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Vitamin B12 Test

Also known as: Vitamin B12 (Cyanocobalamin) Test

70+ booked in last 3 days

Vitamin B12 (Cyanocobalamin) Test Details in Brief

Also Known As Vitamin B12 (Cyanocobalamin), Serum; Cyanocobalamin Test; B12 Vitamin Deficiency Test
Purpose Helps in diagnosing vitamin B12 deficiency, supports the evaluation of anaemia and neurological disorders, and is useful in assessing pernicious anaemia.
Preparation Clinical history is required; high biotin doses (> 5 mg/day) should be avoided at least 8 hours before blood collection.
Fasting Not Required
Reporting Time After 6 hours
Cost 1,250

What Is a Vitamin B12 Test?

A vitamin B12 test is a medical diagnostic procedure that measures the concentration of vitamin B12, or cyanocobalamin, in your blood. This essential vitamin plays a crucial role in nerve function, red blood cell formation, and DNA synthesis.

The test requires a blood sample, typically drawn from a vein in your arm. It helps detect vitamin B12 deficiency, which can cause various health problems, including anaemia and neurological issues.

What Does the Vitamin B12 Test Measure?

The vitamin B12 test provides valuable insights into your body's nutritional status and overall health:

Diagnoses vitamin B12 deficiency: Determines if your levels are below the normal range.
Identifies the cause of anaemia: Specifically helps diagnose megaloblastic anaemia, where your body produces abnormally large red blood cells.
Investigates neurological symptoms: Finds the cause of unexplained numbness, tingling, memory problems, or balance difficulties.
Monitors high-risk individuals: Screens people more susceptible to deficiency, such as older adults and vegetarians.
Evaluates treatment effectiveness: Checks if B12 supplements or injections are successfully restoring normal B12 levels.

Vitamin B12 Test: Who Needs It and Why It's Done

What Symptoms May Call for a Vitamin B12 Test?

Your doctor may recommend a vitamin B12 test if you experience persistent or concerning symptoms:

General Physical Symptoms:
• Constant weakness, tiredness, or lightheadedness
• Pale or yellowish skin
• A sore, smooth, and red tongue or mouth ulcers
• Shortness of breath and heart palpitations

Neurological Symptoms:
• Numbness, tingling, or "pins and needles" sensation, especially in hands and feet.
• Difficulty walking or balance problems
• Vision disturbances

Psychological and Cognitive Symptoms:
• Memory loss, confusion, or difficulty reasoning
• Changes in mood, including increased irritability or depression.

Who Should Get a Vitamin B12 Test?

Certain groups of people benefit from regular vitamin B12 testing:

People with symptoms: Anyone experiencing the symptoms of vitamin B12 deficiency, such as constant weakness, shortness of breath, numbness, changes in mood, etc.
Vegetarians and vegans: Since B12 is found mainly in animal products, those following plant-based diets face a higher risk.
Older adults: The ability to absorb B12 from food decreases with age, making individuals over 50 more susceptible.
Patients with digestive conditions: People with Crohn's disease, coeliac disease, or gastritis that interfere with nutrient absorption.
Individuals post-surgery: Those who have had gastrointestinal surgeries affecting nutrient absorption.
People on certain medications: Long-term use of medicines like metformin or acid-reducing medications.
Pregnant or breastfeeding women: Especially those following vegetarian diets, as deficiency can affect the baby's development.

Why Is a Vitamin B12 Test Done?

A vitamin B12 test is done to accurately diagnose a deficiency that, if left untreated, can lead to serious and sometimes irreversible health complications, including severe anaemia and permanent nerve damage.

Importance of a Vitamin B12 Test

The vitamin B12 test holds significant clinical importance because it provides a clear, early diagnosis of a deficiency that often presents with vague symptoms. Early detection allows prompt treatment before severe or permanent damage occurs, particularly to your nervous system.

The test results help your doctor determine the most appropriate treatment approach, whether through dietary changes, oral supplements, or vitamin B12 injections. It also helps doctors differentiate B12 deficiency from other conditions with similar symptoms, ensuring you receive the correct treatment for optimal recovery.

Vitamin B12 Test Booking & Reports – Metropolis Healthcare India

How to Book a Vitamin B12 Test?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the 'Vitamin B12 Test', choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab.
  2. Safe Home Sample Collection
    Our trained phlebotomists ensure the timely collection of your sample while strictly following all safety and hygiene protocols.
  3. Sample Tracking Updates
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
  4. Accurate Laboratory Testing
    Your sample is processed at our NABL- & CAP-accredited laboratories, where expert technicians ensure accurate results.
  5. Quick & Easy Reports
    Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.

Is Home Sample Collection for the Vitamin B12 Test Available Near You?

Yes, home sample collection is available for the vitamin B12 test at Metropolis Healthcare. Our trained phlebotomists visit your location at your preferred time, ensuring safe and comfortable sample collection. This service eliminates travel time and waiting queues, making your health check simple and stress-free while maintaining the same accuracy and reliability.

How Long Does It Take to Get a Vitamin B12 Test Report?

Reports are usually available within 6 hours once the sample reaches the lab.

Where Can I See or Get the Vitamin B12 Test Results?

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.

Interpreting Vitamin B12 Test Results

What Your Vitamin B12 Test Results May Indicate

The table below shows the reference range and what different vitamin B12 levels might mean for your health:

Parameter

Reference Range

High Values May Indicate

Low Values May Indicate

Vitamin B12 (Cyanocobalamin)

197-771 pg/mL

Excessive supplementation, liver disease, and certain blood disorders

Vitamin B12 deficiency, pernicious anaemia, malabsorption disorders, strict vegetarian diet

 

Conditions that May Affect Vitamin B12 Test Accuracy

Several factors can influence your vitamin B12 test results and should be discussed with your doctor:

High biotin supplementation: Biotin doses above 5 mg daily can interfere with test accuracy if taken within 8 hours before testing.
Certain medications: Long-term use of metformin, proton pump inhibitors, or H2 blockers can affect B12 absorption.
Dehydration: Can concentrate blood substances, potentially leading to falsely elevated readings.
Recent B12 supplementation: Taking vitamin B12 supplements shortly before testing may temporarily elevate levels.
Sample quality issues: Haemolysed, lipemic, or icteric samples can affect test accuracy.
Timing of collection: Blood drawn too soon after eating may show temporary fluctuations.

How Is a Vitamin B12 Test Done?

The vitamin B12 test involves a straightforward blood collection process:

• A healthcare professional will tie an elastic band around your upper arm to make the vein more visible.
• The area where the needle will be inserted is cleaned with an antiseptic.
• A small needle is inserted into the vein to collect a blood sample in a vial.
• The blood sample is collected in a gel vacutainer and requires 3 ml of serum.
• Your sample is sent to the laboratory, where it's analysed using electrochemiluminescence immunoassay (ECLIA).
• The entire procedure typically takes less than five minutes.

How Should You Prepare for a Vitamin B12 Test?

Preparing for your vitamin B12 test requires minimal steps:

Medication review: Inform your doctor about all medications and supplements you're taking.
Biotin supplementation: Avoid high biotin doses (>5 mg/day) for at least 8 hours before blood collection.
Clinical history: Be prepared to discuss your symptoms and medical history with your healthcare provider.

Diseases that a Vitamin B12 Test Can Help Detect

A vitamin B12 test can help identify several important health conditions:

Pernicious anaemia: An autoimmune condition affecting B12 absorption
Megaloblastic anaemia: Characterised by abnormally large, immature red blood cells
Vitamin B12 deficiency: Caused by inadequate dietary intake or absorption problems
Peripheral neuropathy: Nerve damage causing numbness and tingling
Malabsorption syndromes: Including Crohn's disease and coeliac disease
Neurological disorders: Related to B12 deficiency affecting brain and nerve function
Depression and cognitive impairment: Associated with low vitamin B12 levels

Vitamin B12 Tests/Packages that You Can Book With Metropolis Healthcare

Metropolis Healthcare offers comprehensive testing options to assess your vitamin B12 status and overall nutritional health:

Test/Package

Purpose/Highlights

Vitamin B Complex Profile

Comprehensive assessment of all B vitamins, including B1, B2, B6, B12, and folate levels

Vitamin B12, Active Holo Transcobalamin Serum

Measures the active form of vitamin B12 for more precise deficiency detection

Vitamin Profile Test

Complete evaluation of essential vitamins, including A, D, E, K, and B vitamins

 

Vitamin B12 Test Prices in Different Cities

The cost of a vitamin B12 test may vary depending on your location. Here's a table showing the approximate prices in different cities.

City

Price (₹)

Mumbai

₹600 to ₹1300

Delhi

₹600 to ₹1300

Bangalore

₹600 to ₹1300

Chennai

₹600 to ₹1300

Pune

₹600 to ₹1300

Ahmedabad

₹600 to ₹1300

Read More

Vitamin B12 (Cyanocobalamin) Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Vitamin B12 (Cyanocobalamin) Test with a clear pricing structure.

The Vitamin B12 (Cyanocobalamin) Test Price in Mumbai is ₹ 1,250 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Untreated vitamin B12 deficiency can lead to serious complications, including megaloblastic anaemia, permanent nerve damage, memory loss, confusion, and increased cardiovascular disease risk due to elevated homocysteine levels.

Yes, there is a strong connection. Vitamin B12 is essential for producing brain chemicals that affect mood. A deficiency can contribute to or worsen symptoms of depression and anxiety disorders.

This is a common misconception. Fruits do not naturally contain significant amounts of vitamin B12. B12 is produced by microorganisms and found almost exclusively in animal products and fortified foods.

For vegetarians, the best sources include dairy products like milk, curd, paneer, and cheese, plus fortified foods such as breakfast cereals, nutritional yeast, and fortified plant-based milk alternatives.

Excellent non-vegetarian sources include fatty fish like tuna and salmon, shellfish, organ meats like liver, red meat, eggs, and poultry, which provide readily absorbable vitamin B12.

The most reliable approach is regularly consuming B12-fortified foods or taking vitamin B12 supplements. Consulting a doctor or registered dietitian helps determine the right dosage and frequency.

Certain medications can interfere with B12 absorption, including metformin for diabetes, proton pump inhibitors for acid reflux, H2 blockers, and some antibiotics and anticonvulsants when used long-term.

General symptoms like fatigue may improve within weeks. However, neurological symptoms may take several months to improve, and severe, long-standing deficiency may cause some permanent nerve damage.

The test can be taken at any time, but laboratories often prefer morning samples for consistency with reference ranges because fasting may be recommended in some cases.

No, overnight fasting is not required for a vit B12 test. However, consult your doctor and follow their instructions, as individual cases may vary based on medical history.

Yes, dehydration reduces blood fluid volume, making it more concentrated. This can falsely increase measured vitamin B12 levels, potentially masking a deficiency. Stay well-hydrated before your test.

You can eat and drink normally before a vitamin B12 test. Inform your doctor about all medications and supplements, especially biotin, which can interfere with results if taken recently.

A healthcare professional ties a tourniquet around your upper arm, cleans the area with an antiseptic, and then inserts a small needle into the vein to collect blood. The quick procedure takes less than five minutes.

Based on the reference range, normal B12 levels are 197-771 pg/mL. Values below this range may indicate deficiency, while levels above may suggest excessive supplementation or other conditions.

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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