Home Visit
Upload
Amphiphysin Antibody Neuronal Ag in Paraneoplastic Syndrome Serum
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
Anti-Amphiphysin Antibody Test Overview
The anti-amphiphysin antibody test is a specialised diagnostic tool used to detect the presence of autoantibodies directed against the amphiphysin protein in the blood. These antibodies are associated with various paraneoplastic neurological syndromes (PNS) and certain types of cancers, particularly small-cell lung cancer and breast cancer. The amphiphysin protein is found in synaptic vesicles and plays a crucial role in neurotransmitter release.
The anti-amphiphysin antibody test is an important tool for identifying individuals who may be experiencing neurological symptoms due to an underlying tumour or autoimmune condition. It helps healthcare providers diagnose and manage paraneoplastic neurological syndromes, monitor tumour recurrence, and guide appropriate treatment strategies. By detecting the presence of anti-amphiphysin antibodies, this test contributes to the early identification and management of potentially serious conditions.
Amphiphysin is a protein found in nerve cells, and these antibodies are produced when your immune system mistakenly attacks the nerve cells in your body. Amphiphysin plays a crucial role in cellular processes and is also associated with certain neurological disorders.
Reasons for Undergoing the Anti-Amphiphysin Antibody Test
The anti-amphiphysin antibody test is typically recommended for individuals presenting with symptoms suggestive of paraneoplastic neurological syndromes or when an underlying tumour is suspected. Reasons for undergoing this test include:
- Stiff-person syndrome: A rare neurological disorder characterised by progressive muscle stiffness and painful spasms.
- Paraneoplastic encephalomyelitis (PEM): An inflammatory condition affecting the brain and spinal cord, often associated with underlying cancer.
- Sensory neuronopathy (SN): A disorder affecting the sensory neurones, leading to numbness, tingling, and loss of sensation.
- Suspected presence of an occult tumour: when clinical symptoms suggest the possibility of an underlying cancer, particularly small-cell lung cancer or breast cancer.
- Monitoring tumour recurrence: The anti-amphiphysin antibody test can help detect the recurrence of a previously diagnosed tumour.
List of Parameters Considered During the Anti-Amphiphysin Antibody Test
The anti-amphiphysin antibody test specifically measures the presence and levels of autoantibodies directed against the amphiphysin protein in the serum. The key parameter considered during this test is:
- Presence of anti-Amphiphysin antibodies: A positive result indicates the presence of autoantibodies targeting the amphiphysin protein, suggesting an autoimmune response often associated with paraneoplastic neurological syndromes and certain cancers.
Anti-Amphiphysin Antibody Test Preparation
To ensure accurate results, proper preparation for the anti-amphiphysin antibody test is essential. The following steps should be followed:
- Specimen Collection: A healthcare professional will collect a blood sample, typically drawn from a vein in the arm, into a serum separator tube (SST).
- Centrifugation: The collected blood sample should be centrifuged within 2 hours of collection to separate the serum from the blood cells.
- Storage: The separated serum should be transferred to a suitable transport tube and stored according to the laboratory's requirements. It can be stored at ambient temperature for up to 24 hours, refrigerated for up to 2 weeks, or frozen for longer periods.
- Fasting or dietary restrictions: There are no specific fasting or dietary restrictions required for the anti-amphiphysin antibody test.
Anti-Amphiphysin Antibody Test Results & Interpretation
The results of the anti-amphiphysin antibody test are typically reported as either positive or negative, indicating the presence or absence of anti-amphiphysin antibodies in the serum. The interpretation of the results is as follows:
- Positive Result: A positive result indicates the presence of anti-amphiphysin antibodies, suggesting the possibility of paraneoplastic neurological syndromes or underlying cancers such as small-cell lung cancer or breast cancer.
- Negative Result: A negative result does not entirely rule out the presence of other autoimmune or neurological conditions but indicates that anti-amphiphysin antibodies are not detected in the serum.
- Clinical Correlation: The test results should be interpreted in the context of the individual's clinical symptoms and other diagnostic findings. The presence of anti-amphiphysin antibodies is not specific to a single type of tumor or neurological syndrome and can be associated with various conditions.
Home Collection for Anti-Amphiphysin Antibody Test Near You
Metropolis Healthcare offers a convenient home collection service for the anti-amphiphysin antibody test, ensuring a seamless experience for patients. A trained phlebotomist will visit your home to collect the blood sample, maintaining the highest standards of safety and sample handling.
This service eliminates the need to visit a diagnostic center, providing comfort and accessibility. With Metropolis Healthcare's commitment to delivering reliable and timely results, you can trust that your anti-amphiphysin antibody test will be processed accurately, empowering you to take proactive steps in managing your health.
By bringing quality diagnostic solutions to your doorstep, Metropolis Healthcare aims to make healthcare more accessible and convenient for everyone.
Amphiphysin Antibody Neuronal Ag in Paraneoplastic Syndrome Serum Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Amphiphysin Antibody Neuronal Ag in Paraneoplastic Syndrome Serum with a clear pricing structure.
The Amphiphysin Antibody Neuronal Ag in Paraneoplastic Syndrome Serum Price in Mumbai is ₹ 4,980 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
This test measures the presence of amphiphysin antibodies in your blood. The test provides critical information to help diagnose and monitor paraneoplastic neurological syndromes caused by underlying cancer.
- To diagnose and monitor paraneoplastic neurological syndromes caused by underlying cancer,
- To detect the presence of antibodies in patients with stiff-person syndrome, an autoimmune disorder that affects muscle rigidity,
- To evaluate the risk of developing other autoimmune disorders, including some types of encephalitis, a condition that causes inflammation in the brain.
This test is recommended for the following reasons:
- When you show symptoms suggestive of an autoimmune or paraneoplastic disorder,
- If you have certain types of cancer that cause neurological disorders
- If you have been diagnosed with a paraneoplastic or autoimmune condition that affects the nervous system.
Higher levels of Amphiphysin antibody may indicate the presence of a neurological disorder or underlying cancer.
Here’s what you should expect during this test:
- A healthcare professional will collect a small sample of blood from your vein,
- The blood sample will be sent to a laboratory for analysis.
There are no specific guidelines for preparations for this test. However, we recommend consulting your physician to receive guidelines specific to your medical history.
- Autoimmune encephalitis panels: These blood tests measure several types of antibodies present in patients with autoimmune encephalitis, a condition causing inflammation in the brain.
- Cancer antigen tests: These blood tests measure the levels of cancer antigens in your blood to detect the presence of certain types of cancer.
Anti-Amphiphysin Antibody Test.
Paraneoplastic neurological syndromes (PNS) are caused by immune response to cancer in the body. PNS can affect the nervous system and cause memory loss, coordination problems, eye movements, muscle weakness, and other neurological issues.
The Anti-Amphiphysin Antibody Test is a diagnostic tool that detects the presence of anti-amphiphysin antibodies in the blood. These antibodies are associated with certain paraneoplastic neurological syndromes and various types of cancers, such as small-cell lung cancer and breast cancer.
Metropolis Healthcare offers a convenient home collection service for the Anti-Amphiphysin Antibody Test, ensuring a seamless experience for patients. A trained phlebotomist will visit your home to collect the blood sample, maintaining the highest standards of safety and sample handling.
The Anti-Amphiphysin Antibody Test is a qualitative test, meaning it indicates the presence or absence of anti-amphiphysin antibodies rather than providing a numerical value. A negative result suggests the absence of these antibodies, while a positive result indicates their presence.
The Anti-Amphiphysin Antibody Test is used to diagnose paraneoplastic neurological syndromes, detect occult tumors, and monitor tumor recurrence. It is particularly useful in cases of stiff-person syndrome, paraneoplastic encWhat will be the total TAT in hours and days if -ephalomyelitis, and sensory neuronopathy, which may be associated with underlying cancers.
The frequency of the Anti-Amphiphysin Antibody Test depends on your clinical condition and your doctor's recommendation. It is typically performed when there are clinical suspicions of paraneoplastic neurological syndromes or underlying cancers. Follow your healthcare provider's advice regarding the timing of the test.
The timing of the Anti-Amphiphysin Antibody Test is not critical. However, it is essential to follow your healthcare provider's instructions and schedule the test based on their recommendation and your clinical condition.
No, fasting is not required for the Anti-Amphiphysin Antibody Test. You can proceed with the test without any specific dietary restrictions or fasting requirements.
Apart from ensuring that the blood sample is handled and stored correctly to maintain its integrity, there are no specific precautions required before undergoing an Anti-Amphiphysin Antibody Test.
The Anti-Amphiphysin Antibody Test specifically measures the presence of anti-amphiphysin antibodies in the serum. These antibodies are associated with paraneoplastic neurological syndromes and certain types of cancer. The test provides a qualitative result indicating the presence or absence of these antibodies.
An Anti-Amphiphysin Antibody Test should be performed when there are clinical indications of paraneoplastic neurological syndromes or when an underlying tumor is suspected.
The blood collection process for the Anti-Amphiphysin Antibody Test is relatively quick and can be completed within a few minutes. However, the analysis of the sample may take 2–6 days, depending on the laboratory's procedures and workload.
The turnaround time for Anti-Amphiphysin Antibody Test reports may vary depending on the laboratory. Typically, the results are available within a week based on the day/time when the sample is collected and processed.
Ratings & Reviews (0)
Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
WhatsApp
