Sickling Test

The Sickling Test measures haemoglobin S levels in the blood to detect sickle cell disease, a genetic disorder affecting red blood cells. Identifying haemoglobin S is crucial in diagnosing and monitoring sickle cell anaemia and its complications.

• To identify sickle cell trait or sickle cell disease.
• To diagnose the cause of unexplained pain, fatigue, or jaundice.
• To assess the risk of complications like pain crises and organ damage.
• To guide treatment strategies for individuals with sickle cell disease.

Doctors recommend the sickling test if you:

• Experience symptoms like severe pain, fatigue, or jaundice.
• Have a family history of sickle cell disease.
• Need to assess your risk of developing complications from sickle cell disease.

Abnormal results may indicate sickle cell trait or sickle cell disease. Conditions such as severe anaemia, pain crises, and organ damage can be tentatively linked to abnormal results. Discuss your results with your doctor for a comprehensive evaluation.

During the sickling test:

• A small amount of blood is drawn from a vein in your arm.
• The blood sample is analysed for the presence of sickle haemoglobin.
• The procedure is quick and generally painless.

Before the test:

• No special preparations are needed.
• Inform your doctor about any medications you are taking.
• Stay relaxed during the test to ensure an accurate result.
• Follow the specific instructions from your healthcare provider.

Other tests that may accompany the sickling test include:

• Complete Blood Count (CBC): Assesses red and white blood cell levels.
• Haemoglobin Electrophoresis: Identifies various types of haemoglobin in your blood.
• Peripheral Blood Smear: Examines blood cells for abnormalities under a microscope.

Sickle Cell Screen or Sickle Cell Solubility Test

Sickle Cell Disease is an inherited blood disorder where red blood cells become rigid and sticky, causing blockages in blood vessels that can lead to pain, infections, organ damage, and stroke.