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Allergy - Drug Panel ( Maxi )

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Drug Allergy Test Overview

An allergy is a hypersensitivity disorder of the immune system that causes undesirable reactions to certain substances like food, dust, pollen, drugs or even animal dander. These reactions normally do not occur in others. The substance causing the reaction is an allergen. Immunoglobin E is an antibody that the body produces in case of an allergic reaction. Total IgE test is a blood test used to measure the complete IgE levels in the blood, but it does not indicate what is the specific allergen causing the reaction. Allergy-Drug Panel is an allergy screening that tests the body's interaction to 9 commonly used drugs using the ELISA technique. Based on the results the source of allergy/allergies is determined and the course of treatment is decided accordingly. Along with this the allergen specific IgE levels and are also checked. 

A drug allergy is an allergic reaction to certain medications. The allergic reaction occurs when the immune system, which is designed to fight foreign invaders (allergens) like viruses, bacteria, dust, etc, mistakenly perceives medication as a threat.

In such a situation, the immune system produces Immunoglobulin E (IgE) antibodies. IgE antibodies will trigger the mast cells present in the skin, the lining of the intestine, and air passage to release a large amount of a chemical called histamine, which causes allergic symptoms such as itching, sneezing, running nose, coughing, diarrhoea, and hives.

This reaction to certain medications can be immediate or may be delayed. However, drug allergy is not common to everyone.

Allergy-Drug Panel ( Maxi ) test is done to identify the precise source of suspected allergies brought on by an allergen.

Who should do the Allergy-Drug Panel (Maxi) test?

The symptoms of drug allergy can be mild to life-threatening. Serious drug allergies can occur within an hour after taking the medication. In some cases, symptoms like skin rash can take days or weeks to develop. People with the following symptoms of a drug allergy should do the test:

  • Hives.
  • Skin rash.
  • Itching.
  • Fever.
  • Runny nose.
  • Itchy watery eyes.
  • Swelling.

Anaphylaxis is a rare but life-threatening reaction to drugs or other allergens. People with the following symptoms of anaphylaxis should do the test:

  • Trouble breathing
  • Nausea
  • Abdominal cramps
  • Vomiting
  • Diarrhoea
  • Irregular heartbeat
  • Drop in blood pressure
  • Seizure
  • Dizziness or lightheadedness
  • Loss of consciousness

Written by: Dr.Shibani R, Medical Writer, Medical Affairs

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Allergy - Drug Panel ( Maxi ) Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Allergy - Drug Panel ( Maxi ) with a clear pricing structure.

The Allergy - Drug Panel ( Maxi ) Price in Mumbai is ₹ 7,500 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Drug allergy test is done in suspected allergies to specific medications or drugs to determining the exact drug component causing the allergic reaction. Common symptoms are: Itching, running nose, sneezing, coughing, diarrhoea, hives. Certain severe cases may also lead to anaphylactic shock. Based on these results further specific testing is recommended. The test is important prior to prescribing medications to these patients.

Allergy-Drug Panel is an allergy screening test done:

  • To measure the IgE-mediated response to 9 commonly used drugs such as cocaine, morphine, amphetamine, methamphetamine, barbiturates, methadone, phencyclidine (PCP), benzodiazepine, and marijuana through ELISA (Enzyme-Linked Immunosorbent Assay) technique.
  • To identify the precise source of suspected allergies brought on by specific sources of inhalant dust allergen.
  • To determine the exact drug component that is causing an allergic reaction.
  • To evaluate the allergen behind the anaphylactic shock.

Drug allergy test measures the IgE mediated response to 9 common drug components. Total IgE levels are also measured. Further tests to a specific allergen will help in further diagnosis.

Drug allergy test requires a blood sample post exposure to the drug panel. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer. 

Positive result to a particular allergen indicates that the person is allergic to that particular drug. The same must be communicated to any doctor prior to prescribing medicines for these patients. Increased allergen-specific IgE levels further confirms that. If a medicine with the allergic drug component is consumed, it may even trigger adverse drug reactions which may often prove fatal. Hence, caution is required. Very often the test may be positive for more than one allergen as well. The further treatment course is decided based on the results.

In the case of mild allergy, if your allergy symptoms last for longer than two weeks and are recurring, you should consult your doctor. The doctor may recommend an allergy drug test getting done.

In case of immediate allergic reaction to drugs or other allergens which results in troubled breathing, increased heart beat etc, you should consult your doctor immediately. Based on your condition, your doctor may recommend allergy panel screening.

Not always. In some cases, the symptoms of a drug allergy may be mild and go away. However, in other cases, it can be life-threatening if it causes symptoms such as swelling, irregular heartbeat, difficulty in breathing, and unconsciousness 

Drugs such as penicillin, ibuprofen, carbamazepine, trastuzumab, and docetaxel may cause allergic reactions in some people.

Drug reactions can occur immediately within an hour or may take days or weeks to develop

You need no special precaution to undergo an allergy test. However, in certain cases, your doctor may ask you to fast before a test. Inform your doctor if you are taking medications before taking an allergy test.

Reference:

1.https://www.healthline.com/health/drug-allergy#symptoms

2.https://www.1mg.com/labs/test/drug-of-abuse-panel-9-1679

3.https://my.clevelandclinic.org/health/diseases/8621-medication-allergies

4.https://www.mayoclinic.org/diseases-conditions/drug-allergy/symptoms-causes/syc-20371835

  • IgE Drug Allergy Test.
  • Drug Panel Test.
  • Drug Allergy Test.
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