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Ovarian Marker Profile

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Overview

The Ovarian Marker Profile is a blood test that measures several tumor markers, or substances that may indicate the presence of ovarian cancer or other ovarian abnormalities. The profile typically includes the following markers:

  • CA125: This tumor marker is commonly used to monitor ovarian cancer, but it can also be elevated in other conditions such as endometriosis and pelvic inflammatory disease.
  • CEA: Carcinoembryonic antigen (CEA) is a tumor marker that is often used to monitor colorectal cancer, but it can also be elevated in ovarian cancer.
  • CA72.4: This tumor marker is less specific for ovarian cancer than CA125, but it may still be elevated in some cases.
  • HE4: Human epididymis protein 4 (HE4) is a newer tumor marker that is thought to be more specific for ovarian cancer than CA125.
  • ROMA Index: This is a mathematical algorithm that combines the levels of CA125 and HE4 to provide a more accurate assessment of the risk of ovarian cancer in women with a pelvic mass.
  • LDH: Lactate dehydrogenase (LDH) is an enzyme that is often elevated in cancer, but it is not specific for ovarian cancer.

Associated Tests:

Cancer marker profile-Ovarian-Comprehensive

 

Written by: Supriya Kulkarni, Lead-Content & Training

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Ovarian Marker Profile Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Ovarian Marker Profile with a clear pricing structure.

The Ovarian Marker Profile Price in Mumbai is ₹ 4,295 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The Ovarian Marker Profile is typically ordered for women:

  • Who have a suspected ovarian tumor or who are at high risk for ovarian cancer due to family history or other factors.
  • To monitor women with a history of ovarian cancer or other gynecological cancers for recurrence or metastasis.
  • To help diagnose ovarian cancer or other gynecological cancers.
  • To evaluate women with a pelvic mass or other symptoms that may be indicative of ovarian cancer.
  • To screen women who are at high risk for ovarian cancer due to family history or genetic mutations, such as BRCA1 and BRCA2.
  • To monitor the effectiveness of ovarian cancer treatment.
  • To assess the risk of ovarian cancer in women with a pelvic mass, using the ROMA Index.
  • To evaluate women with other gynecological conditions, such as endometriosis, pelvic inflammatory disease, or ovarian cysts.

The Ovarian Marker Profile measures CA125, CEA, CA72.4, HE4, ROMA Index, and LDH.

If the results of an Ovarian Marker Profile is abnormal, it may indicate a variety of conditions, including ovarian cancer or other gynecological cancers, as well as non-cancerous conditions such as endometriosis or pelvic inflammatory disease

The test involves drawing a small amount of blood from a vein in your arm. A healthcare professional will clean the area with an antiseptic, wrap an elastic band around your upper arm to make the veins more visible, and insert a needle into a vein to collect the blood sample. You may feel a brief prick or stinging sensation when the needle is inserted, but the procedure is generally painless.

 

No special preparation is required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.

 

Some possible indications for an Ovarian Marker Profile may include:

  • Symptoms: Women with symptoms that may be indicative of ovarian cancer, such as abdominal pain, bloating, or difficulty eating, may be evaluated using an Ovarian Marker Profile.
  • High risk: Women who are at high risk for ovarian cancer due to family history, genetic mutations, or other factors may be screened using an Ovarian Marker Profile.
  • Pelvic mass: Women with a pelvic mass, particularly if it is suspicious for ovarian cancer, may be evaluated using an Ovarian Marker Profile.
  • Monitoring: Women who have been diagnosed with ovarian cancer or other gynecological cancers may be monitored using an Ovarian Marker Profile to evaluate the effectiveness of treatment or to monitor for recurrence.

In addition to an Ovarian Marker Profile, other blood tests may be ordered to provide additional information or to help rule out other conditions like the hormone tests to evaluate hormone levels in the body, particularly if there are concerns about hormonal imbalances or conditions such as polycystic ovary syndrome (PCOS).

 

  • CA125: Cancer Antigen 125
  • CEA: Carcinoembryonic Antigen
  • CA72.4: Cancer Antigen 72-4
  • HE4: Human Epididymis Protein 4
  • ROMA Index: Risk of Ovarian Malignancy Algorithm Index
  • LDH: Lactate Dehydrogenase

 

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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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