Growth Hormone Suppression Test (Glucose)

This test measures the levels of growth hormone in your body after consuming a glucose solution. It helps evaluate the functioning of the pituitary gland, assess growth disorders, diagnose acromegaly, and monitor the effectiveness of treatment for growth hormone-related conditions.

This test is done for several reasons, including:

• To diagnose and monitor growth hormone-related conditions such as acromegaly or gigantism
• To assess abnormal growth patterns in children
• To evaluate the effectiveness of treatment for growth hormone-related disorders
• To identify causes of adult growth hormone deficiency or excess

This test may be recommended if you:

• Have symptoms suggestive of acromegaly or gigantism, such as enlarged hands or feet, facial changes, or joint pain
• Are a child or adolescent with abnormal growth patterns
• Have been diagnosed with a growth hormone-related disorder and need treatment monitoring
• Show signs of adult growth hormone deficiency or excess

The normal range for growth hormone levels after glucose consumption varies depending on the specific intervals measured. Abnormal results may indicate conditions such as acromegaly, gigantism, or growth hormone deficiency. However, abnormal results should be further evaluated by your doctor, who will consider your medical history, symptoms, and other diagnostic tests.

• You will be asked to provide several blood samples at different time intervals after consuming a glucose solution.
• The samples will be used to measure your growth hormone levels.
• The test is usually conducted in a clinical lab and takes a few hours to complete.

• You may need to fast for a specific period before the test.
• Your doctor may ask you to stop certain medications that can affect growth hormone levels.
• It's important to follow any additional instructions provided by your healthcare provider regarding diet, activity, and other lifestyle factors.

• Insulin-like Growth Factor 1 (IGF-1) Test: This test measures the levels of IGF-1, which is influenced by growth hormone. It also helps diagnose growth hormone disorders and monitor treatment response.
• Pituitary MRI: This evaluates the structure and function of the pituitary gland, which produces growth hormone.

Glucose Suppression Test or Oral Glucose Tolerance Test (OGTT) for Growth Hormone

Acromegaly is a rare hormonal disorder caused by excessive production of growth hormone in adulthood. It leads to abnormal growth of bones and tissues, resulting in enlarged features, joint problems, organ enlargement, and other health issues.