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AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT - Pure Culture
Also known as: AFB Drug Susceptibility Panel - 1st Line (4 drugs) SIRE, Pure Culture
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Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
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AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT Overview
The "AFB Drug susceptibility - 1st Line (4 drugs) SIRE panel by MGIT - Pure Culture" test is a vital diagnostic tool for tuberculosis (TB) treatment. It utilizes the MGIT (Mycobacteria Growth Indicator Tube) method on pure cultures of Mycobacterium tuberculosis (MTB) Complex to assess the drug susceptibility of MTB to four first-line anti-tuberculosis drugs: Streptomycin, Isoniazid, Rifampicin, and Ethambutol. The test's clinical utility lies in providing essential information to healthcare professionals about the effectiveness of these drugs against the MTB Complex causing TB, guiding the formulation of targeted and effective treatment regimens. Early detection of drug resistance through this test allows for timely adjustments in the treatment plan, ensuring optimal care and increasing the chances of successful TB treatment. Overall, this test significantly contributes to personalized TB treatment, improving patient outcomes, and supporting efforts to combat tuberculosis effectively.
The AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT - Pure Culture is a crucial diagnostic test that determines the susceptibility of the bacteria responsible for tuberculosis (TB), specifically the Mycobacterium tuberculosis (MTB) complex, to four first-line anti-tuberculosis drugs. This test employs the Mycobacteria Growth Indicator Tube (MGIT) method on pure cultures of MTB to assess the effectiveness of streptomycin, isoniazid, rifampicin, and ethambutol in treating the patient's specific TB strain.
By evaluating the growth of MTB in the presence of these drugs, doctors can tailor treatment regimens to the individual patient's needs, ensuring optimal outcomes and reducing the risk of treatment failure. This test is essential for managing drug-resistant TB cases and plays a vital role in controlling and preventing the spread of TB within communities.
Reasons for Undergoing the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT - Pure Culture
There are several important reasons why a doctor may recommend the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT - Pure Culture:
- To guide tuberculosis treatment by determining which drugs will be effective against the infection
- To identify any drug resistance, which is crucial for managing and treating TB effectively
- In cases of lack of response to initial treatment, treatment failure, or relapse
- For patients with risk factors for drug-resistant tuberculosis
- To guide appropriate treatment selection in multidrug-resistant tuberculosis cases
List of Parameters Considered During the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT
The AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT - Pure Culture test assesses the following key parameter:
- Growth of MTB in the Presence of Drugs: The test evaluates the ability of the MTB bacteria to grow in the presence of each of the four first-line drugs: streptomycin, isoniazid, rifampicin, and ethambutol. If the bacteria grow despite the presence of a drug, it indicates resistance to that specific drug. Conversely, if the bacteria do not grow, it suggests susceptibility to the drug in question.
AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT Preparation
To prepare for the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT - Pure Culture, there are a few important steps to follow:
- Inform Your Doctor: Provide your doctor with information about any medications you are currently taking.
- Medical History: Share your complete medical history, including details of any previous TB treatment.
- Follow Instructions: Adhere to any specific instructions provided by your doctor, such as fasting requirements or discontinuing certain medications.
- Sample Collection: A trained professional will collect a sample of the MTB complex from your body, typically through sputum or other bodily samples, for testing.
AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT Results & Interpretation
The results of the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT - Pure Culture indicate whether the MTB is susceptible or resistant to each of the four first-line drugs:
- Susceptible: If the bacteria do not grow in the presence of a drug, it indicates that the patient's TB is susceptible to that specific drug.
- Resistant: If the bacteria grow despite the presence of a drug, it suggests resistance to that particular drug.
- Interpretation: These results are essential for guiding the treatment regimen. If the bacteria are resistant to any of the first-line drugs, the patient may require treatment with second-line drugs or a combination of drugs tailored to their specific resistance profile.
Home Collection for AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT
Metropolis Healthcare offers a convenient home sample collection service for the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT - Pure Culture. A trained phlebotomist will visit your home to collect the necessary samples, ensuring comfort, safety, and high standards of sample handling without compromising testing accuracy. This service allows you to receive timely and reliable results from the comfort of your own home. By making healthcare more accessible, Metropolis Healthcare demonstrates its commitment to providing quality diagnostic solutions conveniently at your doorstep.
AFB Drug Susceptibility Panel - 1st Line (4 drugs) SIRE, Pure Culture Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the AFB Drug Susceptibility Panel - 1st Line (4 drugs) SIRE, Pure Culture with a clear pricing structure.
The AFB Drug Susceptibility Panel - 1st Line (4 drugs) SIRE, Pure Culture Price in Mumbai is ₹ 5,300 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
This test determines the susceptibility of Mycobacterium tuberculosis complex to four drugs: Streptomycin, Isoniazid, Rifampicin, and Ethambutol.
• To guide the treatment of tuberculosis
• To determine which drugs will be effective against the infection
• To identify any drug resistance
• To ensure appropriate drug selection for effective management and prevention of further spread
This test is recommended when tuberculosis infection is suspected or diagnosed. It is particularly useful in the following situations:
• When there is a lack of response to initial treatment
• In cases of treatment failure or relapse
• For patients with risk factors for drug-resistant tuberculosis
• To guide appropriate treatment selection in multidrug-resistant tuberculosis cases
Abnormal results may indicate resistance to one or more drugs, which can impact treatment effectiveness.
During this test, a healthcare professional will collect a sample of the Mycobacterium tuberculosis (Mtb) complex from your body. They will send the sample for analysis using the MGIT (Mycobacteria Growth Indicator Tube) method.
• Follow any specific instructions provided by your healthcare provider regarding fasting or medication restrictions.
• Inform your doctor if you have any specific requirements.
• Acid-fast bacilli staining: To detect the presence of Mycobacterium tuberculosis in sputum or other samples
• GeneXpert MTB/RIF assay: To simultaneously detect TB and rifampicin resistance
First-line anti-tuberculosis drug susceptibility panel
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis bacteria. It primarily affects the lungs but can also affect other organs. Common symptoms include persistent cough, weight loss, night sweats, and fatigue. Early detection and appropriate treatment are essential for successful management.
The AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT is a diagnostic test that determines the susceptibility of Mycobacterium tuberculosis complex to four first-line anti-tuberculosis drugs - streptomycin, isoniazid, rifampicin, and ethambutol - using the Mycobacteria Growth Indicator Tube (MGIT) method on pure cultures.
Yes, home sample collection is available for certain drug susceptibility tests, including the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE by MGIT. Be sure to inform your healthcare provider about any medications you are currently taking.
The normal result for the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT is when the Mycobacterium tuberculosis complex is found to be susceptible to all four first-line drugs tested. Resistance to any of the drugs indicates an abnormal result.
The AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT is used to guide tuberculosis treatment by determining drug susceptibility, identifying drug resistance, and ensuring appropriate drug selection for further spread of the disease.
The frequency of testing for the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT depends on clinical necessity. It is typically performed when tuberculosis infection is suspected, or during treatment to monitor drug resistance.
The timing of the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT is based on clinical need and is usually performed when tuberculosis is suspected or diagnosed, or during the course of treatment to assess drug resistance and guide appropriate therapy.
Fasting is not typically required for the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT. However, follow any specific instructions provided by your doctor.
Before getting tested for the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT, inform your doctor about any medications you are currently taking and provide your complete medical history.
The AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT includes parameters that assess the susceptibility of the Mycobacterium tuberculosis complex to four first-line anti-tuberculosis drugs: streptomycin, isoniazid, rifampicin, and ethambutol.
The AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT should be performed when tuberculosis infection is suspected or diagnosed, in cases of lack of response to initial treatment, treatment failure, or relapse, and for patients with risk factors for drug-resistant tuberculosis.
The AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT typically takes several weeks to complete. The exact time may vary depending on the laboratory and the growth rate of the bacteria.
The turnaround time for the AFB Drug Susceptibility Panel 1st Line (4 Drugs) SIRE By MGIT reports may vary depending on the lab and the complexity of the case. Typically, results are available within 4 weeks based on the day/time when the sample was collected and processed.
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