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TTG IgA Test - Antibody
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
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TTG IgA Test - Antibody Details in Brief
| Also Known As | Tissue Transglutaminase IgA Antibody Test, tTG-IgA, Coeliac Disease Antibody Test |
|---|---|
| Purpose | To help diagnose coeliac disease and gluten sensitivity, and to monitor response to a gluten-free diet |
| Preparation | No specific preparation required |
| Fasting | Fasting not required |
| Reporting Time | After 8 hours |
| Cost | 1,650 |
What Is a TTG IgA Test?
A TTG IgA Test is a blood test that measures the level of Tissue Transglutaminase (tTG) IgA antibodies in your blood to help diagnose coeliac disease and gluten sensitivity. This condition occurs when your immune system reacts abnormally to gluten, a protein found in foods like wheat, barley and rye, causing inflammation and damage to the small intestine.
Doctors recommend this test to detect coeliac disease, assess gluten intolerance, or monitor your response to a gluten-free diet. It is often performed along with a total IgA test or tTG IgG test for comprehensive evaluation. The test requires a small blood sample drawn from a vein in your arm, and fasting is not necessary.
What Does a TTG IgA Test Measure?
The TTG IgA Test helps identify immune system reactions related to gluten exposure. It provides useful information for:
- Diagnosing Coeliac Disease: Detects antibodies that indicate intestinal inflammation caused by gluten.
- Monitoring Gluten-Free Diet Compliance: Helps check if your antibody levels are normalising after dietary changes.
- Assessing Gluten Sensitivity: Distinguishes between autoimmune coeliac disease and non-coeliac gluten intolerance.
- Evaluating Malabsorption Syndromes: Detects nutrient absorption problems associated with intestinal damage.
- Investigating Autoimmune Conditions: Supports the diagnosis of other IgA-mediated autoimmune responses.
TTG IgA Test: Who Needs It and Why It’s Done
What Symptoms May Call for a TTG IgA Test?
Your doctor may recommend this test if you experience symptoms such as:
- Persistent diarrhoea or constipation
- Abdominal bloating, gas, or cramps after eating gluten-containing foods
- Unexplained fatigue or weight loss
- Iron deficiency anaemia that does not improve with supplements
- Skin rash (dermatitis herpetiformis)
- Mouth ulcers, headaches, or bone pain
- Malnutrition or poor growth in children
Who Should Get a TTG IgA Test?
- People showing symptoms suggestive of coeliac disease
- Individuals with a family history of coeliac disease or autoimmune disorders
- Patients with unexplained anaemia or vitamin deficiencies
- Children with poor growth, irritability, or persistent digestive issues
- Those on a gluten-free diet to monitor treatment effectiveness
Why Is a TTG IgA Test Done?
A TTG IgA Test helps confirm or rule out coeliac disease, guiding appropriate dietary and medical management. It also helps assess the effectiveness of a gluten-free diet in reducing antibody levels and improving symptoms.
Importance of a TTG IgA Test
The TTG IgA Test is the most accurate and widely used screening tool for coeliac disease. Detecting elevated levels of TTG IgA antibodies enables early diagnosis, preventing complications such as malnutrition, osteoporosis, infertility, and intestinal cancer. Regular monitoring helps ensure effective management and healing of the intestinal lining once a gluten-free diet is started.
TTG IgA Test Booking & Reports – Metropolis Healthcare
How to Book the TTG IgA Test and Get Your Reports?
- Simple Online Booking
Book your TTG IgA Test through the Metropolis Healthcare App or website. Choose a suitable time slot and enter your address for a home blood sample collection. You can also visit your nearest Metropolis Lab for in-person testing. - Safe Home Sample Collection
Our trained phlebotomists collect your sample at your preferred time, following strict hygiene and safety standards. - Sample Tracking Updates
You can track your sample’s status at every step, from collection to report availability, via the Metropolis website. - Accurate Laboratory Testing
Your sample is analysed in our NABL & CAP accredited laboratories using Chemiluminescence Immunoassay (CLIA), ensuring precise detection of antibodies. - Quick & Easy Reports
Get your reports quickly through email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is Home Sample Collection for TTG IgA Test Available Near You?
Yes. Metropolis Healthcare offers home sample collection for the TTG IgA Test. Our trained phlebotomists visit your home at a time convenient for you, ensuring comfort, safety and accurate sample handling without needing a clinic visit.
In How Much Time Will I Get TTG IgA Test Report?
Reports are usually available within 8 hours once your sample reaches the lab.
Note: Reporting time and cost may vary based on your location.
Where Can I See or Get TTG IgA Test Results?
Test results from Metropolis Healthcare can be accessed conveniently. You can log in to the Metropolis website or use the Metropolis Healthcare App to view and download your reports. Reports are also sent via email or WhatsApp, and you can collect a physical copy from your nearest lab.
Interpreting TTG IgA Test Results
What Your TTG IgA Test Results May Indicate
| Parameter | Normal Range | High Values May Indicate | Low/Negative Values May Indicate |
|---|---|---|---|
| TTG (Tissue Transglutaminase) IgA Antibody | Negative: < 8 AU/mL | Coeliac disease or gluten-sensitive enteropathy | Absence of coeliac disease; may also occur in IgA deficiency |
Understanding Abnormal TTG IgA Test Results by Parameter
| Result Type | Possible Interpretation |
|---|---|
| Positive TTG IgA (> 8 AU/mL) | Suggests coeliac disease or gluten-sensitive enteropathy |
| Borderline or Equivocal Values | May require repeat testing or additional tests like tTG IgG or Endomysial Antibody |
| Negative TTG IgA (< 8 AU/mL) | Usually indicates no active coeliac disease but may be false-negative in IgA deficiency |
How Should You Prepare for a TTG IgA Test?
The TTG IgA Test needs minimal preparation. Follow these simple steps:
- No fasting required: You can eat and drink normally before the test.
- Continue a gluten-containing diet: Do not start a gluten-free diet before testing, as it can affect accuracy.
- Medication review: Inform your doctor about any immunosuppressive or corticosteroid medicines you are taking.
- Stay hydrated: Drink normal amounts of water before your test.
- Relax and rest: Try to stay calm; stress does not affect antibody levels directly but can make you uncomfortable during testing.
How Is a TTG IgA Test Done? (Step-by-Step Procedure)
The TTG IgA Test follows a standard blood collection process:
- Preparation: No fasting or special steps needed.
- Cleaning: The skin on your arm is cleaned with an antiseptic solution.
- Blood Draw: A sterile needle is inserted into a vein to collect blood.
- Sample Collection: Around 2 ml of blood is drawn into a gel vacutainer tube.
- Completion: A bandage is applied once the needle is removed.
- Processing: The sample is analysed using advanced CLIA technology in the lab.
Conditions That May Affect TTG IgA Test Accuracy
Several factors can influence your TTG IgA test results:
- Starting a gluten-free diet before testing can reduce antibody levels and cause false-negative results.
- IgA deficiency may result in an inaccurate or falsely negative test.
- Immunosuppressant or steroid therapy can reduce antibody production.
- Recent infections or severe illnesses may temporarily alter immune activity.
Diseases That a TTG IgA Test Can Help Detect
- Coeliac disease
- Gluten-sensitive enteropathy
- Autoimmune enteropathy
- Dermatitis herpetiformis
- Malabsorption syndromes
- Gluten intolerance
Home Collection for TTG IgA Test
Metropolis Healthcare offers a convenient home sample collection service for the TTG IgA test. A trained phlebotomist will visit your doorstep to collect the blood sample, ensuring comfort and safety while maintaining high standards of sample handling and testing accuracy. This service allows individuals to undergo the test without the need to visit a diagnostic center, making healthcare more accessible. With timely and reliable results, Metropolis Healthcare is committed to providing quality diagnostic solutions conveniently at home, empowering individuals to take proactive steps in managing their health.
TTG IgA Test Price in Different Cities
The cost of a TTG IgA Test may vary depending on your location. Here's a table showing the approximate price range for the TTG IgA Test at Metropolis Healthcare in major Indian cities:
|
City |
Approximate Cost (INR) |
|
₹ 1000 to ₹ 2000 |
|
|
₹ 1000 to ₹ 2000 |
|
|
₹ 1000 to ₹ 2000 |
|
|
₹ 1000 to ₹ 2000 |
TTG IgA Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive TTG IgA Test prices across major cities in India.
References
- Ludvigsson, J.F., Bai, J.C., Biagi, F., et al. (2014). Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology. Gut, 63(8), 1210–1228. PMID: 24917550
- Rubio-Tapia, A., Hill, I.D., Kelly, C.P., Calderwood, A.H., Murray, J.A. (2013). ACG clinical guidelines: diagnosis and management of celiac disease. American Journal of Gastroenterology, 108(5), 656–676. PMID: 23609613
- Husby, S., Koletzko, S., Korponay-Szabó, I.R., et al. (2012). European Society for Paediatric Gastroenterology guidelines for coeliac disease. Journal of Pediatric Gastroenterology and Nutrition, 54(1), 136–160. PMID: 22197856
- Hill, I.D., Fasano, A., Guandalini, S., Hoffenberg, E., Levy, J., Reilly, N., et al. (2016). NASPGHAN clinical report on the diagnosis and treatment of celiac disease. Journal of Pediatric Gastroenterology and Nutrition, 63(1), 158–176. PMID: 27214376
- Rostom, A., Murray, J.A., Kagnoff, M.F. (2006). American Gastroenterological Association technical review on celiac sprue. Gastroenterology, 131(6), 1981–2002. PMID: 17087937
TTG IgA Test - Antibody Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the TTG IgA Test - Antibody with a clear pricing structure.
The TTG IgA Test - Antibody Price in Mumbai is ₹ 1,650 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
It detects antibodies produced by your immune system against tissue transglutaminase, helping diagnose coeliac disease and gluten sensitivity.
No, fasting is not required for this test.
Yes, starting a gluten-free diet before testing can lower antibody levels and cause false-negative results.
A small blood sample is collected from a vein in your arm and analysed in the lab using the CLIA method.
Occasionally, autoimmune diseases like type 1 diabetes or thyroiditis may show mildly raised antibody levels.
Reports are generally available within 8 hours after your sample reaches the lab.
A normal or negative result is less than 8 AU/mL. Values above this suggest coeliac disease or gluten sensitivity.
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