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Coeliac disease profile-1 Test

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Celiac disease (CD) is an immune-mediated enteropathy induced by dietary gluten causing inflammation of the small intestines that may lead to various gastrointestinal symptoms.

When a genetically predisposed individual consumes food containing gluten like wheat, barley, rye, and other grains, inflammation and damage of the small bowel mucosa occurs which leads to malabsorption, loss of bone density, miscarriage, infertility or even neurological diseases or certain cancers.

WRITTEN BY: Dr.Shibani R Medical Writer, Medical Affairs


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Coeliac disease profile-1 Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Coeliac disease profile-1 Test with a clear pricing structure.

The Coeliac disease profile-1 Test Price in Mumbai is ₹ 2,755 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The Celiac disease profile measures the endomysial Antibody, tTg antibody levels in the blood.

  • For diagnosing Coeliac disease, an autoimmune disorder of the small intestine.

People with the following symptoms:

  • Recurrent symptoms of diarrhoea with or without blood, constipation, nausea, vomiting, bloating on consumption of gluten or gluten induced food items.
  • Symptoms of gluten induced malabsorption, loss of bone density, infertility, neurological symptoms or even cancers.

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

Endomysial Antibody IgA

Presence of antibodies (Positive result) may be seen in gluten sensitive enteropathy (children: celiac disease, adult: non tropical sprue). Antibodies against endomysium and gliadin are rarely seen in healthy individuals and in other intestinal diseases.

tTG (Tissue Transglutaminase) IgA

tTG activity is increased (Positive Result) in the jejunal mucosa in Celiac disease/Gluten sensitive enteropathy, which is a chronic condition affecting genetically susceptible individuals.

Results should be correlated with the clinical features and with the other test results as well.

  • Endomysial Antibody test
  • tTG (Tissue Transglutaminase) Test
  • IgA test.

Antibodies against endomysium of class IgA can be found in gluten sensitive enteropathy [in children and adults].

tTG is a calcium-dependent enzyme widely distributed in body fluids and tissues especially the gastrointestinal submucosa. The test is used for the detection of autoantibodies of IgA class directed against tissue transglutaminase (tTG) in human serum or plasma.

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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