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BRCA1/2 TARGETED MUTATION ANALYSIS (FAMILY MEMBERS) in Urapakkam

Also known as: NextGen : BRCA Targeted Mutation Detection, EDTA Blood

50+ booked in last 3 days

Test Overview

Breast and Ovarian cancers are the commonest forms of cancer in women. 5-10% of breast cancers and 15-20% of ovarian cancers are hereditary and are due to a mutation in the cancer gene. Germline mutations in BRCA1 and BRCA2 genes are inherited in an autosomal dominant manner and are associated with an increased risk of breast and ovarian cancer, Fallopian tube, Peritoneal, prostate cancer and melanoma. BRCA gene test detects specific germline mutation in BRCA 1 and BRCA2 that was detected in the index case in the family by PCR- Sanger sequencing.

The BRCA1 and BRCA2 genes are the two that are most frequently impacted in hereditary breast and ovarian cancer. BRCA1 and BRCA2 gene mutations account for roughly 3% of breast cancers (affecting about 7,500 people annually) and 10% of ovarian cancers (affecting about 2,000 women annually).

The BRCA1 and BRCA2 genes often guard you against developing specific tumors. However, some abnormalities in the BRCA1 and BRCA2 genes make them unable to function normally, making it more probable for someone to inherit one of these mutations and develop breast, ovarian, and other cancers. The risk of developing breast or ovarian cancer is not universal among people who inherit a BRCA1 or BRCA2 mutation.

Test Overview

The most frequent types of cancer in women are breast and ovarian. Hereditary cancer is caused by a mutation in the cancer gene and accounts for 5–10% of breast cancers and 15–25% of ovarian cancers. The risk of melanoma, peritoneal, breast, ovarian, fallopian tube, and peritoneal cancer is raised by hereditary germline mutations in the BRCA1 and BRCA2 genes, which are inherited in an autosomal dominant way. With the help of PCR-Sanger sequencing, the index case in the family's BRCA1 and BRCA2 germline mutations were identified, and this test may identify those mutations.

The first step is to gather information about breast and ovarian cancer in your family history and give it to your doctor if you are worried that you might have a BRCA1, BRCA2, or any other mutation linked to breast and ovarian cancer.

Who Should Do the BRCA1/2 TARGETED MUTATION ANALYSIS (FAMILY MEMBERS)?

Patients with early-onset breast and/or ovarian cancer who come from families where these diseases have been diagnosed frequently are prime candidates for BRCA mutations. Because a specific BRCA mutation does not always result in cancer in a specific person, BRCA testing is predictive.

What Other Tests Are Ordered Along with the BRCA1/2 TARGETED MUTATION ANALYSIS (FAMILY

MEMBERS)?

A specific deleterious BRCA1 or BRCA2 gene mutation which has previously been found in a family member is the focus of certain tests. Other assays examine both genes for all known dangerous mutations.

Written by: Dr Vishal Wadhwa, M.D, D.N.B Microbiology, Medical Affairs

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NextGen : BRCA Targeted Mutation Detection, EDTA Blood Price in Chennai

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the NextGen : BRCA Targeted Mutation Detection, EDTA Blood with a clear pricing structure

The price of NextGen : BRCA Targeted Mutation Detection, EDTA Blood in Chennai is ₹ 5,300

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

How it Works?

All our phlebotomists are vaccinated

At Metropolis Healthcare, your well-being is our top priority. Rest assured, all our skilled phlebotomists are vaccinated, ensuring a safe and secure experience for you. Our team upholds the highest healthcare standards, and your health is in capable hands. Your safety is non-negotiable, and at Metropolis, we take every measure to guarantee it.

Our Phlebotomists maintain a high standard of safety precautions

Our dedicated team of phlebotomists prioritises your safety before anything else. They implement stringent safety measures to guarantee your well-being during their visit.

Strictly adhering to aseptic techniques, our phlebotomists maintain a sterile environment with thorough sanitization and the use of gloves, masks and face shields. Needles are disposed of with utmost care, following rigorous guidelines to minimise any potential risks. We leave no room for compromise when it comes to personal protective equipment (PPE), ensuring both you and our staff are well protected.

Our phlebotomists collect samples safely

The phlebotomists at Metropolis Healthcare are proficient in safe sample collection. They skillfully and gently draw blood, minimizing any discomfort you may feel. We prioritize your safety by using sterile, single-use needles and barcoded vials to completely eliminate any risk of cross-contamination. Our collection area is carefully sanitized before, during, and after your sample collection.

Samples are processed at high-tech facilities

Metropolis Healthcare takes pride in its state-of-the-art facilities, where your samples are thoroughly processed. Our labs are equipped with cutting-edge machinery with advanced technology, eliminating chances of human error. From the moment your sample arrives at our facility, it undergoes an automated process.

Your samples are stored in clean and secure facilities

We leave no room for compromise when it comes to the storage of your samples. Our storage facilities are regularly cleaned and disinfected, upholding the highest standards of healthcare safety.

Temperature-controlled environments and cooling facilities ensure that your samples remain fresh and the results produced are accurate. Our cutting-edge security measures prevent unauthorized access, guaranteeing the confidentiality of your health data.

Metropolis provides accurate digital reports

Our advanced sample processing machines not only deliver swift results to you but also generate precise digital reports. We provide conclusive diagnoses through meticulous re-checks and repeat specimen analyses, if required, at no extra cost, adding an extra layer of accuracy and dependability. This unique approach sets us apart, earning the trust of top doctors and hospitals across the country.

Your health is our priority, and we spare no effort in our commitment to providing you with the most accurate insights you can rely on.

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Why Metropolis?

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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