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JAK-2 Mutation (CMPD) (V617F) By Real Time PCR - Bone Marrow
Also known as: JAK2 V617F Mutation Detection by RT-PCR, EDTA Bone Marrow
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
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Overview
The JAK2 Mutation (CMPD) (V617F) test, performed on bone marrow samples using real-time PCR, has clinical utility in the diagnosis of Chronic Myeloproliferative Disorders (CMPD). It specifically detects the most common mutation, V617F, in the JAK2 gene. This mutation is associated with conditions such as Polycythemia Vera, Myelofibrosis, and Essential Thrombocythemia, which are classified as CMPDs. By identifying the presence of the JAK2 V617F mutation, this test aids in confirming the diagnosis of these disorders. The JAK2 V617F mutation is considered a key molecular marker in CMPDs, providing valuable information for appropriate treatment planning and management of affected individuals.
JAK2 V617F Mutation Detection by RT-PCR, EDTA Bone Marrow Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the JAK2 V617F Mutation Detection by RT-PCR, EDTA Bone Marrow with a clear pricing structure.
The JAK2 V617F Mutation Detection by RT-PCR, EDTA Bone Marrow Price in Mumbai is ₹ 6,890 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
The JAK-2 Mutation (CMPD) Test detects the most common mutation, V617F, in the JAK2 gene.
• To diagnose Polycythemia vera, Myelofibrosis, and Essential thrombocythemia • To evaluate the effectiveness of treatment for these conditions • To monitor disease progression
• The JAK-2 Mutation (CMPD) Test is recommended if you have symptoms suggestive of Polycythemia vera, Myelofibrosis, or Essential thrombocythemia such as unexplained fatigue, dizziness, or excessive bleeding or clotting. • It is also advised for individuals with a family history or genetic risk factors for these conditions.
Abnormal results may indicate the presence of Polycythemia vera, Myelofibrosis, Essential thrombocythemia, or other related conditions.
During the test, a small amount of bone marrow is collected using a needle. The sample is sent to the laboratory for analysis using Real-Time PCR method.
• Your doctor may provide specific instructions regarding fasting or discontinuing certain medications before the test. • Inform your doctor if you have any specific requirements.
• Complete Blood Count (CBC): Evaluates various components of blood and helps diagnose blood disorders • Bone Marrow Biopsy: Assists in examining the bone marrow for abnormalities related to blood cell production • Genetic Testing: Determines other genetic mutations associated with certain myeloid disorders
JAK2 V617F Mutation Test
Polycythemia vera is a rare blood disorder characterised by the overproduction of red blood cells, white blood cells, and platelets in the bone marrow. It is often associated with the JAK-2 gene mutation.
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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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