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Bcl-2 Oncoprotein IHC
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Overview
Bcl-2 Oncoprotein is a substance produced in the body that plays a role in regulating cell death and promoting cell survival. Bcl-2 oncoprotein IHC test is a useful tool in differentiating follicular hyperplasia from follicular lymphoma. Follicular hyperplasia is a non-cancerous enlargement of the lymph nodes, while follicular lymphoma is a slow-growing type of non-Hodgkin lymphoma. In follicular lymphoma, Bcl-2 is overexpressed, which means that there is too much of it in the cells. This overexpression of Bcl-2 helps the lymphoma cells to survive and grow.
Bcl-2 Oncoprotein IHC Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Bcl-2 Oncoprotein IHC with a clear pricing structure.
The Bcl-2 Oncoprotein IHC Price in Mumbai is ₹ 2,545 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
Bcl-2 oncoprotein IHC test detects the presence of Bcl-2 in tissue samples.
- To differentiate between follicular hyperplasia and follicular lymphoma
- To aid in the diagnosis and classification of lymphomas
- To determine treatment strategies for patients with lymphoma
- To monitor response to therapy and disease progression
Doctors may recommend Bcl-2 Oncoprotein testing for individuals who:
- Have enlarged lymph nodes or other symptoms suggestive of lymphoma
- Require further evaluation of an abnormal lymph node biopsy result
- Need to assess response to lymphoma treatment
- Want to monitor disease recurrence or progression
Elevated levels may indicate the presence of follicular lymphoma or other conditions associated with abnormal cell growth. However, abnormal results do not necessarily mean cancer or a serious condition; consult your doctor for further evaluation.
- Your healthcare provider will collect a tissue sample, usually from a lymph node biopsy.
- The tissue sample will be processed and stained using specific antibodies.
- A pathologist will analyse the stained sample under a microscope to determine the presence and level of Bcl-2 Oncoprotein.
- Provide the original histopathology report and relevant clinical and radiological details.
- Ensure the tissue sample is in a paraffin block format.
- Speak to your healthcare provider for specific instructions and requirements.
- Complete blood count (CBC): To assess overall blood cell counts
- Immunophenotyping: To analyse the presence of specific proteins on the surface of cells
- Fluorescence In Situ Hybridization (FISH): To detect specific chromosomal abnormalities associated with lymphomas
- IHC single marker with reporting Bcl-2 Oncoprotein
- B-cell lymphoma 2 protein or Bcl-2
Follicular lymphoma is a type of non-Hodgkin lymphoma characterised by abnormal growth of B cells in the lymph nodes. It is usually slow-growing and can cause enlarged lymph nodes, fatigue, night sweats, and weight loss. Early detection aids in effective management and treatment.
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Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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