TTG IgA Test - Antibody

TTG IgA Test Overview

Celiac disease is an autoimmune disorder characterized by an inappropriate immune response to gluten, a protein found in wheat, and related dietary proteins in rye and barley.

The TTG IgA test, also known as the anti-TTG test, is a blood test used to diagnose and monitor celiac disease, an autoimmune disorder triggered by the ingestion of gluten, a protein found in wheat, rye, and barley. This test detects the presence of TTG antibodies, specifically of the IgA class, which are produced by the immune system in response to gluten. The TTG IgA test is considered the most sensitive and specific blood test for celiac disease, particularly for individuals over the age of 2 years.

Celiac disease is a chronic condition that damages the small intestine, leading to malabsorption of nutrients. When individuals with celiac disease consume gluten, their immune system responds by producing antibodies that attack the small intestine, causing inflammation and damage to the intestinal lining. The TTG IgA test helps identify this immune response and aids in the diagnosis of celiac disease, allowing for appropriate management through a gluten-free diet.