CD43 IHC

The CD43 IHC test measures the presence of CD43 protein on the surface of cells. When T cells become cancerous, they often continue to express CD43 protein.

• Diagnose T-cell lymphomas, such as T-cell acute lymphoblastic leukemia (T-ALL) and T-cell non-Hodgkin lymphoma (T-NHL)
• Diagnose myeloid leukemias, such as acute myeloid leukemia (AML)
• Determine the stage of certain types of cancer
• Monitor the progress of treatment for certain types of cancer
• Detect recurrence of certain types of cancer

Doctors recommend the CD43 test under the following circumstances:

• Symptoms of T-cell lymphoma or myeloid leukemia, such as fever, fatigue, and weight loss
• A family history of T-cell lymphoma or myeloid leukemia

Abnormal results may indicate that T-cell lymphoma or myeloid leukemia is present. However, abnormal results do not necessarily mean that you have a serious condition. It is important to consult your doctor for a proper evaluation and further guidance.

• The CD43 IHC test is performed on a tissue sample that is obtained from a biopsy or surgery.
• A biopsy is a procedure in which a small sample of tissue is removed from the body. Surgery is a procedure in which a larger piece of tissue is removed.
• The tissue sample is then sent to a laboratory, where it is stained with antibodies that bind to CD43 protein.
• The stained tissue sample is then examined under a microscope to see if there is any CD43 protein present.

Before the CD43 test:

• Ensure you have the necessary tissue sample or biopsy report available for testing.
• Provide any relevant clinical information, including symptoms, medical history, and radiological reports.
• Follow specific instructions from your doctor regarding fasting or medication discontinuation, if required.

• Flow cytometry: A technique used to analyse the physical and chemical characteristics of cells.
• Immunohistochemistry (IHC): A lab technique that uses antibodies to detect specific proteins in tissue samples.
• Bone marrow biopsy: A procedure to collect and examine a sample of bone marrow to diagnose blood disorders.

• IHC single marker with reporting CD43
• Immunohistochemistry for CD43
• CD43 immunostaining
• CD43 antibody staining
• CD43 marker test
• CD43 immunohistochemistry

T-cell lymphoma is a type of cancer that affects T cells, a critical component of the immune system. It typically presents as abnormal growths or tumours in the lymph nodes, skin, or other organs. T-cell lymphomas are classified as non-Hodgkin lymphomas (NHLs), a diverse group of cancers that originate from lymphocytes. While NHLs are less common than Hodgkin lymphoma, they account for the majority of lymphomas diagnosed each year.