AChR- Acetyl Choline Receptor Antibodies Test - Metropolis Healthcare
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AChR- Acetyl Choline Receptor Antibodies Test

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This test detects and measures Acetylcholine Receptor antibodies in the blood.

Sorry, this test is not available to book.

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Blood Collection at Home
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    To help diagnose a condition called “myasthenia gravis (MG)” that results from the immune attack to the receptors, and to distinguish between MG and other conditions with overlapping symptoms.

Your doctor may recommend this test for you if you are suffering from myasthenia gravis (MG). the symptoms include:

  • Shortness of breath.
  • Trouble while speaking
  • Baggy eyelids.
  • Unsteady walk.
  • Weakness in the arms, legs, neck, and fingers.

Acetylcholine receptor (AChR) antibodies are antibodies produced by the immune against its own proteins system (called autoantibodies), mistakenly produced by the immune system to target proteins called acetylcholine receptors that are located on skeletal muscles. This test checks and measures AChR antibodies in the blood.

Reference Values Of AChR- Acetyl Choline Receptor Antibodies Test

Interpretation

Value nmol/L

Normal Level

0-0.25

Borderline level

0.26-0.40

Positive level

 > 0.4

Interpretations

Normally, AChR antibodies aren’t present in the blood. They are autoantibodies, with their presence in the blood indicative of an autimmune response-where the body mistakenly produces antibodies targeted against its own components. If a person presents with these antibodies along with symptoms of MG, then the patient is most likely a victim of this disease.

However, a negative test result does not rule out MG. Literally half of the cases of ocular MG (affecting only eye-related muscles) and about 10-15% of those with generalized MG show negative results for AChR antibodies. Results from other tests for autoantibodies, such as anti-MuSK (muscle-specific kinase) antibody test and anti-striated muscle antibody test, may help in definitive diagnosis. As high as 70% of people suspected to have generalized MG but who are negative for AChR antibodies will be positive for anti-MuSK antibodies.

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AChR- Acetyl Choline Receptor Antibodies Test

3300