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Vanillyl Mandelic Acid (VMA), 24 Hours Urine
Also known as: VMA (Vanillyl Mandelic Acid) - Quantitative, Urine 24 Hrs
No special precautions
Sample Type
Urine
Recommended for
Male
Recommended for
Male, Female
Report
Within 1 Week
Blood test at Home
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Accurate & Quality Test Reports
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Overview
Catecholamines include dopamine (found mostly in the central nervous system), norepinephrine (mainly in the sympathetic nervous system) and epinephrine (mainly in the adrenal medulla). They are stored as an inactive complex. Released catecholamines, having a short half-life, are taken up by sympathetic nerve endings, or metabolized by the liver and kidney and excreted. Vanillylmandelic acid (VMA) and 4-hydroxy-3-methoxy-mandelic acid (HMMA) are the end product of both epinephrine and norepinephrine catabolism. Quantitation of acidic metabolites has long proven to be a reliable diagnostic as well as a commonly used follow-up procedure for pheochromocytoma and other catecholamine-producing tumors. The prevalence of pheochromocytoma is 0.1% to 0.2% in hypertensive patients. Pheochromocytomas have a long record of misdiagnosis due to the metabolic, cardiac and gastrointestinal symptoms that can mimic many other diseases. These if undetected or mistreated can be fatal. However, since this is a surgically curable disease early diagnosis by demonstration of excess VMA excretion is critically important.
VMA (Vanillyl Mandelic Acid) - Quantitative, Urine 24 Hrs Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the VMA (Vanillyl Mandelic Acid) - Quantitative, Urine 24 Hrs with a clear pricing structure.
The VMA (Vanillyl Mandelic Acid) - Quantitative, Urine 24 Hrs Price in Mumbai is ₹ 3,795 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
This test measures the levels of the Vanillyl Mandelic Acid (VMA) in a 24-hour urine sample. VMA is a breakdown product of epinephrine and norepinephrine, which are hormones involved in the body's stress response.
- To diagnose pheochromocytoma, a tumour that produces excess catecholamines.
- To monitor the effectiveness of treatment for pheochromocytoma.
- To detect other catecholamine-producing tumours or abnormalities.
- To evaluate symptoms like high blood pressure, headaches, or excessive sweating that may be caused by excess catecholamines.
- Patients with symptoms like high blood pressure, unexplained headaches, or excessive sweating
- Individuals with a family history of pheochromocytoma or genetic risk factors.
- Those who have been previously diagnosed with pheochromocytoma or other catecholamine-producing tumours
- Patients being evaluated for other conditions affecting catecholamine levels
The normal range varies depending on age and sex and is typically <8-12 mg/24 hours. Elevated levels may indicate pheochromocytoma or other conditions affecting catecholamine levels. Abnormal results do not confirm a diagnosis and need to be interpreted by a doctor considering the patient's medical history, symptoms, and other diagnostic tests.
- You will be provided with a container to collect all your urine over 24 hours.
- Store the sample in a refrigerator until you submit it to the lab.
- Avoid certain foods and medications as advised by your doctor.
- Your urine sample will be analysed using liquid chromatography-tandem mass spectrometry (LC MSMS).
- The test is painless but collecting a 24-hour urine sample may require some planning.
What preparations are required before the Vanillyl Mandelic Acid (VMA) test?
- Catecholamines Blood Test: Measures the levels of epinephrine, norepinephrine, and dopamine in the blood
- Computed Tomography (CT) Scan or Ultrasound: Imaging tests to locate tumours or abnormalities in the adrenal glands or other areas
- Medication history and other relevant tests as determined by your doctor
- VMA Test
- Vanillylmandelic Acid Test
Pheochromocytoma is a rare tumour that develops in the adrenal glands, which are located on top of the kidneys. It produces excess catecholamines, causing symptoms like high blood pressure, headaches, sweating, and anxiety. Early diagnosis is essential for effective treatment.
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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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