Nitrosonaphthol Test - Qualitative, Spot Urine

This test measures the concentration of tyrosine in your urine.

• To detect high concentrations of tyrosine in the urine
• To diagnose and monitor conditions related to abnormal tyrosine metabolism

This test may be recommended if you have symptoms or risk factors associated with metabolic disorders or liver diseases such as

• jaundice,
• liver dysfunction,
• family history of metabolic disorders, and
• suspected amino acid metabolism disorders.

Abnormal results may suggest the presence of metabolic disorders or liver diseases, but further evaluation is needed for a definitive diagnosis.

You will need to provide a spot urine sample in a leakproof container.

The sample will be sent to the laboratory for analysis.

• Avoid consuming bananas, tea, coffee, and cold drinks before the test.
• Inform your doctor about any medications or supplements you are taking. Also, tell them if you have any specific requirements.
• Follow any additional instructions given by your doctor regarding fasting or dietary restrictions before the test.

• Liver function tests: These blood tests assess the overall health and function of your liver.
• Amino acid profile: This test measures the levels of various amino acids in your blood, providing information about their metabolism.
• Genetic testing: This may be recommended to identify specific gene mutations related to metabolic disorders.

Spot urine tyrosine test or Urine tyrosine concentration test

Tyrosinemia is a rare genetic disorder characterised by the inability to break down the amino acid tyrosine. This can lead to the accumulation of toxic substances and cause various health problems. Hereditary tyrosinemia type I is the most severe form and can lead to liver and kidney dysfunction if left untreated. Tyrosinemia type II and type III are relatively milder conditions with fewer systemic complications.