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Immunofixation Quantitative Serum Test

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Immunofixation Quantitative Test Overview

Immunofixation (IF) is a laboratory technique used to detect and identify specific proteins in a blood or urine sample. It is typically used to diagnose and monitor certain diseases, such as multiple myeloma and other disorders involving abnormal protein production. Immunofixation-Quantitative Serum is a variation of this technique that provides additional information about the amount of specific proteins in the sample. In this test, the sample is first separated into its individual components using a process called electrophoresis. Then, antibodies that are specific to the target proteins are added to the separated components. These antibodies bind to the proteins, which are then visualized using a detection method, such as a stain or fluorescent dye.

Written By: Supriya Kulkarni, Lead-Content & Training

Reviewed By: Dr. Alap Christry M.D. AVP-Lab Operations & Scientific Business Head-Clinical Chemistry

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Immunofixation Quantitative Serum Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Immunofixation Quantitative Serum Test with a clear pricing structure.

The Immunofixation Quantitative Serum Test Price in Mumbai is ₹ 7,870 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The Immunofixation Quantitative Serum (IFQS) test is a laboratory test that measures the levels of specific proteins in the blood. Specifically, it measures the amount of immunoglobulins (antibodies) in the blood, including immunoglobulins (IgG, IgM, IgA, IgD, and IgE), which are proteins produced by the immune system to help fight infections and other foreign substances in the body.

Immunofixation quantitative serum test is done for various reasons, such as:

  1. To diagnose multiple myeloma: The test helps in detecting abnormal proteins in the blood, which are often seen in multiple myeloma, a type of cancer that affects plasma cells.
  2. To monitor treatment progress: The test is useful in monitoring the response to treatment for multiple myeloma and other conditions that involve abnormal protein production.
  3. To identify monoclonal gammopathy of undetermined significance (MGUS): MGUS is a condition where the body produces abnormal proteins but does not cause any symptoms. The test helps in detecting this condition and monitoring it for any progression.
  4. To evaluate kidney function: The test is sometimes done as part of a kidney function evaluation to check for any damage to the kidneys due to the presence of abnormal proteins.
  5. To detect other conditions: The test can also help in detecting other conditions that involve abnormal protein production, such as Waldenstrom macroglobulinemia and amyloidosis.
  6. To differentiate between types of abnormal proteins: The test can help in identifying the specific type of abnormal protein present in the blood, which can provide important information for diagnosis and treatment.
  7. To monitor disease recurrence: The test can be useful in monitoring for disease recurrence in patients who have previously been treated for multiple myeloma or other conditions that involve abnormal protein production.

Some symptoms that may call for an Immunofixation Quantitative Serum test include:

  • Unexplained fatigue
  • Bone pain
  • Frequent infections
  • Weakness
  • Loss of appetite
  • Unexplained weight loss
  • Anemia
  • Elevated calcium levels in the blood
  • Protein in the urine

Abnormal results on this test can indicate a range of conditions, including autoimmune disorders, infections, and cancer.

The test involves drawing a small amount of blood from a vein in your arm. A healthcare professional will clean the area with an antiseptic, wrap an elastic band around your upper arm to make the veins more visible, and insert a needle into a vein to collect the blood sample. You may feel a brief prick or stinging sensation when the needle is inserted, but the procedure is generally painless.

No special preparation is required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.

In addition to the Immunofixation Quantitative Serum test, other laboratory tests that may be ordered to complement the evaluation of immune system function include:

  1. Complete Blood Count (CBC): A blood test that provides information about the number and types of blood cells, including white blood cells, red blood cells, and platelets.
  2. Serum Protein Electrophoresis (SPEP): It is often ordered to provide a more comprehensive evaluation of immunoglobulin levels.
  3. Urine Protein Electrophoresis (UPEP): It is commonly used to diagnose and monitor multiple myeloma.
  4. Rheumatoid Factor (RF): A blood test that measures the levels of antibodies that target the body's own tissues, which can be elevated in autoimmune diseases such as rheumatoid arthritis.
  5. Antinuclear Antibody (ANA): A blood test that detects the presence of antibodies that target the cell nucleus, which can be elevated in autoimmune diseases such as lupus.
  6. Complement Levels: A blood test that measures the levels of proteins in the blood that help to activate and regulate the immune system.
  7. C-reactive Protein (CRP): A blood test that measures the levels of a protein that is produced in response to inflammation in the body.
  1. Serum Protein Electrophoresis (SPEP) with Immunofixation
  2. Immunoelectrophoresis (IEP) with Quantitation
  3. Immunofixation Electrophoresis (IFE) with Quantitation
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