for a serum creatinine test:

  • The creatinine blood test is a simple procedure that uses a minimal amount of blood. 
  • The inside of the arm is where the blood sample is taken from. 
  • The site is cleaned with an antiseptic.  
  • To make it simple to locate a vein, they put a band around your arm to cause the veins to expand with blood.
  • To take blood, a needle is placed into a vein at a pre-sterilized location on the inside of the arm. 
  • The test is not painful; however, you may feel a slightly prick when the needle is inserted. 
  • The medical professional covers the area where the blood was extracted with a bandage after removing the needle and taking the blood sample.
Precautions for The Test

To prepare for the test, your doctor could advise fasting the night before. You might have to refrain from eating meat for a particular time before the test. If you are consuming any creatine supplement, you must also stop it.

For the urine test, you might need to collect urine for 24 hours in containers the clinic will give for the creatinine urine test.

Are there Any Risks Involved?

A blood test to measure creatinine is a low-risk technique. However, there are a few little concerns, such as:

  • fainting upon seeing blood,
  • feeling dizziness or vertigo,
  • slight soreness or redness at the site of blood collection
  • maybe bruising, minor pain, or an infection that is not so serious

Micromoles of creatinine per litre of blood (micromoles/L) or milligrams of creatinine per decilitre of blood (mg/dL) are used to measure serum creatinine. The serum creatinine normal range is as follows:

  • 0.74 to 1.35 mg/dL (65.4 to 119.3 micromoles/L) for adult males
  • 0.59 to 1.04 mg/dL (52.2 to 91.9 micromoles/L) for adult females

Results below the expected range may indicate impaired kidney function or diseases that reduce blood flow to the kidneys. Low levels of the waste substance creatinine in the body may indicate that the muscles or liver are not functioning as they should.

If your creatinine levels are high, your kidneys may not function properly. An underlying medical issue is indicated if the blood or urine creatinine levels are high.

A Creatinine serum test is done to check kidney function. This is especially done in patients with chronic kidney disease, long-standing diabetes and hypertension. It may also be done as part of a complete metabolic panel to diagnose metabolic disorders. Serum creatinine values are used to calculate eGFR results.

Serum creatinine results are used to calculate GFR (Glomerular Filtration Rate). It is an indicator of kidney function. High serum creatine levels signify poor functioning of the kidneys. Temporarily high levels may also occur due to exercises, side effects of medications, certain diets and pregnancy. Higher levels may be due to:

  • Blockage in the urinary tract
  • Kidney problems, like kidney damage, failure, or infection
  • Dehydration
  • Breakdown of muscle fibres
  • Complications during pregnancy, such as seizures caused by eclampsia or high blood pressure caused by pre-eclampsia

Low creatinine levels may occur due to muscular disorders (loss of muscle bulk), excessive fluid loss and certain medications. Lower levels may be due to:

  • Conditions leading to decreased muscle mass
  • Malnutrition

The doctors may order this test for assessing other conditions like high blood pressure, diabetes, or medicine overdose.

Although there is little risk involved in this blood test, veins and arteries vary in size from one person to another.

Other risks associated with drawing blood from an individual may include:

  • Excess bleeding
  • Feeling lightheaded or fainting
  • Requiring multiple punctures for locating veins
  • Hematoma
  • Infection

The results of the creatinine serum test determine the glomerular filtration rate or GRF. It is the plasma volume that is filtered by the glomerulus in one second. It is used to check if the kidneys are functioning properly or not.

You should inform your doctor about any medicines you are currently taking, both prescription and over-the-counter. You must also inform if you have had any drug allergies. Some drugs, like cimetidine, chemotherapy drugs, and cephalosporin antibiotics, may increase the levels of creatinine. This may impact your test results. Your doctor may consider this when interpreting your lab test results. So it is important to discuss this in detail with your doctor.

Kidney Functions tESTS, Blood urea nitrogen (BUN) test, basic metabolic panel (BMP) or comprehensive metabolic panel (CMP) are linked to creatinine test.

There are certain preparations for a creatinine serum test. Fasting for at least 8 to 12 hours before the test is essential. It is recommended to not take part in any strenuous 24 hours before the test. It is essential to drink plenty of fluids for hydration. You may avoid cooked meat for 24 hours before your test as cooked meat might raise creatinine levels in the body. You should also avoid taking any medications that could interfere with the test results. The medicines that can interfere with your test results include:

  • Cimetidine, famotidine, and ranitidine
  • Antibiotics, like cefoxitin and trimethoprim

Women are often known to have lower creatinine levels than men. This is because women often have fewer muscles. Creatinine level also varies based on the size and muscle mass of an individual.

In general, the normal range of creatinine,

  • For adult men is 0.74 to 1.35 mg/dL
  • For adult women is 0.59 to 1.04 mg/dL
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