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Bile Acids Test - Total, Serum

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Bile Acids Test - Total, Serum Details in Brief

Also Known As Total Serum Bile Acid Test, Bile Acid Level Test, Bile Acid Function Test
Purpose Assesses liver funcation, bile acid metabolism, and detects cholestatic liver diseases including intrahepatic cholestasis of pregnancy (ICP)
Preparation Fasting recommended (8 to 10 hours)
Fasting Required
Reporting Time After 6 hours
Cost 2,340

What is a Bile Acids Test?

The Bile Acids Test is a blood test that measures the concentration of bile acids in your bloodstream to evaluate liver function and bile acid metabolism. Bile acids are natural substances produced by your liver to help digest fats. Normally, they circulate between your liver and intestines in a tightly regulated process.

If your liver is damaged or bile flow is blocked (a condition known as cholestasis), bile acids can leak into the bloodstream, leading to elevated levels.

This test is particularly important for diagnosing conditions such as intrahepatic cholestasis of pregnancy (ICP), hepatitis, cirrhosis, biliary obstruction, and other metabolic liver disorders.

What Does the Bile Acids Test Measure?

The Bile Acids Test measures total bile acid concentration in the blood, including both primary and secondary bile acids.

  • Liver Function: Determines how well the liver produces, recycles, and clears bile acids.
  • Bile Flow Assessment: Detects obstruction or reduced flow in bile ducts (cholestasis).
  • Metabolic Screening: Identifies disorders affecting bile acid synthesis or transport.
  • Pregnancy Monitoring: Detects intrahepatic cholestasis of pregnancy (ICP), a liver disorder that occurs in late pregnancy.
  • Treatment Response: Monitors liver function recovery or response to therapy in liver disease patients.

Why is a Bile Acids Test Done?

Doctors recommend a Bile Acids Test to:

  • Detect cholestasis or bile flow obstruction.
  • Diagnose intrahepatic cholestasis of pregnancy (ICP) when pregnant women experience itching, especially in the third trimester.
  • Evaluate liver disorders such as hepatitis, cirrhosis, or fatty liver disease.
  • Identify gallbladder or bile duct diseases.
  • Monitor the effects of hepatotoxic medications or liver-impacting treatments.
  • Assess newborns or infants for inherited metabolic liver disorders.

Who Should Get a Bile Acids Test?

This test is advised if you have:

  • Persistent itching (pruritus) during pregnancy.
  • Symptoms of liver disease such as fatigue, jaundice (yellowing of eyes/skin), or dark urine.
  • Known biliary or gallbladder disorders.
  • Family history of liver disease or metabolic dysfunction.
  • Unexplained elevations in liver enzymes (AST, ALT, ALP).

What are Bile Acids and Why Are They Important?

Bile acids are compounds made from cholesterol in the liver and stored in the gallbladder. They help digest fats, absorb fat-soluble vitamins (A, D, E, K), and maintain cholesterol balance.

In healthy individuals, bile acids travel from the liver to the intestine and back through a process called enterohepatic circulation. When liver function is impaired or bile flow is blocked, bile acids accumulate in the blood, causing toxic effects on cells and tissues.

Bile Acids Test Booking & Reports – Metropolis Healthcare

How to Book the Bile Acids Test and Get Your Reports

  1. Online Booking
    Book your Bile Acids Test through the Metropolis Healthcare website or app. Choose a convenient time slot and location.
  2. Home Sample Collection
    Metropolis offers safe home collection services by trained phlebotomists for added convenience.
  3. Laboratory Testing
    Samples are analysed using the Enzymatic method in NABL & CAP accredited labs for accurate measurement of bile acid levels.
  4. Quick Report Delivery
    Reports are available within 6 hours, delivered via email, WhatsApp, or accessible on the Metropolis Healthcare portal.

How Long Does It Take to Get Bile Acids Test Results?

Reports are typically available within 6 hours of sample reaching our Lab.

Note: Reporting time may vary based on your location.

Where Can I See or Collect Bile Acids Test Reports?

You can access your report through:

  1. Metropolis Healthcare website or mobile app
  2. Email or WhatsApp delivery
  3. Physical copies at your nearest Metropolis Lab

Is Home Sample Collection Available for Bile Acids Test?

Yes. Metropolis Healthcare provides doorstep sample collection across major cities. This service ensures convenience, hygiene, and comfort for patients, especially expecting mothers.

Interpreting Bile Acids Test Results

Normal and Abnormal Bile Acids Levels

Bile Acids Level (µmol/L) Interpretation
0.5 – 10 µmol/L Normal range; indicates healthy liver function and bile flow.
>10 µmol/L Suggests impaired bile flow, liver dysfunction, or cholestasis.
>40 µmol/L (in pregnancy) Indicates intrahepatic cholestasis of pregnancy (ICP), requiring immediate medical attention.

 

Understanding Abnormal Results

Condition Expected Change in Bile Acids Explanation
Cholestasis Elevated Indicates blockage or reduced bile flow within the liver or bile ducts.
Cirrhosis or Hepatitis Elevated Suggests liver cell damage or impaired bile processing.
Gallstones or Biliary Obstruction Elevated Blockage prevents bile drainage, increasing bile acids in blood.
Intrahepatic Cholestasis of Pregnancy (ICP) Markedly Elevated Bile acid buildup during pregnancy causing itching and potential fetal risk.
Metabolic Disorders Elevated Genetic defects in bile acid synthesis or transport.

 

Preparation for the Bile Acids Test

  • Fasting: Avoid eating or drinking (except water) for 8 to 10 hours before the test.
  • Medication Review: Inform your doctor about any liver-impacting medications, supplements, or hormonal treatments.
  • Hydration: Stay hydrated to make blood collection easier.
  • Avoid Alcohol: Do not consume alcohol 24 hours before the test.
  • Pregnancy Notification: Pregnant women should inform the phlebotomist and clinician before testing.

What to Expect During the Bile Acids Test

  • A small blood sample (about 2 ml) is drawn from a vein in your arm.
  • The process takes only a few minutes and involves minimal discomfort.
  • After sample collection, you can resume your normal activities immediately.

Associated Tests

Your doctor may recommend additional tests alongside the Bile Acids Test to assess complete liver function, such as:

  • Liver Function Test (LFT)
  • Bilirubin (Total and Direct)
  • Alkaline Phosphatase (ALP)
  • Gamma-Glutamyl Transferase (GGT)
  • Hepatitis Panel
  • Ultrasound of Liver and Gallbladder

Bile Acids Test Price in Different Cities

The cost of a Bile Acids Test may vary depending on your location. Here's a table showing the approximate price range for the Bile Acids Test at Metropolis Healthcare in major Indian cities:

City

Approximate Cost (INR)

Mumbai

₹ 1700 to ₹ 2400

Delhi

₹ 1700 to ₹ 2400

Bengaluru

₹ 1700 to ₹ 2400

Chennai

₹ 1700 to ₹ 2400

 

The Bile Acids Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive Bile Acids Test prices across major cities in India.

References

  1. Geenes V, Williamson C. (2009). Intrahepatic Cholestasis of Pregnancy. World Journal of Gastroenterology, 15(17), 2049–2066. PMID: 19418576
  2. Trauner M, et al. (2017). Pathogenesis and Management of Cholestasis. New England Journal of Medicine, 377(13), 1258–1271. PMID: 28953447
  3. Cui D, et al. (2018). Serum Bile Acids in the Diagnosis of Liver Diseases. Clinical Chemistry and Laboratory Medicine, 56(6), 857–866. PMID: 29565238
  4. Kit Insert – Metropolis Healthcare Bile Acids Assay.
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Bile Acids Test - Total, Serum Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Bile Acids Test - Total, Serum with a clear pricing structure.

The Bile Acids Test - Total, Serum Price in Mumbai is ₹ 2,340 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Yes, an 8 to 10-hour fast is recommended before sample collection.

High levels suggest liver dysfunction, cholestasis, or bile duct blockage.

Reports are available within 6 hours after sample collection.

Yes, it is the most sensitive test for intrahepatic cholestasis of pregnancy (ICP).

Yes, Metropolis offers home sample collection for this test.

The normal range is 0.5 – 10 µmol/L. Levels above this indicate possible liver or bile flow disorders.

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