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Allergy Component Testing (CRD)

Also known as: Allergy Panel - CRD (Component Testing)

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Allergy Component Testing (CRD) Overview

Allergy Component Testing (CRD) is an advanced allergy test that identifies specific protein components within allergens responsible for triggering allergic reactions. It provides a detailed, accurate understanding of an individual's allergy profile, enabling better diagnosis and personalised treatment plans.

An allergy is a hypersensitivity disorder of the immune system that causes undesirable reactions to certain substances like food, dust, pollen, drugs or even animal dander. These reactions normally do not occur in others. The substance causing the reaction is an allergen. Immunoglobin E is an antibody that the body produces in case of an allergic reaction. This CRD test, by using the latest nanotechnology and artificial intelligence, can easily detect specific IgE antibodies against nearly 295 different components of allergens, using a simple blood test and provides results for 158 food allergens, 127 respiratory allergens and 10 contact allergens. CRD allows for a more accurate allergen immunotherapy (AIT) screening.

Written by - Dr. Shibani R, Medical Writer, Medical Affairs

Reasons for Undergoing the Allergy Component Testing (CRD)

There are several reasons why individuals should consider undergoing the CRD allergy test:

  • Precise Diagnosis: CRD offers a more accurate identification of the specific protein components within allergens that cause reactions, which is particularly useful when traditional tests are inconclusive or when differentiating between cross-reactive allergens is necessary.
  • Personalised Treatment: By identifying the exact proteins responsible for the allergic reaction, CRD helps in developing targeted therapies and reducing the risk of severe allergic reactions.
  • Predicting Clinical Risk: CRD allergy testing can predict the evolution of the allergic process and the clinical risk associated with each patient, helping in stratifying the outcome of oral food challenges (OFC).
  • Improved Quality of Life: By providing detailed insights into the allergenic components, CRD enhances the overall quality of life for individuals with allergies by allowing for more precise management and treatment strategies.

List of Parameters Considered During the Allergy Component Testing (CRD)

During the CRD test, the levels of specific IgE antibodies against various protein components of an allergen are measured. Some examples of these parameters include storage proteins (e.g., Ara h 1, 2, 3, 6 for peanuts), PR-10, LTP, Profilin, and CCDs.

Allergy Component Testing (CRD) Preparation

Preparation for the CRD allergy test is relatively straightforward. Generally, no special preparation or fasting is required for the CRD test. Inform your healthcare provider about any medications you are taking. The test involves a simple blood sample collection.

Allergy Component Testing (CRD) Results & Interpretation

The results of the CRD test are interpreted based on the levels of specific IgE antibodies against the various protein components of the allergen:

  • Report Breakdown: The report will break down the results into the proteins for each allergen being tested, providing measurements in kU/L (kilo units of allergen per liter).
  • Clinical Interpretation: The results should be interpreted by a healthcare provider who can explain which proteins you are sensitized to and the associated clinical risks. For example, sensitization to certain proteins like Ara h 1, 2, 3, and 6 may indicate a higher risk of severe reactions, while others like Ara h 8 might suggest milder reactions.
  • Guidance on Management: Based on the results, your healthcare provider can guide you on the best course of action, including dietary changes, avoidance strategies, and potential oral food challenges.

Home Collection for Allergy Component Testing (CRD)

Metropolis Healthcare offers a convenient home sample collection service for the CRD allergy test, ensuring comfort and safety for patients. A trained phlebotomist will come to your doorstep to collect the blood sample, maintaining high standards of sample handling without compromising on testing accuracy. With timely and reliable results, Metropolis Healthcare is committed to making healthcare accessible by providing quality diagnostic solutions conveniently at home.

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Allergy Panel - CRD (Component Testing) Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Allergy Panel - CRD (Component Testing) with a clear pricing structure.

The Allergy Panel - CRD (Component Testing) Price in Fort is ₹ 21,000 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

This is an AI based test to detect the antibodies against 158 food allergens, 127 respiratory allergens and 10 contact allergens.

  • This test helps in improved diagnosis of patients suffering from IgE-mediated diseases and the selection of patients for allergen immunotherapy.
  • The test also helps in the prognosis and understanding of cross-reactivity.
  • To differentiate between primary allergen sensitisation and reaction to cross-reacting components.
  • It can also help establish the patient’s allergy to components of different food items allowing the rest of the food to be consumed and in some cases allowing consumption of allergic components after heat treatment (food component specific).
  • Patients with suspected allergies showing common symptoms like itching, running nose, sneezing, coughing, diarrhoea, hives
  • Those with suspected parasitic or fungal infections.
  • Certain autoimmune disorders.

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

 

There are no specific preparations required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.

Presence of antibodies to specific IgE may indicate allergy positivity as well as cross reactivity to certain allergens.

The allergy component test, or CRD test, is an advanced method of allergy testing that identifies specific protein components within allergens responsible for triggering allergic reactions.

Metropolis Healthcare offers a convenient home sample collection service for the CRD allergy test, ensuring comfort and safety for patients. A trained phlebotomist will come to your doorstep to collect the blood sample, maintaining high standards of sample handling without compromising on testing accuracy.

The CRD test is used to provide precise diagnosis, personalised treatment, predict clinical risk, and improve quality of life for individuals with allergies.

In the CRD allergy test, results are measured in kU/L, and interpretation depends on the specific proteins and their associated clinical risks.

Anyone experiencing allergic symptoms or suspected of having allergies, especially those where traditional tests are inconclusive, is eligible for the CRD test.

The benefits of the CRD allergy test include precise diagnosis, personalised treatment, prediction of clinical risk, and improved quality of life for individuals with allergies.

You should get the CRD test as advised by your healthcare provider, typically when symptoms change or when reassessment is necessary.

You can get the CRD allergy test done at any time, as no special preparation is required.

No, fasting is not required for the CRD test.

Apart from informing your healthcare provider about any medications you are taking, no other specific precautions are needed before getting the CRD allergy test.

The CRD test measures specific IgE antibodies against various protein components of an allergen, such as storage proteins, PR-10, LTP, profilin, and CCDs.

The CRD allergy test is done by collecting a blood sample, which is then analysed for specific IgE antibodies against various allergenic components.

The CRD test should be done when advised by your healthcare provider, especially if you are experiencing allergic symptoms or when traditional allergy tests are inconclusive.

The CRD allergy test becomes positive when specific IgE antibodies against allergenic components are detected above a certain threshold, indicating sensitisation to those components.

The blood sample collection for the CRD test takes only a few minutes. However, the analysis and processing of the sample may take a few days.

The turnaround time for CRD allergy test reports may vary depending on the lab location as well as other factors. Typically, results are available within 24 hours after the sample is collected.

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