CD99 Mic2 IHC

This test measures the presence of the CD99 Mic2 protein marker in tissue samples.

The CD99 Mic2 IHC test is done to:

• Diagnose Ewing sarcoma and PNET

• Differentiate Ewing sarcoma and PNET from other types of cancer

• Determine the stage of Ewing sarcoma and PNET

• Monitor the progress of treatment for Ewing sarcoma and PNET

• Detect recurrence of Ewing sarcoma and PNET

• Present symptoms suggestive of small round cell tumours, such as pain, swelling, or a lump
• Have undergone imaging tests that indicate the presence of a tumour
• Have a family history or genetic risk factors for small round cell tumours
• Need confirmation or further characterization of a tumour already diagnosed through other means

If the CD99 Mic2 IHC test is positive, it means that CD99 protein was found on the surface of cells. This is a strong indication that Ewing sarcoma or PNET is present. It is essential to discuss your test results with your doctor, who will consider your medical history, symptoms, and other diagnostic tests.

• You will provide a tissue sample obtained from a previous biopsy or surgery.
• The sample will be sent to the laboratory for analysis using Immunohistochemistry (IHC) staining technique.
• The laboratory experts will examine the sample under a microscope and evaluate the presence and intensity of CD99 Mic2 staining.

• Ensure that you have the original histopathology report and all relevant clinical and radiological details ready.
• Provide any necessary paperwork or consent forms required by your healthcare provider.
• Speak to your healthcare provider for any specific medication or dietary requirements.

• Fluorescence In Situ Hybridization (FISH) analysis: To detect specific genetic abnormalities associated with small round cell tumours
• Molecular testing: To identify specific genetic mutations or rearrangements that can help determine treatment options

• CD99 Mic2 Immunohistochemistry (IHC) staining
• CD99 immunostaining
• CD99 antibody staining
• CD99 marker test
• CD99 immunohistochemistry

Ewing's sarcoma and primitive neuroectodermal tumors (PNETs) are both rare types of cancer that can occur in children and young adults. They are both considered small round cell tumors, meaning that the cancer cells look similar under a microscope. Ewing's sarcoma is more common than PNET and is usually found in the bones of the pelvis, legs, or spine. It can also sometimes occur in soft tissues, such as the muscles or nerves. PNETs can occur in any part of the body, but they are most commonly found in the bones, soft tissues, and brain.