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Homocysteine Test

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Homocysteine Test Details in Brief

Also Known As Total Homocysteine, Plasma Total Homocysteine
Purpose Helps assess risk for cardiovascular diseases, supports evaluation of vitamin B12 and folate deficiencies, aids in diagnosing homocystinuria
Preparation Clinical History Required
Fasting Not Required
Reporting Time After 6 Hours
Cost 1,450

What is a Homocysteine Test?

A Homocysteine Test is a simple diagnostic procedure that measures the amount of an amino acid called homocysteine in your blood. This test uses a blood sample drawn from a vein in your arm. The test helps detect deficiencies of essential vitamins like B12, B6, and folic acid, and can also diagnose a rare genetic disorder called homocystinuria.

What does the Homocysteine Test measure?

Vitamin deficiency detection - Identifies deficiencies in vitamin B12, B6, or folic acid that can cause elevated homocysteine levels
Cardiovascular risk assessment - Evaluates your risk for heart disease, stroke, and blood clots
Homocystinuria diagnosis - Helps diagnose this rare genetic disorder, especially in infants and children
Treatment monitoring - Tracks the effectiveness of vitamin supplements and dietary changes in managing high homocysteine levels

Homocysteine Test: Who Needs It and Why It's Done

What Symptoms May Call for a Homocysteine Test?

Your doctor may recommend this test if you experience symptoms that suggest vitamin deficiencies or genetic disorders:

• Persistent weakness and fatigue
• Dizziness or light headedness
• Pale skin or unusual skin colour changes
• Tingling or numbness in your hands, legs, or feet
• Soreness of the mouth and tongue
• Mood changes or memory problems
• Vision problems (in children)
• Developmental delays in children (in children)
• Bone abnormalities or blood clot history (in children)

Who should get a Homocysteine Test?

This test is recommended for specific groups who may benefit from early detection:

Patients with symptoms - Individuals showing signs of vitamin B deficiency or related complications
High-risk individuals - People with family history of premature heart disease without other known risk factors
Infants and children - Newborns or children suspected of having homocystinuria
Vulnerable populations - Elderly individuals, those with malnutrition, kidney disease, or alcoholism
Monitoring patients - Those already diagnosed with high homocysteine levels receiving treatment

Why is a Homocysteine Test done?

A Homocysteine Test helps identify treatable vitamin deficiencies and genetic conditions early. High homocysteine levels can often be corrected with proper vitamin supplements and dietary changes, preventing serious health complications.

Importance of a Homocysteine Test

The Homocysteine Test plays a crucial role in your healthcare journey by enabling targeted treatment and early intervention. When homocysteine levels are elevated due to vitamin deficiencies, simple treatments like folic acid, vitamin B12, or B6 supplements can effectively lower levels and resolve symptoms.

For children, early diagnosis of homocystinuria through this test is critical to prevent serious complications like intellectual disability, blood clots, and skeletal problems. The test also helps doctors assess your overall cardiovascular risk profile, leading to better monitoring and management of other health factors.

Homocysteine Test Booking & Reports – Metropolis Healthcare India

How to Book a Homocysteine Test?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select Homocysteine Test, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab.
  2. Safe Home Sample Collection
    Our trained phlebotomists ensure timely collection of your sample while strictly following all safety and hygiene protocols.
  3. Sample Tracking Updates
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
  4. Accurate Laboratory Testing
    Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results.
  5. Quick & Easy Reports
    Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.

Is home sample collection for Homocysteine Test available near you?

Yes, Metropolis Healthcare provides home sample collection for the Homocysteine Test. Our trained phlebotomists follow strict safety protocols while collecting your blood sample at your preferred location and time. This service ensures accurate results while providing you with the comfort and convenience of staying home.

How Long Does It Take to Get a Homocysteine Test Report?

Reports are usually available after 6 hours once the sample reaches the lab.

Note: Reporting time and cost may vary depending on your location.

Where can I see or get Homocysteine Test results?

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp and you also have the option to collect a physical copy directly from the lab.

Interpreting Homocysteine Test Results

What Your Homocysteine Test Results May Indicate

The table below shows the reference range and what different homocysteine levels might mean for your health:

Parameter

Reference Range

High Levels May Indicate

Low Levels May Indicate

Homocysteine

5-15 μmol/L

Vitamin deficiency (B12, B6, folate), cardiovascular risk, homocystinuria, kidney disease

Generally not clinically significant

 

Conditions that May Affect Homocysteine Test Accuracy

Several factors can influence your Homocysteine Test results and should be discussed with your doctor:

• Certain medications like methotrexate, carbamazepine, phenytoin, and anticonvulsants can increase homocysteine levels
• Vitamin B supplements may lower homocysteine levels and affect test interpretation
• Dehydration can concentrate blood substances, potentially leading to falsely elevated readings
• Recent alcohol consumption or cigarette smoking may influence results
• Kidney or liver disease can affect how your body processes homocysteine
• Post-menopausal state in women may naturally increase homocysteine levels

How is a Homocysteine Test Done?

The Homocysteine Test follows a standard blood collection procedure:

• A healthcare professional will tie a band around your upper arm to make veins more visible
• The injection site is cleaned with an antiseptic solution
• A small needle is inserted into a vein, usually in your arm
• Blood is collected into a special gel vacutainer tube (2ml required)
• The needle is removed and a bandage is applied to the site
• The entire procedure typically takes less than five minutes
• Your sample is then sent to the laboratory for analysis using advanced testing methods

How Should You Prepare for a Homocysteine Test?

Proper preparation ensures accurate test results and a smooth testing experience:

No fasting required - You can drink and eat normally before the blood sample collection for this test
Medication consultation - Inform your doctor about all medications and supplements you're taking
Stay hydrated - Drink adequate water before starting your fast to prevent dehydration
Avoid alcohol and smoking - These can affect homocysteine levels and should be avoided before testing
Wear comfortable clothing - Choose clothes with sleeves that can be easily rolled up for blood collection

Diseases that a Homocysteine Test Can Help Detect

Vitamin deficiencies - B12, B6, and folate deficiencies that affect protein metabolism
Homocystinuria - A rare genetic disorder affecting amino acid processing
Cardiovascular disease risk - Elevated levels associated with heart disease and stroke
Deep vein thrombosis - Blood clot formation risk assessment
Pregnancy complications - Maternal hyper-homocysteinaemia-related risks
Neurological disorders - Conditions affecting brain and nerve function
Chronic kidney disease - Kidney function-related metabolic changes

Homocysteine Test/Packages that You Can Book With Metropolis Healthcare

Metropolis Healthcare offers comprehensive testing options that complement the Homocysteine Test for complete health assessment:

Test/Package Name

Purpose/Highlights

Homocysteine Reflex B12-Folate

Comprehensive evaluation including vitamin B12 and folate levels

Cardiac Risk Profile Test

Complete cardiovascular risk assessment including multiple heart health markers

Cardiac Screen-1

Basic cardiac screening package for early detection of heart-related issues

 

Homocysteine Test Prices in Different Cities

The cost of a Homocysteine Test may vary depending on your location. Here's a table showing the approximate prices in different cities.

City

Approximate Price (INR)

Mumbai

₹1000 to ₹1500

Delhi

₹1000 to ₹1500

Bangalore

₹1000 to ₹1500

Hyderabad

₹1000 to ₹1500

Chennai

₹1000 to ₹1500


Reference:

  • Kit Insert
  • Maron BA, Loscalzo J. The treatment of hyperhomocysteinemia. Annu Rev Med. 2009;60:39-54
Read More

Homocysteine Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Homocysteine Test with a clear pricing structure.

The Homocysteine Test Price in Mumbai is ₹ 1,450 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

No fasting is required for the Homocysteine Test. You can eat and drink as usual, but always follow your doctor’s instructions based on your specific health needs or other tests.

Overnight fasting is not mandatory for the Homocysteine Test. You can eat and drink as usual. However, follow your doctor’s guidance for any specific instructions.

Yes, dehydration can concentrate blood components and potentially lead to falsely elevated homocysteine readings. Stay normally hydrated for accurate results.

You can follow your normal diet and take your regular medications before the Homocysteine Test. However, inform your doctor about all medications, as certain medicines like methotrexate, carbamazepine, phenytoin, and anticonvulsants can increase homocysteine levels.

A healthcare professional will tie a band around your upper arm, clean the area, and insert a small needle into a vein. Blood is collected into a vial, and the procedure typically takes less than five minutes.

The risks are minimal and similar to any standard blood test. You may experience slight pain or bruising at the needle site, feel lightheaded, or in rare cases, develop an infection.

Normal homocysteine levels are typically 5-15 μmol/L. Levels above 15 μmol/L are considered moderately elevated and may require medical attention and treatment.

The test is also known as Total Homocysteine or Plasma Total Homocysteine.

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