JAK2 V617 Mutation, with Reflex to Jak2 Ex- 12, CALR Ex-9 Mutation and MPL W515, S505 Mutation,Bone Marrow Test in Darbhanga
₹13500
₹13500
This reflex test sequentially evaluates for the common major gene variants associated with non-BCR-ABL1-positive myeloproliferative neoplasms until a variant is identified.
This test will assess for the JAK2V617F (exon 14) mutation first and will reflex to CALR mutation analysis, JAK2 exon mutation analysis and MPL mutation analysis when the JAK2V617F mutation is negative.
Your doctor may prescribe this test in conjunction with bone marrow histology and cytogenetic analysis to assist in the diagnosis of myeloproliferative neoplasms (MPN).
This reflex test sequentially evaluates for the common major gene variants associated with non-BCR-ABL1-positive myeloproliferative neoplasms until a variant is identified. The testing sequence is based on the reported frequency of gene variants in this disease group. Initial testing evaluates for the presence of the JAK2 V617F variant. If this result is negative or very low positive (0.06%-0.6%), testing proceeds with assessment for CALR gene variants. If the CALR result is also negative, then testing proceeds to evaluate for variants in exon 10 of the MPL gene. If either JAK2 V617F (>0.6%) or CALR variants are detected in the process, the testing algorithm ends; therefore, the complete reflex is followed only in the event of sequential negative variant. An integrated report is issued with the summary of test results.
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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
Frequently Asked Questions
Yes our laboratory is accredited by the NABL (National Accreditation Board of Testing and Calibration of Laboratories) India & College of American Pathologists (CAP). This accreditation process is carried out every 2 years for NABL & annually for CAP with periodic internal audits carried out twice in a year. All our aforementioned tests are accredited by NABL & CAP.
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Additional Home Visit and Safety charges will be applicable for all test and Health packages.
We collect samples from home between 7 AM to 11 PM (in Mumbai) and 7 AM to 9 PM in other cities. we offer Blood collection service on Sunday’s as well.
Doctor’s prescription is not required if you avail any wellness package. For any illness test, prescription might be required.
Test samples are processed at our regional laboratories in various cities – Mumbai, Pune, Chennai, Bangalore, Delhi and more. You can check out more information here – Our Labs
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