Actitest and Fibrotest

Actitest and Fibrotest measure the concentration of specific proteins in your blood that indicate liver fibrosis or inflammation. These proteins include SGPT (serum glutamic-pyruvic transaminase), Bilirubin, GGTP (gamma-glutamyl transpeptidase), Alpha2 Macroglobulin, Apo A1, and Haptoglobulin with graph.

• To diagnose liver diseases such as hepatitis B or C • To evaluate the progression of liver fibrosis • To monitor liver injury or damage caused by alcoholism, obesity, or other factors • To assess the effectiveness of treatment for liver disease • To determine the risk of developing end-stage liver disease

Actitest and Fibrotest are recommended when • you have a history of liver disease or risk factors such as obesity, heavy drinking, or exposure to hepatitis B or C, • you have abnormal liver function tests indicating possible liver damage, or • you are undergoing treatment for liver disease or monitoring the efficacy of previous treatment.

Abnormal results may indicate liver inflammation or fibrosis, but further tests are needed to confirm the diagnosis.

• A healthcare professional will clean your skin with an antiseptic solution and insert a needle into your vein. • They will draw a small amount of blood into a tube which will be sent for testing.

You should inform your doctor about any medications or supplements you’re taking that might affect the test results. Inform your doctor if you have any specific requirements. You may be asked to fast for a few hours before the test.

• Liver function tests to assess liver enzymes • Viral hepatitis testing to determine if you have hepatitis B or C

Non-invasive markers of liver fibrosis

Liver fibrosis is the gradual accumulation of scar tissue in the liver, caused by chronic inflammation or injury. It can lead to cirrhosis or irreversible liver damage if left untreated.

Actitest and Fibrotest are non-invasive blood tests that help assess liver fibrosis and inflammation. They measure specific serum biomarkers to evaluate the severity of liver disease, providing an alternative to liver biopsy for diagnosing and monitoring liver conditions.

Home sample collection is generally not recommended for Actitest and Fibrotest due to the need for immediate processing and light protection of the specimen. It is best to have the blood drawn in a clinical or laboratory setting to ensure accurate results.

Normal levels for Actitest and Fibrotest are indicated by scores: F0 (no fibrosis) for Fibrotest and A0 (no activity) for Actitest. Specific numerical ranges are provided in the reports, but these scores are the primary indicators of normal or abnormal results.

Actitest and Fibrotest are used to diagnose and monitor liver diseases, evaluate the progression of liver fibrosis, assess treatment effectiveness, and determine the risk of developing end-stage liver disease. They are particularly useful for individuals with risk factors or abnormal liver function tests.

The frequency of testing for Actitest and Fibrotest depends on your specific condition and the advice of your doctor. Periodic testing may be recommended for those undergoing treatment or with ongoing risk factors for liver disease.

Several factors can affect the Actitest and Fibrotest results, including chronic haemolysis, Gilbert disease, use of certain medications like protease inhibitors in HIV treatment, and conditions that alter the levels of the biomarkers measured, such as acute inflammation or renal insufficiency.

Yes, certain medications, such as protease inhibitors used in HIV treatment, can increase levels of some biomarkers, affecting the Actitest and Fibrotest results. Consult with your doctor to interpret results accurately in such cases.

There is no specific time requirement for the Actitest and Fibrotest; however, the blood sample should be collected and handled promptly to protect it from light.

Fasting is not typically required for the Actitest and Fibrotest, but it is important to follow any specific instructions provided by your doctor or laboratory.

Before getting tested for Actitest and Fibrotest, ensure that the blood sample is protected from light and processed immediately to prevent degradation of the biomarkers. Follow any specific instructions provided by the laboratory or doctor for optimal results.

The parameters included in Actitest and Fibrotest are gamma-glutamyltransferase (GGT), total bilirubin, alpha-2-macroglobulin, apolipoprotein A1, haptoglobin, and alanine aminotransferase (ALT). These biomarkers are used to assess liver fibrosis and inflammation.

Actitest and Fibrotest should be done when recommended by your doctor, usually if you have a history of liver disease, risk factors such as obesity or heavy drinking, or abnormal liver function tests indicating possible liver damage.

The blood sample collection for the Actitest and Fibrotest typically takes only a few minutes. However, the sample needs to be centrifuged within 2 hours of collection and then sent to the laboratory for analysis, which may take a few days.

The turnaround time for Actitest and Fibrotest reports may take a week, depending on the day/time of sample collection and processing.