CD16/56

This test measures the presence and levels of CD16 and CD56 proteins on natural killer cells. Normal levels of these cell proteins may be indicative of a proper functioning of the natural killer cells. High values of natural killer cells in the body may be suggestive of an underlying health issue.

This test is done primarily:

• To assess natural killer cell activity
• To evaluate immune function
• To monitor treatment effectiveness for immune-related disorders or cancers
• To diagnose conditions related to abnormal immune responses

Healthcare providers may recommend this test for:

• Patients with suspected immune system disorders
• Individuals with recurring infections
• Those with a history of cancer
• People undergoing treatment affecting the immune system

• Abnormal results may suggest immune system dysfunction or certain cancers.
• Further evaluation needed to identify underlying conditions.

Discuss results with your doctor for interpretation and follow-up care.

This test requires a blood sample.

During the test:

• A sample is collected using a needle inserted into a vein.
• The process is quick and relatively painless.
• Minimal discomfort might be experienced during blood draw.

There are no specific preparations required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.

Other tests that your doctor may recommend include:

• Natural Killer Cell Activity Assay: Measures NK cell function.
• Immunoglobulin Levels: Measures the number of antibodies, or immunoglobulins, in blood.
• Tumor Marker Tests: Detect specific cancer markers in blood.
• Genetic Testing: Identifies genetic factors impacting immune response.

• Natural Killer Cell Assay 
• NK Cell Marker Test

Natural killer cells are derived from Large Granular Lymphocytes (LGLs) which arise from a common NK/T progenitor cells. Natural killer cell activity refers to the ability of these cells to identify and destroy abnormal cells like virus-infected or cancerous cells without prior exposure to them. Impaired NK cell activity can lead to increased susceptibility to infections and certain cancers.