C4 (Complement-4)

C4 Complement-4 (Serum) measures the level of C4 protein in your blood. C4 is a component of your immune system that helps to prevent infections and plays a role in autoimmune disorders. By measuring the C4 level, doctors can assess the activity of these conditions and monitor treatment effectiveness.

This test has several uses, including:

• Monitoring autoimmune disorders like systemic lupus erythematosus (SLE).
• Assessing kidney diseases such as glomerulonephritis.
• Diagnosing immune complex diseases.
• Evaluating the response to treatment for autoimmune disorders and kidney diseases.

This test may be recommended if you have:

• An autoimmune disorder
• Symptoms such as joint pain, skin rashes, or kidney problems.
• A family history of autoimmune disorders.
• A known diagnosis of glomerulonephritis or other kidney diseases.

This test helps doctors monitor disease activity, assess treatment effectiveness, and guide further management.

The normal range for C4 levels in the blood varies, but diminished levels are often observed in autoimmune disorders like SLE, glomerulonephritis, and immune complex diseases. Abnormal results do not necessarily mean you have a serious condition, so it's important to discuss them with your doctor for proper interpretation and follow-up.

During the C4 (Serum) test:

• A healthcare professional will draw a small sample of your blood.
• The blood sample will be sent to a laboratory for analysis.
• The test uses a method called nephelometry to measure the C4 protein level in your blood.
• The whole process is quick and relatively painless.

To prepare for the test, remember the following:

• No special preparations are usually required.
• You can eat and drink normally before the test.
• Inform your doctor about any medications or supplements you're taking as they may affect the test results.
• Follow any specific instructions from your doctor/healthcare provider.

Other tests that may be ordered alongside the C4 (Serum) test include:

• Complement-3 (C3) (Serum): Measures another component of the immune system often affected by autoimmune disorders
• ANA Antinuclear Antibodies: Detects antibodies that target the nucleus of cells, commonly found in autoimmune diseases
• Kidney function tests: Help assess kidney health and diagnose conditions like glomerulonephritis

C4 serum test

Systemic Lupus Erythematosus (SLE) is an autoimmune disease where the body's immune system mistakenly attacks its own tissues and organs. It can affect various body systems, including joints, skin, kidneys, and blood cells. the C4 (Serum) test helps monitor disease activity in SLE.