Panfungal-DNA Detection by PCR & Sanger Sequencing – Tissue

This test detects the presence of fungal DNA in tissue samples.

This test is mainly done to diagnose fungal infections. It is particularly useful in cases where other diagnostic methods, such as culture-based tests, may not provide accurate results or take longer to yield a diagnosis. The test also helps in guiding appropriate antifungal therapy and monitoring treatment effectiveness.

This test may be recommended if you have • Suspected fungal infection in your tissues. • Symptoms suggestive of a fungal infection such as persistent fever, cough, skin rash, or sinusitis. • A compromised immune system, such as due to HIV/AIDS or organ transplantation. • Fungal infection that has not responded to initial treatment. • Underlying conditions that increase the risk of developing fungal infections, such as diabetes or certain types of cancer.

The test results will be compared to a normal range to determine if fungal DNA is present in the tissue sample. Abnormal results may indicate the presence of a fungal infection and may warrant additional tests, such as fungal culture or histopathological examination, to further characterise the specific fungi causing the infection.

During this test, a small piece of tissue will be collected from the affected area using a sterile technique. The tissue sample will be processed in the laboratory.

Before this test: • It is essential to provide accurate clinical history, including information about symptoms, duration, and previous treatments. • Your healthcare provider may advise you to stop certain medications that can interfere with the test results. • Follow any specific instructions provided by your doctor regarding fasting or medication restrictions before the test. Please reach out to your healthcare provider for any specific requirements.

In addition to the Panfungal-DNA Detection by PCR & Sanger Sequencing – Tissue, your healthcare provider may consider ordering other tests such as: • Fungal culture: This test helps grow and identify specific fungi present in a sample. • Histopathological examination: Microscopic examination of tissue samples to identify fungal elements and patterns of tissue damage caused by the infection.

Fungal DNA Detection by PCR & Sanger Sequencing in Tissue

A fungal infection is caused by various types of fungi and can affect different parts of the body, including the skin, nails, lungs, and internal organs. Fungal infections may range from mild localized conditions to severe systemic infections. Prompt and accurate diagnosis is crucial for appropriate treatment and prevention of complications.