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Leukemia Panel By FISH - AML

Also known as: Leukemia Panel (AML) by FISH, Heparin Bone Marrow

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Overview

The Leukemia Panel by FISH (Fluorescence In Situ Hybridization) for Acute Myeloid Leukemia (AML) is a diagnostic test that examines specific genetic abnormalities including ETO/AML1, PML/RARA, CBFB, and MLL using FISH techniques. These genetic rearrangements serve as prognostic markers, providing valuable information about the disease prognosis and guiding treatment decisions. The ETO/AML1 fusion gene is associated with a favorable prognosis, while the PML/RARA fusion gene is specific to acute promyelocytic leukemia (APL) and responds well to targeted therapy. CBFB rearrangements and MLL gene abnormalities have varying prognostic implications in different AML subtypes. By analyzing these genetic abnormalities, the Leukemia Panel helps stratify AML patients into risk groups, enabling personalized treatment plans and improved patient outcomes.

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Leukemia Panel (AML) by FISH, Heparin Bone Marrow Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Leukemia Panel (AML) by FISH, Heparin Bone Marrow with a clear pricing structure.

The Leukemia Panel (AML) by FISH, Heparin Bone Marrow Price in Mumbai is ₹ 15,900 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

This test examines specific genetic abnormalities including ETO/AML1, PML/RARA, CBFB, and MLL associated with Acute Myeloid Leukaemia.

• To diagnose Acute Myeloid Leukaemia (AML) and monitor the response to treatment • To assess the risk of relapse, determine the effectiveness of therapy, and provide valuable information for treatment

This test may be recommended if you have • symptoms suggestive of AML, such as fatigue, frequent infections, easy bruising or bleeding, or unexplained weight loss, • abnormal blood cell counts or morphology on routine blood tests, • a previous diagnosis of AML, or • treatment for AML to assess response and guide further therapy.

Abnormal results indicate the presence of these markers, suggesting a diagnosis of AML.

To conduct this test, a sample of bone marrow is collected using a Na-heparin vacutainer. The sample is processed and tested using the FISH method to detect specific genetic markers associated with AML.

• Inform your doctor about any medications you are taking as certain drugs may interfere with the test results. Also, tell them if you have any specific requirements. • Follow any instructions provided by your healthcare provider regarding fasting or medication.

• Complete Blood Count (CBC): This test provides information on the number and types of blood cells present in your sample. • Bone Marrow Aspiration and Biopsy: This procedure helps to assess the morphology and cellular composition of your bone marrow. • Flow Cytometry: This test uses specific antibodies to identify and characterise different types of cells in your blood or bone marrow.

AML FISH Panel or the Acute Myeloid Leukaemia Fluorescence In Situ Hybridization Panel

Acute Myeloid Leukaemia is a type of cancer that affects the bone marrow and blood. It is characterised by the rapid growth of abnormal myeloid cells, which are responsible for producing red blood cells, white blood cells, and platelets. AML can cause symptoms such as fatigue, frequent infections, easy bruising or bleeding, and unexplained weight loss.

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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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