Paul-Bunnel Test by Agglutination - Serum

This test detects infectious mononucleosis (IM) heterophile antibodies in serum.

• To diagnose infectious mononucleosis • To confirm a suspected diagnosis of Epstein-Barr virus infection • To rule out other conditions that can cause similar symptoms • To monitor the effectiveness of treatment • To assess potential complications and risk of transmission

This test may be recommended if you have • symptoms suggestive of infectious mononucleosis, including fatigue, fever, sore throat, swollen lymph nodes, and enlarged spleen, • a suspected Epstein-Barr virus infection, • a family history or genetic risk factors for Epstein-Barr virus infection, or • symptoms suggestive of other conditions that can cause similar symptoms.

Elevated levels may indicate an acute or previous Epstein-Barr virus infection.

A healthcare provider will insert a needle into your vein to collect a sample of blood. They will send this sample to a laboratory for testing.

• You do not need to fast or make any special preparations before the test. • Discuss with your doctor any medications or supplements you're taking that could interfere with the test. • Inform your doctor if you have any specific requirements.

• Complete blood count (CBC) to check for abnormalities in blood cell counts • Liver function tests to assess liver health • Monospot test to detect heterophile antibodies in blood within a few days of symptom onset

Monospot test or Heterophile antibody test

Infectious mononucleosis, also known as mono or the kissing disease, is a common viral infection caused by the Epstein-Barr virus. It typically affects teenagers and young adults and is spread through contact with infected saliva. Symptoms include fatigue, fever, sore throat, swollen lymph nodes, and enlarged spleen.