Peripheral Smear Examination (PBS)
Also known as: PBS (Peripheral smear Examination), EDTA Blood
PBS (Peripheral smear Examination), EDTA Blood Details in Brief
| Also Known As | PBS (Peripheral Smear Examination), Peripheral Blood Film (PBF), Blood Smear Analysis, Manual Differential |
|---|---|
| Purpose | Microscopic evaluation of blood cell morphology to aid in diagnosing anaemia, leukaemia, and blood disorders |
| Preparation | No special preparation required |
| Fasting | Not required |
| Reporting Time | After 4 hours |
| Cost | 320 |
What Is a Peripheral Smear Test?
A peripheral smear test, or blood smear test, is a laboratory examination where a drop of your blood is spread thinly across a glass slide, stained with special dyes, and examined under a microscope by a trained pathologist. This test provides detailed visual information about the shape, size, and structure of your blood cells that automated machines cannot detect.
This peripheral smear examination helps detect and diagnose various blood disorders, including different types of anaemia, infections like malaria, blood cancers such as leukaemia, and other blood-related health conditions.
What Does the Peripheral Smear Test Measure?
The peripheral smear examination performs a detailed visual evaluation of your blood cells to assess their quality and appearance:
- Red Blood Cell Analysis: Examines size, shape, colour, and overall morphology to help identify types of anaemia, including iron deficiency and haemolytic anaemia.
- White Blood Cell Assessment: Identifies different types of white blood cells and detects abnormal or immature cells that may indicate infections or blood cancers.
- Platelet Evaluation: Estimates platelet numbers and observes their size to assess bleeding or clotting risks.
- Parasite Detection: Searches for blood parasites, particularly important for diagnosing malaria and other parasitic infections common in India.
Peripheral Smear Test: Who Needs It and Why It's Done
What Symptoms May Call for a Peripheral Smear Test?
Your doctor may recommend the blood smear test if you experience persistent symptoms that could indicate a blood disorder:
- Unexplained fatigue, weakness, or constant tiredness
- Pale skin (pallor) or yellowish skin colour (jaundice)
- Frequent or recurring infections
- Unexplained fever, especially with chills
- Easy bruising or bleeding that's difficult to stop
- Unexplained weight loss
- Bone and joint pain
- Enlarged lymph nodes, spleen, or liver
Who Should Get a Peripheral Smear Test?
Several groups of people may benefit from this important blood examination:
- Patients with concerning symptoms experiencing the warning signs listed above
- Follow up patients whose Complete Blood Count (CBC) results showed abnormal findings
- High-risk individuals with a family history of genetic blood disorders like sickle cell anaemia or thalassaemia.
- Patients on specific medications requiring monitoring of bone marrow function, such as those receiving chemotherapy.
- Suspected infection cases, particularly when malaria or other parasitic infections are possible.
Why Is a Peripheral Smear Test Done?
A peripheral smear test provides crucial visual details about your blood cells that automated tests cannot capture. It helps doctors confirm diagnoses, identify specific causes of blood abnormalities, and monitor treatment effectiveness.
Importance of a Peripheral Smear Test
The peripheral smear test serves as a vital diagnostic tool that complements modern automated blood testing. It provides definitive visual evidence that can pinpoint exact causes of blood disorders, such as identifying sickle-shaped cells in sickle cell anaemia or detecting malaria parasites. The test acts as a quality check on automated results, with expert pathologists providing nuanced interpretations that guide treatment decisions.
For patients with blood cancers or those undergoing chemotherapy, regular peripheral smear examinations help monitor disease progression and treatment response, making it an essential component of a comprehensive blood health assessment.
Peripheral Smear Test Booking & Reports – Metropolis Healthcare India
How to Book a Peripheral Smear Test?
- Simple Online Booking
Booking can be done through the Metropolis Healthcare App or website. Select the 'Peripheral Smear Examination', choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab. - Safe Home Sample Collection
Our trained phlebotomists ensure the timely collection of your sample while strictly following all safety and hygiene protocols. - Sample Tracking Updates
Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website. - Accurate Laboratory Testing
Your sample is processed at our NABL- & CAP-accredited laboratories, where expert technicians ensure accurate results. - Quick & Easy Reports
Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is Home Sample Collection for the Peripheral Smear Test Available Near You?
Yes, home blood sample collection is available for peripheral smear examination nationwide through Metropolis Healthcare. Our trained phlebotomists visit your home at your preferred time, following strict safety protocols to collect your blood sample. This service ensures you receive the same accurate, reliable results from our NABL- & CAP-accredited pathology lab network without the need to travel.
How Long Does It Take to Get a Peripheral Smear Test Report?
Reports are usually available after 4 hours once the sample reaches the lab.
Note: Reporting time and cost may vary depending on your location.
Where Can I See or Get the Peripheral Smear Test Results?
Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.
Interpreting Peripheral Smear Test Results
The following table explains what different findings in your peripheral smear test may indicate:
|
Parameter |
Normal Findings |
Abnormal Findings May Indicate |
|
RBC Morphology |
Normal size, shape, and colour |
Hypochromasia, microcytosis, and anisocytosis may suggest iron deficiency anaemia or other blood disorders. |
|
WBC Count & Types |
Normal differential count with mature cells |
Abnormal counts or atypical cells may indicate infections, leukaemia, or immune disorders. |
|
Platelets |
Adequate numbers on smear |
Low numbers suggest bleeding risk; high numbers may indicate clotting disorders. |
|
Haemoparasites |
Not seen on smear |
Presence indicates parasitic infections like malaria or filariasis. |
Conditions that May Affect Peripheral Smear Test Accuracy
Several factors can influence your peripheral smear test results and should be discussed with your healthcare provider:
- Severe dehydration can cause blood cells to appear more concentrated than they actually are.
- Certain medications, including blood thinners, antibiotics, and chemotherapy drugs, may affect cell appearance.
- Recent blood transfusions can show mixed cell populations that may complicate interpretation.
- Sample handling issues, such as delayed processing or improper storage, can affect cell morphology.
- Underlying medical conditions, like kidney disease or liver problems, may influence blood cell characteristics.
- Recent illness or infections can temporarily alter white blood cell patterns and numbers.
How Is a Peripheral Smear Test Done?
The peripheral smear test follows a systematic laboratory process to examine your blood cells:
- A small blood sample (1 ml) is collected in an EDTA tube to prevent clotting.
- A thin layer of blood is spread across a glass slide using a spreader slide.
- The blood film is air-dried and stained with Wright's or Giemsa stain.
- A trained pathologist examines the stained slide under high-powered microscopy.
- Different areas of the slide are systematically reviewed for cell morphology.
- The pathologist counts and identifies various cell types manually.
- Abnormal cells, parasites, or unusual findings are documented and reported.
How Should You Prepare for a Peripheral Smear Test?
Preparing for your peripheral smear test is straightforward and requires minimal effort:
- No fasting required: You can eat and drink normally before the test.
- Continue regular medications: Take your usual medicines unless your doctor specifically advises otherwise.
- Inform about all medications: Tell your healthcare provider about all prescription drugs, supplements, and herbal remedies you're taking.
- Stay well-hydrated: Drink adequate water before your test to ensure proper blood flow.
- Wear comfortable clothing: Choose clothes with sleeves that can be easily rolled up for blood collection.
- Bring medical history: Carry any previous blood test reports or relevant medical records.
Diseases that a Peripheral Smear Test Can Help Detect
The peripheral smear examination can help identify various blood-related conditions and health risks:
- Iron deficiency anaemia and other types of anaemia
- Sickle cell disease and thalassaemia
- Malaria and other parasitic blood infections
- Leukaemia and other blood cancers
- Bacterial and viral infections
- Platelet disorders affecting blood clotting
- Hereditary blood cell abnormalities
- Side effects of medications on blood cells
Peripheral Smear Tests/Packages that You Can Book With Metropolis Healthcare
The following table shows related tests and packages available with Metropolis Healthcare:
|
Test/Package Name |
Purpose/Highlights |
|
Detailed white blood cell analysis for infection and immune system evaluation |
|
|
Assesses blood clotting ability and bleeding risk |
|
|
Focused assessment of eosinophils for allergy and infection diagnosis |
Peripheral Smear Test Prices in Different Cities
The cost of a peripheral smear test may vary depending on your location. Here's a table showing the approximate prices in different cities:
|
City |
Approximate Cost (INR) |
|
₹140 - ₹390 |
|
|
₹140 - ₹390 |
|
|
₹140 - ₹390 |
|
|
₹140 - ₹390 |
|
|
₹140 - ₹390 |
|
|
₹140 - ₹390 |
PBS (Peripheral smear Examination), EDTA Blood Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the PBS (Peripheral smear Examination), EDTA Blood with a clear pricing structure.
The PBS (Peripheral smear Examination), EDTA Blood Price in Mumbai is ₹ 320 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
There is no specific best time for a peripheral smear test. You can take this test at any time of the day that's convenient for you, as timing doesn't affect the results.
No, fasting is not required for a peripheral smear test alone. You can eat and drink normally before the test unless other blood tests requiring fasting are ordered simultaneously.
Yes, severe dehydration can cause blood concentration changes that may affect cell counts and appearance. It's recommended to stay well-hydrated before any blood test for accurate results.
No special dietary preparation is needed. However, inform your doctor about all medications, vitamins, and supplements you're taking, as some drugs can affect blood cell appearance or counts.
A healthcare professional cleans your arm, inserts a sterile needle into a vein, and draws a small blood sample into an EDTA tube. The procedure is quick and minimally uncomfortable.
Risks are minimal and include slight pain at the needle site, minor bruising, or light-headedness. Serious complications, like infection, are extremely rare with proper sterile technique.
A normal peripheral smear report describes blood cells as normal in size, shape, and appearance, with no abnormal cells or parasites seen. Results are descriptive rather than numerical values.
The test is also called Peripheral Blood Film (PBF), Blood Smear Analysis, Manual Differential, or PBS (Peripheral Smear Examination).
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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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