Panfungal-DNA Detection by PCR & Sanger Sequencing – CSF
Also known as: Panfungal DNA Detection, CSF
Overview
The "Panfungal-DNA detection by PCR & Sanger Sequencing - CSF" is a molecular diagnostic test used to detect the presence of fungal DNA in cerebrospinal fluid (CSF) samples. This test is employed to diagnose fungal infections that involve the central nervous system, such as fungal meningitis or encephalitis. The clinical utility of this test lies in its ability to provide a more sensitive and specific approach to identify a wide range of fungal pathogens in CSF samples. Traditional culture methods may have limitations in detecting certain fungal species, but PCR amplification and Sanger sequencing offer a more accurate and comprehensive method for species identification. Timely and accurate identification of the causative fungal species is crucial for guiding appropriate antifungal therapy, especially in cases where fungal infections can be difficult to diagnose and treat. This test is an essential tool for healthcare providers in diagnosing fungal infections of the central nervous system, allowing for more targeted and effective management of patients with fungal CNS diseases.
Panfungal DNA Detection, CSF Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Panfungal DNA Detection, CSF with a clear pricing structure.
The Panfungal DNA Detection, CSF Price in Mumbai is ₹ 9,540 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
This test detects the presence of fungal DNA in cerebrospinal fluid.
This test is primarily done to diagnose fungal infections in the central nervous system. It also helps monitor the effectiveness of antifungal treatment. Other reasons to perform this test include identifying fungal species, guiding treatment decisions, and assessing the risk of developing fungal-related complications.
• This test is recommended for individuals with symptoms or risk factors suggestive of a fungal infection in the central nervous system (e.g., persistent headaches, altered mental status). • Patients with immunocompromised conditions, such as HIV/AIDS or organ transplant recipients, may require this test to rule out fungal infections. • Additionally, patients with suspected meningitis or encephalitis may also undergo this test.
Abnormal results, i.e., a result indicating the presence of fungal DNA in CSF, suggest the presence of a fungal infection in the central nervous system.
During this test, a sample of cerebrospinal fluid (CSF) will be collected using a sterile, leak-proof container during a lumbar puncture procedure. The CSF sample will then be sent to the laboratory for analysis.
To prepare for this test: • A lumbar puncture procedure will be performed to collect cerebrospinal fluid. • Follow any fasting instructions given by your doctor. • Inform your doctor about any medications you are taking, including antibiotics or antifungal drugs. • Provide any relevant medical history or clinical details as requested by your doctor. Please reach out to your healthcare provider for any specific requirements.
Other tests that may be ordered alongside the Panfungal-DNA Detection by PCR & Sanger Sequencing – CSF include: • Fungal culture: This test helps grow and identify the specific fungal species causing the infection. • Blood tests: To assess the overall health, immune status, and presence of any systemic fungal infections. • Imaging studies, such as MRI or CT scan: To evaluate the extent and location of the infection within the central nervous system.
PCR and Sanger sequencing for fungal DNA in cerebrospinal fluid
A fungal infection in the central nervous system refers to an infection caused by fungi that invade the brain, spinal cord, or meninges. These infections can be serious and may lead to meningitis, encephalitis, or other neurological complications.
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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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