HLAB27 Test
55+ booked in last 3 daysHLAB27 Test Overview
Human leukocyte antigen HLA-B27 is a MHC (major histocompatibility complex) class I surface antigen encoded by the B locus on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells. HLA-B27 is strongly associated with ankylosing spondylitis and other associated inflammatory diseases, such as psoriatic arthritis, inflammatory bowel disease, and reactive arthritis. HLA B27 is considered to be an important criteria for classification of Axial spondyloarthropathies & helps in establishing early diagnosis of ankylosing spondyloarthropathies before the development of irreversible deformities.
HLA-B27 is present in approximately 89% of patients with ankylosing spondylitis, 79% of patients with Reiter syndrome, and 42% of patients with juvenile rheumatoid arthritis. However, it is not diagnostic for these disorders. Approximately 8% of the normal population carries the HLA-B27 antigen.
Summary Price Of HLAB27 Test
We are a trusted lab, offering HLAB27 Test with a transparent pricing structure.
The cost of HLAB27 Test in India varies as per the city in India.
The average price of HLAB27 Test ranges from ₹1900 to ₹2875.
The price for the test in the following cities is:
- Chennai: ₹2,200
- Delhi: ₹2,100
- Mumbai: ₹2,270
- Pune: ₹2,875
Contact Metropolis to book an appointment online.
Frequently Asked Questions
The doctor may order the test for you if you have symptoms like pain, inflammation associated with stiffness of spine, neck, chest. HLAB27 test helps determine whether you have human leukocyte antigen B27 (HLA-B27) on the surface of your cells and in turn it helps assess the likelihood that you may be suffering from an autoimmune disorder. Those with the HLA-B27 variant are at a higher risk than the general population of developing the disorder. People who are HLA-B27 positive are also more likely to experience early onset Ankylosing spondylitis than HLA-B27 negative individuals.
HLAB27 test measures HLA-B27, which is a specific protein that is found on cell surfaces
HLAB27 test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.
A negative test means that there is no HLA-B27 in your blood. It is important to note that a negative HLAB27 test does not mean that you may not have an autoimmune disorder. Your doctor will make a final diagnosis basis the symptoms that you have, and test results and he may order more tests if needed. A positive test results indicates presence of HLA-B27 in your blood. If you have symptoms or signs of spondyloarthritis, a positive HLA-B27 test may help confirm the diagnosis. However, HLA-B27 is found in some normal people and does not always mean you have a disease.
Ratings & Reviews (0)
Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.