Cortisol Serum Test
Also known as: Cortisol Test - Serum
Cortisol Test - Serum Details in Brief
| Also Known As | Cortisol - 8am, Serum Cortisol, Plasma Cortisol |
|---|---|
| Purpose | Evaluates adrenal gland function, helps diagnose Cushing's syndrome and adrenal insufficiency |
| Preparation | High biotin dose (>5 mg/day) should be avoided at least 8 hours before blood collection |
| Fasting | Not required |
| Reporting Time | After 6 hours |
| Cost | 650 |
What is a Cortisol Test?
A cortisol test measures the level of cortisol, your body's primary stress hormone, in your blood. This hormone is produced by your adrenal glands, which sit on top of your kidneys. The test determines how well your adrenal glands are working and helps doctors diagnose conditions like Cushing's syndrome (too much cortisol) or Addison's disease (too little cortisol).
What does the Cortisol Test measure?
The cortisol test serves several important medical purposes:
- Evaluates how well your adrenal glands are functioning
- Helps diagnose Cushing's syndrome when cortisol levels are too high
- Detects adrenal insufficiency when cortisol production is too low
- Assesses your body's stress response and daily hormone rhythm
- Monitors the effectiveness of glucocorticoid therapy treatment
- Supports detection of Addison's disease
- Investigates unexplained fatigue and unexplained weight changes
- Aids in assessing pituitary gland function
Cortisol Test: Who Needs It and Why It's Done
What Symptoms May Call for a Cortisol Test?
Your doctor may recommend a cortisol test if you experience symptoms that suggest hormone imbalances:
- Unexplained weight gain, especially around your face and upper back
- High blood pressure that's difficult to control
- Muscle weakness and fatigue
- Mood changes like depression or irritability
- Skin that bruises easily or develops purple stretch marks
- Constant tiredness and unexplained weight loss
- Low blood pressure causing dizziness
- Darkening of your skin, particularly on scars and skin folds
- Craving for salty foods
- Nausea, vomiting, or stomach pain
Who should get a Cortisol Test?
Several groups of people may benefit from cortisol testing:
- Patients experiencing symptoms of high or low cortisol levels
- Individuals with suspected adrenal or pituitary gland disorders
- People taking long-term steroid medications like prednisone
- Patients with known tumours affecting hormone-producing glands
- Those undergoing treatment monitoring for diagnosed hormone conditions
- Individuals with unexplained metabolic changes
Why is a Cortisol Test done?
The cortisol test provides doctors with essential information to diagnose serious hormone-related health conditions and guide appropriate treatment decisions for your overall health.
Importance of a Cortisol Test
The cortisol test plays a crucial role in maintaining your health because cortisol affects many vital body functions, including metabolism, immune response, and blood pressure regulation. This test is clinically significant because it helps doctors identify hormone imbalances that could lead to serious health risks or complications if left untreated.
Early detection through cortisol testing enables timely treatment, which can prevent long-term health problems and improve your quality of life. The test also helps doctors monitor treatment effectiveness and adjust medications as needed.
Cortisol Test Booking & Reports – Metropolis Healthcare India
How to Book a Cortisol Test?
- Simple Online Booking
Booking can be done through the Metropolis Healthcare app or website. Select the Cortisol Test, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab. - Safe Home Sample Collection
Our trained phlebotomists ensure timely collection of your sample while strictly following all safety and hygiene protocols. - Sample Tracking Updates
Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website. - Accurate Laboratory Testing
Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results. - Quick & Easy Reports
Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is home sample collection for Cortisol Test available near you?
Yes, home blood sample collection is available for the cortisol test. Our trained phlebotomists visit your home at your preferred time, following strict safety protocols to collect your blood sample. This service eliminates travel time and waiting at a pathology lab, making it easier for you to get tested in familiar surroundings. With Metropolis Healthcare's commitment to accessible testing, you can trust that your sample will be handled professionally and processed at our accredited laboratories.
How Long Does It Take to Get a Cortisol Test Report?
Reports are usually available 6 hours after the sample reaches the lab.
Where can I see or get Cortisol Test results?
Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare app to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.
Interpreting Cortisol Test Results
What Your Cortisol Test Results May Indicate
The following table shows the normal range and what abnormal results might suggest:
|
Parameter |
Reference Range |
High Values May Indicate |
Low Values May Indicate |
|
Cortisol - 8am (Serum) |
5-23 μg/dL |
Cushing syndrome, adrenal tumours, pituitary adenoma, stress, depression, hyperthyroidism |
Addison's disease, primary adrenal insufficiency, secondary adrenal insufficiency, pituitary insufficiency, congenital adrenal hyperplasia |
Conditions that May Affect Cortisol Test Accuracy
Several factors can influence your cortisol test results and should be discussed with your doctor:
- High biotin supplements (over 5mg daily) taken within 8 hours before testing can interfere with results
- Steroid medications including pills, injections, or creams can significantly alter cortisol levels
- Physical or emotional stress on the day of testing may cause temporary elevation
- Intense exercise immediately before the test can raise cortisol levels
- Certain medications like oestrogen and some anticonvulsants may affect readings
- Dehydration or illness can temporarily increase cortisol production
- Changes in protein levels in your blood can affect total cortisol measurements
How is a Cortisol Test Done?
The cortisol test follows a simple blood collection procedure:
- A healthcare professional cleans the area on your arm, usually inside your elbow
- They tie a band around your upper arm to make the vein more visible
- A small needle is inserted into the vein to collect blood
- Your blood sample is collected into a special tube
- The needle is removed and pressure is applied to stop any bleeding
- The sample is labelled and sent to the laboratory for analysis
- The entire process takes just a few minutes
How Should You Prepare for a Cortisol Test?
Cortisol test preparation requires following a few simple guidelines:
- No fasting required: You can eat and drink normally before the test
- Timing matters: The test is typically done in the morning around 8 AM when cortisol levels are highest
- Medication review: Inform your doctor about all medications, especially steroids or biotin supplements
- Avoid high biotin: Stop taking biotin supplements over 5mg daily at least 8 hours before testing
- Stay calm: Try to remain relaxed as stress can affect cortisol levels
- Rest beforehand: Avoid intense physical exercise before your appointment
Diseases that a Cortisol Test Can Help Detect
The cortisol test can help identify several important medical conditions:
- Cushing's syndrome caused by excess cortisol production
- Addison's disease resulting from insufficient cortisol
- Primary adrenal insufficiency affecting hormone production
- Secondary adrenal insufficiency due to pituitary problems
- Congenital adrenal hyperplasia, a genetic condition
- Adrenal tumours that affect hormone levels
- Pituitary adenomas or carcinomas
- Stress-related hormone disorders
Cortisol Test/Packages that You Can Book With Metropolis Healthcare
Here are related tests that can provide comprehensive hormone assessment along with the cortisol test:
|
Test/Package Name |
Purpose/Highlights |
|
Measures cortisol levels in urine over 24 hours for comprehensive assessment |
|
|
Specialised test to diagnose Cushing's syndrome by suppressing cortisol production |
|
|
Measures cortisol at any time of day for general screening |
|
|
Evaluates adrenal gland response to stimulation hormone |
Cortisol Test Prices in Different Cities
The cost of a cortisol test may vary depending on your location. Here's a table showing the approximate prices in different cities.
|
City |
Price |
|
₹640 To ₹1050 |
|
|
₹640 To ₹1050 |
|
|
₹640 To ₹1050 |
|
|
₹640 To ₹1050 |
|
|
₹640 To ₹1050 |
|
|
₹640 To ₹1050 |
Cortisol Test - Serum Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Cortisol Test - Serum with a clear pricing structure.
The Cortisol Test - Serum Price in Trivandrum is ₹ 650 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
The best time for a cortisol test is early morning, around 8 AM, when your cortisol levels naturally peak. This timing provides the most accurate assessment of your adrenal gland function.
No, overnight fasting is not required for the cortisol test. You can eat and drink normally before your appointment, though you should follow any specific instructions from your doctor.
Yes, dehydration can temporarily increase cortisol levels as it creates physical stress on your body. It's important to stay well-hydrated before your test for accurate results that reflect your baseline cortisol status.
Inform your doctor about all medications, especially steroids, oestrogen, and anticonvulsants. Avoid high-dose biotin supplements for at least 8 hours before testing. No specific dietary restrictions are needed for this test.
The procedure involves cleaning your arm, tying a band to make veins visible, inserting a small needle to collect blood, and applying pressure afterward. The entire process takes just a few minutes.
The risks are minimal and similar to any blood test. You may experience slight pain, minor bruising, or dizziness. Serious complications like infection are extremely rare with proper sterile technique.
Normal cortisol levels for an 8 AM blood test typically range from 5-23 μg/dL. Speak to your doctor for accurate result interpretations.
The cortisol test may also be called Serum Cortisol, Plasma Cortisol, Cortisol Blood Test, or Morning Cortisol Test, depending on the specific type and timing of the sample collection.
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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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