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ALLERGY DRUG PANEL - (COMPREHENSIVE - 35 DRUG)

Also known as: Drug Panel - Comprehensive (35Drugs), Serum

51+ booked in last 3 days

Drug Panel - Comprehensive (35Drugs), Serum Details in Brief

Also Known As Allergen Sensitivity Panel, Comprehensive, Allergy Drug Panel - Comprehensive 35 Drugs, Drug Allergen Specific IgE Panel
Purpose To detect drug allergen specific IgE antibodies linked to possible allergic sensitivity to 35 medicines
Preparation Clinical history if any
Fasting Fasting not required
Reporting Time Same day
Cost 17,500

What is the Drug Panel - Comprehensive (35Drugs), Serum?

The Drug Panel - Comprehensive (35Drugs), Serum is a blood test that helps detect specific IgE antibodies against 35 commonly used medicines. IgE antibodies are immune proteins that may be involved in immediate allergic reactions.

This test is performed on a serum sample, which is obtained from blood drawn from a vein in your arm. It uses Enzyme Immunoassay (EIA) to check whether your immune system shows sensitisation to any of the drugs included in the panel.

Your doctor may advise this test if you have had symptoms such as hives, swelling, breathing difficulty, rash, wheezing, or other suspected allergic reactions after taking a medicine. The result helps support drug allergy evaluation, but it does not replace your doctor’s clinical assessment.

What Does a Drug Panel - Comprehensive (35Drugs), Serum Measure?

The Drug Panel - Comprehensive (35Drugs), Serum measures drug allergen specific IgE antibodies in your blood.

This test helps assess:

  • Antibiotic sensitivity: Checks IgE response to selected antibiotics such as penicilloyl G, penicilloyl V, amoxicillin, ampicillin, cephalosporin, doxycycline, tetracycline, ciprofloxacin and others.
  • Painkiller and anti-inflammatory drug sensitivity: Checks IgE response to medicines such as paracetamol, diclofenac, ibuprofen, piroxycam and pyrazolone.
  • Local anaesthetic sensitivity: Checks IgE response to lidocaine, benzocaine, mepivacaine and prilocaine.
  • Hormone and steroid related sensitivity: Includes insulin human, cortisone and prednisolone.
  • Other medicine sensitivity: Includes theophylline, ambroxol, pyridoxamine (Vitamin B6) and cobalamin (Vitamin B12).
  • Allergy risk evaluation: Supports your doctor in understanding whether a drug specific IgE response may be contributing to your symptoms.

A positive result suggests sensitisation to a specific drug allergen. It does not always prove that the drug will cause a reaction in you. A negative result also does not completely rule out drug allergy, especially if the reaction was not IgE mediated or occurred long ago.

Drug Panel - Comprehensive (35Drugs), Serum: Who Needs It and Why It’s Done

What Symptoms May Call for a Drug Panel - Comprehensive (35Drugs), Serum?

Your doctor may recommend this test if you have had symptoms after taking a medicine, such as:

  • Hives, itching, redness, or raised skin rashes
  • Swelling of the lips, eyelids, face, tongue, or throat
  • Wheezing, chest tightness, coughing, or breathing difficulty
  • Sudden dizziness, faintness, or a drop in blood pressure after medicine intake
  • Repeated reactions after taking the same or similar medicine
  • Suspected allergy after antibiotics, painkillers, local anaesthetics, insulin, steroids, or other medicines
  • Unclear drug reaction history where further allergy evaluation is needed

Seek emergency care immediately if you develop breathing difficulty, throat swelling, severe dizziness, or symptoms of anaphylaxis after taking any medicine.

Who Should Get a Drug Panel - Comprehensive (35Drugs), Serum?

  • People with a past suspected allergic reaction to a medicine
  • People with repeated reactions after taking specific drugs
  • People who need drug allergy evaluation before future treatment planning
  • Patients with suspected antibiotic allergy
  • Patients with suspected painkiller or anti-inflammatory medicine allergy
  • People who may need local anaesthesia but have a history of suspected anaesthetic reaction
  • People with multiple reported drug allergies who need structured allergy evaluation
  • Patients advised by an allergist, physician, surgeon, dentist, or anaesthetist before planned treatment

Why is a Drug Panel - Comprehensive (35Drugs), Serum Done?

The test is done to detect drug allergen specific IgE antibodies that may support the evaluation of immediate drug allergy. It helps your doctor identify possible drug sensitivities and plan safer treatment options.

Importance of Drug Panel - Comprehensive (35Drugs), Serum

Drug allergies can affect future treatment choices. If a suspected allergy is not evaluated properly, you may avoid medicines unnecessarily or may be exposed to a medicine that could trigger another reaction.

The Drug Panel - Comprehensive (35Drugs), Serum helps your doctor assess IgE related sensitisation to a broad set of commonly used medicines. It can support decisions about drug avoidance, alternative medicines, allergy referral and further testing. Your result should always be reviewed with your reaction history, the timing of symptoms, the dose taken, other medicines used at the same time and your overall health condition.

Drug Panel - Comprehensive (35Drugs), Serum Booking & Reports - Metropolis Healthcare

How to Book the Drug Panel - Comprehensive (35Drugs), Serum and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Drug Panel - Comprehensive (35Drugs), Serum, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the Lab.
  2. Safe Home Sample Collection
    Our trained phlebotomists ensure timely collection of your sample while strictly following all safety and hygiene protocols.
  3. Sample Tracking Updates
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories, where expert technicians ensure accurate results.
  5. Quick and Easy Reports
    Receive your test reports via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.

Is Home Sample Collection for Drug Panel - Comprehensive (35Drugs), Serum Available Near You?

Yes, Metropolis Healthcare offers home sample collection for Drug Panel - Comprehensive (35Drugs), Serum. This service saves you time, reduces the need for travel, and ensures professional blood sample collection while maintaining strict safety and quality standards.

In how much time will I get Drug Panel - Comprehensive (35Drugs), Serum report?

Reports are usually available on the same day once the sample reaches the lab.

Note: Reporting time and cost may vary based on your location.

Where can I see or get Drug Panel - Comprehensive (35Drugs), Serum results?

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp and you also have the option to collect a physical copy directly from the Lab.

Interpreting Drug Panel - Comprehensive (35Drugs), Serum Results

What Your Drug Panel - Comprehensive (35Drugs), Serum Results May Indicate

Your report shows the concentration of drug allergen specific IgE for each tested drug allergen. Your doctor will interpret these results with your reaction history, symptoms, timing of medicine intake and other clinical findings.

Specific IgE Concentration Class Interpretation
<0.36 IU/mL 0 Clinically insignificant
0.36-0.71 IU/mL 1 Very Low
0.72-3.59 IU/mL 2 Low
3.60-17.99 IU/mL 3 Medium
18.00-49.99 IU/mL 4 High
50.00-100 IU/mL 5 Very High
>100 IU/mL 6 Extremely High

 

Negative results do not necessarily rule out drug allergy. False negative results may occur if there has been no recent exposure, if certain medicines interfere with testing, or if the level of measurable IgE has reduced over time after the allergic reaction.

Understanding Abnormal Drug Panel - Comprehensive (35Drugs), Serum Results by Parameter

Parameter Group Parameters Included Positive Result May Indicate Negative Result May Indicate
Pain and inflammation related drug allergens Paracetamol, Pyrazolone, Piroxycam, Diclofenac, Ibuprofen IgE sensitisation to one or more tested pain or inflammation related drug allergens No detectable IgE sensitisation to the tested drug allergen, though allergy is not fully ruled out
Local anaesthetic related drug allergens Lidocaine, Benzocaine, Mepivacaine, Prilocaine IgE sensitisation to one or more tested local anaesthetic related allergens No detectable IgE sensitisation to the tested drug allergen
Penicillin and related antibiotic allergens Penicilloyl G, Penicilloyl V, Ampicillin, Amoxicillin, Cloxacillin, Oxacillin IgE sensitisation to one or more tested penicillin related drug allergens No detectable IgE sensitisation to the tested drug allergen
Cephalosporin related allergen Cephalosporin IgE sensitisation to the tested cephalosporin allergen No detectable IgE sensitisation to this tested allergen
Other antibiotic related allergens Doxycycline, Neomycin, Chloramphenicol, Metronidazole, Tetracycline, Gentamycin, Erythromycin, Streptomycin, Trimethoprim, Sulfamethoxazole, Ciprofloxacin, Sulfa Antibiotic IgE sensitisation to one or more tested antibiotic related drug allergens No detectable IgE sensitisation to the tested drug allergen
Hormone and steroid related allergens Insulin Human, Cortisone, Prednisolone IgE sensitisation to one or more tested hormone or steroid related allergens No detectable IgE sensitisation to the tested drug allergen
Other tested drug allergens Theophylline, Ambroxol, Pyridoxamine (Vitamin B6), Cobalamin (Vitamin B12) IgE sensitisation to one or more of these tested drug allergens No detectable IgE sensitisation to the tested drug allergen

 

A positive result should not make you stop or restart any medicine on your own. Your doctor will decide the next steps based on your result, reaction severity and future treatment needs.

How Should You Prepare for a Drug Panel - Comprehensive (35Drugs), Serum?

The Drug Panel - Comprehensive (35Drugs), Serum requires minimal preparation. Follow these simple steps before your blood test:

  • No fasting required: You can eat and drink normally before the test.
  • Share your drug reaction history: Inform your doctor about the medicine you took, when you took it and what symptoms you developed.
  • Carry previous records: Bring earlier prescriptions, discharge summaries, allergy cards, emergency treatment notes, or previous allergy test reports if available.
  • List all medicines: Tell your doctor about all current medicines, supplements, injections, inhalers and over the counter drugs you take.
  • Do not self challenge: Do not take a suspected medicine again to check your reaction unless your doctor specifically supervises it.
  • Mention severe reactions: Tell your doctor if you have ever had breathing difficulty, throat swelling, fainting, or anaphylaxis after taking any medicine.
  • Stay normally hydrated: Drink water as usual before sample collection.

How Is a Drug Panel - Comprehensive (35Drugs), Serum Done? (Step-by-Step Procedure)

The Drug Panel - Comprehensive (35Drugs), Serum is performed using a simple blood collection process:

  • Preparation: An elastic band is tied around your upper arm to make the veins more visible.
  • Cleaning: The puncture site is cleaned with an antiseptic solution.
  • Blood Draw: A sterile needle is inserted into your vein to collect the blood sample.
  • Sample Collection: About 3 ml of blood is collected in a gel vacutainer.
  • Completion: The needle is removed, and a bandage is applied to the site.
  • Processing: Your serum sample is tested using Enzyme Immunoassay (EIA) to measure drug allergen specific IgE antibodies.

Conditions That May Affect Drug Panel - Comprehensive (35Drugs), Serum Accuracy

Several factors can influence how your Drug Panel - Comprehensive (35Drugs), Serum results are interpreted:

  • No recent exposure: Specific IgE may be low or undetectable if you have not been exposed to the suspected drug recently.
  • Time since reaction: Drug specific IgE levels may decrease over time after an allergic reaction.
  • Reaction type: Not all drug reactions are IgE mediated, so this test may not detect every type of drug hypersensitivity.
  • Certain medicines: Some medicines may interfere with immune response or result interpretation, so share your full medication list with your doctor.
  • Cross reacting substances: Reactions to related medicines or similar chemical structures may affect interpretation.
  • Clinical history mismatch: A positive result suggests sensitisation, but it does not always prove that the drug caused your symptoms.
  • Need for specialist review: Your doctor may advise additional tests, supervised challenge, or allergy specialist consultation depending on your history.

Diseases That A Drug Panel - Comprehensive (35Drugs), Serum Can Help Detect

  • Drug allergy: An immune reaction to a medicine.
  • Immediate drug hypersensitivity: A reaction that may occur soon after taking a medicine and may involve IgE antibodies.
  • Antibiotic allergy: Suspected allergy to medicines such as penicillins, cephalosporins, sulfa antibiotics, quinolones, or other antibiotics in the panel.
  • Painkiller related allergy: Suspected allergic sensitivity to selected pain or anti-inflammatory medicines.
  • Local anaesthetic allergy evaluation: Suspected sensitivity to medicines used for numbing during dental or minor procedures.
  • Medicine related urticaria: Hives or itchy raised skin patches after medicine exposure.
  • Medicine related angioedema: Swelling of the lips, eyelids, face, tongue, or throat after medicine exposure.
  • Anaphylaxis risk evaluation: Supports investigation in people with a history of severe immediate reactions to medicines.

References

  1. Demoly P, Adkinson NF, Brockow K, Castells M, Chiriac AM, Greenberger PA, et al. International Consensus on drug allergy. Allergy. 2014;69(4):420-437. PMID:24697291.
  2. Brockow K. Detection of drug-specific immunoglobulin E (IgE) and acute mediator release for the diagnosis of immediate drug hypersensitivity reactions. J Immunol Methods. 2021;496:113101. PMID:34273396.
  3. Van Gasse AL, Ebo DG, Faber MA, Elst J, Bridts CH, Mertens C, et al. Serum specific IgE antibodies in immediate drug hypersensitivity. Clin Chim Acta. 2020;504:119-124. PMID:32035852.
  4. Broyles AD, Banerji A, Castells M. Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: General Concepts. J Allergy Clin Immunol Pract. 2020;8(9S):S3-S15. PMID:32791249.
  5. Broyles AD, Banerji A, Barmettler S, Biggs CM, Blumenthal K, Brennan PJ, et al. Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. J Allergy Clin Immunol Pract. 2020;8(9S):S16-S116. PMID:33039006.
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Drug Panel - Comprehensive (35Drugs), Serum Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Drug Panel - Comprehensive (35Drugs), Serum with a clear pricing structure.

The Drug Panel - Comprehensive (35Drugs), Serum Price in Mumbai is ₹ 17,500 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

You can take this test when your doctor recommends it after a suspected drug reaction. Testing is most useful when your reaction history, timing and suspected medicine details are clearly shared with your doctor.

No, overnight fasting is not required. You can eat and drink normally before the test unless your doctor has advised fasting for another test.

Mild dehydration usually does not directly affect drug specific IgE results. However, normal hydration can make blood collection easier and more comfortable.

No special diet is needed. Inform your doctor about all medicines, supplements, injections and previous drug reactions. Do not stop or restart any medicine unless your doctor advises you.

A phlebotomist cleans the skin, inserts a sterile needle into a vein in your arm and collects about 3 ml of blood in a gel vacutainer. The sample is then sent to the lab for EIA testing.

The risks are minimal and similar to any routine blood test. You may feel slight pain, mild bruising, or dizziness during or after sample collection. Serious complications are rare.

A result below 0.36 IU/mL is reported as negative and clinically insignificant for the tested drug allergen. A result of 0.36 IU/mL or above is positive and should be interpreted by your doctor with your reaction history.

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