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Cytomegalovirus CMV IGM Antibody By CLIA Serum Test
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Blood
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CMV IgM Test Overview
Cytomegalovirus (CMV) infections are common but usually mild or asymptomatic. In pregnant women (if acquired first time during pregnancy), newborns & immunocompromised individuals i.e., transplant patients, HIV positives, immunosuppressive therapy etc. infection can have devastating consequences.
CMV IgM antibodies indicate a recent infection which may be primary, reactivation or reinfection. In exceptional cases despite infection IgM antibody levels may be low or undetectable i.e., infectious mononucleosis, immunocompromised individuals, pregnant women & transplant recipients.
Due to virus reactivation or a newly acquired infection, CMV is a substantial source of mortality and morbidity. It is found in people who have had a solid organ or bone marrow transplant, AIDS patients, and patients exposed to other immunosuppressants. Nearly any organ can become infected in these patient categories, resulting in multiorgan failure. CMV is considered one of the TORCH -- toxoplasmosis, other infections, rubella, cytomegalovirus, and herpes simplex virus categories of infections. It is one of the causes of congenital illness in infants:
- Toxoplasmosis.
- Syphilis.
- Rubella.
- CMV.
- Herpes simplex virus.
The herpesvirus family member, CMV, typically causes asymptomatic infection. It then resides latently in individuals, primarily in bone marrow-derived cells.
Infections with CMV are frequent. But they are typically slight or asymptomatic. Various CMV infections can have disastrous effects on the following categories of people:
- Pregnant women (if first acquired during pregnancy).
- Newborns.
- Immunocompromised people such as transplant recipients, HIV positives, etc.
- People on immunosuppressive therapy.
A recent infection, which could be initial, or reactivation, is indicated by CMV IgM antibodies. IgM antibody levels may occasionally be low or undetectable despite illness. This is particularly in the cases of infectious mononucleosis, those with impaired immune systems, expectant mothers, and transplant recipients.
This test is useful to:
- Aid in the detection of current or previous CMV infections.
- Determine previous CMV exposure.
This test, however, should not be used for selecting blood or plasma donors.
Written by: Dr Vishal Wadhwa, M.D, D.N.B Microbiology, Medical Affairs
Cytomegalovirus CMV IGM Antibody By CLIA Serum Test Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Cytomegalovirus CMV IGM Antibody By CLIA Serum Test with a clear pricing structure.
The Cytomegalovirus CMV IGM Antibody By CLIA Serum Test Price in Mumbai is ₹ 840 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
CMV igm test is done to aid the diagnosis of acute CMV infection. However, a small percentage of patients may not develop this antibody even post-infection. This is not a recommended test for patients with solid organ transplant (post-transplantation) & with other immunocompromised states
CMV igm test measures presence of IgM antibodies against CMV
CMV IgM test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in a vacutainer.
The presence of CMV IgM antibodies may indicate acute infection/ reactivation and can be deleterious to the health of immunocompromised patients.
However, a negative result does not rule out acute infection and thus a PCR to detect CMV nucleic acid is recommended especially in immunocompromised patients.
In pregnant women, it is important to know whether it is a primary acute infection or not and hence a positive CMV IgM case should be tested for avid IgG antibodies. The absence of avid IgG antibodies indicates a primary acute infection
The doctor prescribes the test to people who have a compromised immune system, are pregnant, or exhibit any of the following symptoms:
- Weakness or drowsiness.
- Discomfort in the throat.
- Swelling in your lymph nodes.
- Flu.
- Headache.
Muscular discomfort
The doctor can prescribe a CMV test to find out if the patient now has or has ever had a CMV infection.
Blood is used to perform the CMV serology test. A nursing assistant or lab technician often collects this sample in a clinical environment. They take blood from a vein on the arm or wrist using a tiny needle. The blood sample is then sent to a lab for evaluation. When the results are ready, the physician discusses them.
For this test, there is no need for preparation.
This test is used to diagnose acute CMV infection. Even after infection, a tiny proportion of people could not develop this antibody. Patients having solid organ transplants (post-transplantation) and those with various immunocompromised states should not undergo this test.
Patients with a weakened immune system and those who are expecting a child may be prescribed the test by a doctor. The doctor may also suggest this test if the person is experiencing the following symptoms:
- Fatigue or weakness.
- Throat discomfort.
- Enlargement of your lymph nodes.
- Flu.
- Headache.
- Pain in the muscles.
In order to identify particular infections in pregnant women and reduce the risk of birth abnormalities, the CMV test is frequently carried out as part of the TORCH testing panel. These tests often involve the diagnosis of Herpes simplex, Cytomegalovirus, Rubella, and Toxoplasmosis
CMV IgM assay
Cytomegalovirus IgM Test
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