Maternal Screen (QUAD test) - 1st Trimester with Preeclampsia

The First-trimester test, also known as the Serum Quad Test, is a prenatal screening test that is usually performed during the first trimester of pregnancy (between weeks 11 to 13.6). This test measures the levels of four substances in the mother's blood: free beta human chorionic gonadotropin (free beta hCG), pregnancy-associated plasma protein A (PAPP-A), alpha-fetoprotein (AFP), and inhibin A.

Free beta hCG is a hormone produced by the placenta that can be detected in the mother's blood. Abnormal levels of free beta hCG can be associated with chromosomal abnormalities such as Down syndrome, as well as other complications such as preeclampsia. PAPP-A is a protein produced by the placenta that is essential for fetal growth and development. Low levels of PAPP-A can be associated with an increased risk of chromosomal abnormalities, fetal growth restriction, and preeclampsia. AFP is a protein produced by the fetus that can be detected in the mother's blood. Abnormal levels of AFP can be associated with neural tube defects such as spina bifida. Inhibin A is a protein produced by the placenta that helps regulate hormone levels during pregnancy. Abnormal levels of inhibin A can be associated with an increased risk of chromosomal abnormalities and preeclampsia.