D3 Hydroxybutarate (Ketone)

The D-3-Hydroxybutyrate Serum Test measures the concentration of D-3-hydroxybutyrate in the blood serum. Elevated levels of this ketone body can indicate ketosis, a state where the body relies on fat breakdown for energy.

The test is performed for the following reasons:

• To assess patients experiencing hypoglycemia (low blood sugar) to determine if ketone production is contributing to their symptoms
• To diagnose or monitor metabolic acidosis, a condition characterized by an excess of acid in the body
• To confirm the presence of ketosis in individuals suspected of alcohol ingestion or certain metabolic disorders

The D-3-Hydroxybutyrate Serum Test is recommended in the following situations:

• When a patient exhibits symptoms of hypoglycemia, including confusion, shakiness, and sweating
• For individuals with suspected metabolic acidosis, a condition often accompanied by symptoms like rapid breathing, confusion, or fatigue
• In cases where alcohol ingestion is suspected and ketosis needs to be confirmed
• Patients who require monitoring during specific medical treatments or dietary interventions that can induce ketosis

The results of the D-3-Hydroxybutyrate Serum Test reflect the concentration of D-3-hydroxybutyrate in the blood serum. Elevated levels suggest the presence of ketosis, which may be due to factors like fasting, uncontrolled diabetes, alcohol ingestion, or certain metabolic conditions. Normal levels indicate the absence of ketosis.

The test involves a blood draw, where a healthcare professional collects a blood sample from a vein, typically in the arm. The procedure is relatively quick and minimally invasive.

Before the test, patients may not need extensive preparations. However, it is essential to follow any specific instructions provided by the healthcare provider, such as fasting for a certain period if required.

Additional tests that may be ordered alongside the D-3-Hydroxybutyrate Serum Test include:

• Blood glucose measurement: To assess blood sugar levels, particularly if hypoglycemia is suspected
• Blood gas analysis: To evaluate acid-base balance in cases of metabolic acidosis
• Comprehensive metabolic panel (CMP): To provide a broader assessment of electrolyte and metabolic status
• Liver function tests: If alcohol ingestion is suspected, these tests may help assess liver health and function

• Serum D-3-Hydroxybutyrate Test
• Ketone Serum Test