Tacrolimus-by LCMS Test in Indore
Tacrolimus (Prograf) is a macrolide antibiotic derived from the fungus Streptomyces tsukubaenesis.
Tacrolimus is a immunosuppressant and requires therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations.
This test is done for calculation of amount of drug tacrolimus in your blood.
Tacrolimus (Prograf) is a macrolide antibiotic derived from the fungus Streptomyces tsukubaenesis. Tacrolimus is metabolized by CYP3A4; thus, its concentration is affected by drugs that inhibit (calcium channel blockers, antifungal agents, some antibiotics, grapefruit juice) or induce (anticonvulsants, rifampin) this enzyme. Tacrolimus has a narrow therapeutic range and adverse effects are common, particularly at high dose and concentrations, making therapeutic drug monitoring essential.
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Yes our laboratory is accredited by the NABL (National Accreditation Board of Testing and Calibration of Laboratories) India & College of American Pathologists (CAP). This accreditation process is carried out every 2 years for NABL & annually for CAP with periodic internal audits carried out twice in a year. All our aforementioned tests are accredited by NABL & CAP.
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