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Liver Function Test-1 (Maxi)

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Liver Profile Test Overview

Liver function tests (LFT) are done to detect liver disease and assess improvement with treatment. It measures enzymes, proteins produced by liver and also assesses its ability to clear bilirubin

The liver is the second largest organ after the skin. It lies in the right upper abdomen below the right lung. The main two functions of the liver include - detoxification of your body and digestion of the food you consume. This test makes a doctor understand the extent of liver disease, liver damage, and associated disorders. The parameters of the test include liver enzymes and proteins in the blood. 

The Liver Function Maxi test measures the extent of liver infection or damage and the progression of the disease. It also checks the suitability of the treatment for the patient.

  1. Bilirubin (Direct): It is a liver enzyme marker. This red-orange colour pigment undergoes chemical changes in the liver. It gets transferred to the intestines to remove through the stools.
  2. Bilirubin (Total): This test measures the total amount of Bilirubin in the blood. It measures both Direct Bilirubin and Indirect Bilirubin. Indirect Bilirubin comes from the breakdown of red blood cells. It travels in the blood to the liver.
  3. AST: Aspartate transaminase, formerly known as SGOT, or Serum glutamic-oxaloacetic transaminase, is one of the two liver enzymes.
  4. ALT: Alanine transaminase, formerly known as SGPT, or Serum glutamic-pyruvate transaminase, is one of the two liver enzymes.
  5. Total Proteins: Proteins make up the skeleton of the whole body. The two kinds of proteins in the body are Albumin and Globulin.
  6. Albumin: It is a protein made in the liver. It checks the condition of your liver and kidneys.

ALP: Alkaline phosphatase is an enzyme in the blood. It helps in protein breakdown

Who should do the liver function maxi test?

People with the following medical conditions should do the liver function maxi test:

  • Diabetes
  • Liver Cancer
  • Wilson's Disease
  • Hemochromatosis
  • Toxic Hepatitis
  • Jaundice
  • Hepatitis A, B, and C
  • Cirrhosis
  • Fatty Liver
  • Alcoholic Hepatitis
  • Non-alcoholic Hepatitis
  • Hemochromatosis. 

Doctors advise the liver function maxi test for people with lifestyle issues such as:

  • Alcohol
  • obesity
  • tattoos
  • piercings
  • blood transfusion
  • unprotected exposure to other people's blood Or body fluids like semen, urine, or sweat
  • type 2 diabetes mellitus

Written by: Dr Vishal Wadhwa, M.D, D.N.B Microbiology, Medical Affairs

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Liver Function Test-1 (Maxi) Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Liver Function Test-1 (Maxi) with a clear pricing structure.

The Liver Function Test-1 (Maxi) Price in Mumbai is ₹ 1,475 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

LFT are used to assess function of liver which may be altered during liver infections, non-infectious conditions or injury. This test is not usually a part of battery of other tests recommended to diagnose a disease.
LFT can be used to monitor progression of diseases i.e., viral or alcoholic hepatitis, and their response to treatment
It is also done to monitor side effects of medications i.e., Isoniazid, Rifampicin & Pyrazinamide treatment for tuberculosis

A liver function maxi test is done to:

• Measure the levels of liver enzymes in case of liver diseases like fatty liver, cirrhosis, alcoholic hepatitis, or jaundice.

• Evaluate your risk of liver disease, damage, or any other ailment.

• Measure the level of the six liver components:

  1. Bilirubin (Direct)
  2. Bilirubin (Total)
  3. AST
  4. ALT
  5. Total Proteins
  6. ALP

• To assess the ability of the liver to excrete bilirubin

• Check if the treatment is suitably working for you or not.

Liver profile test measures bilirubin levels (direct, total), AST, ALT, total proteins, albumin, ALP

Liver Profile test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

The laboratory technician will tie an elastic band on your upper arm during the test. Then they will ask you to form a fist with your hand. This helps with the build-up of blood in the veins. They will then disinfect the area before inserting a needle into a vein in your arm to extract blood. They will collect the blood into an attached vacutainer or collection tube. They will then send it to the laboratory for analysis.

Ideally all parameters should be within the biological reference range. High levels are associated with certain diseases.
High ALT is associated with liver damage
High AST is associated with liver, muscle or other organ damage or disease. In isolated liver damage rise in ALT n AST is disproportionate to ALP 
High ALP is associated with blocked bile duct, or certain bone diseases and rise in such conditions is disproportionate to AST & ALT
Low proteins may be associated with liver disease or damage
High bilirubin might indicate liver damage (increase in direct bilirubin) or disease or certain types of anaemia (increase in indirect bilirubin)
High GGT may indicate bile duct damage. It may increase in hepatitis, liver cancer, acute heart condition. But together with ALP can help pinpoint liver related disorders
High Prothrombin time may be due deficiency of coagulation factors or due to deficiency of Vitamin K or due to anticoagulants being administered
LDH is increased in diseases involving blood (megaloblastic & pernicious anaemia), heart, liver, lung, kidney and other organs. In Hodgkin's disease and multiple myeloma

The liver function maxi test requires 10-12 hours of fasting. Your doctor may ask you to stop taking your medications before the test.

Bilirubin is measured in milligrams per decilitre of blood. A value less than 1.2 mg/dl is normal.

Bilirubin - Direct: 0.0 to 0.3 mg/dL

Bilirubin - Total: 0.0 to 1.2 mg/dL

AST: 8 to 48 U/L

ALT: 7 to 55 U/L

Total Proteins: 6.3 to 7.9 g/dL

Albumin: 3.5 to 5 g/dL

ALP: 40 to 129 U/L

These are the ranges of test values for adults.

  • Avoid smoking
  • Avoid drinking alcohol
  • Lose the excessive weight
  • Regularly exercise
  • Drink coffee
  • Avoid junk foods high in cholesterol
  • Increase folic acid-rich foods

Warning signs of a liver ailment include -

  • yellow skin and eyes
  • abdominal pain and swelling
  • chronic weakness
  • dark urine
  • Pale-coloured stools
  • Itching of the skin
  • swelling in ankles and feet

LFT

Liver Panel

Liver Chemistries

Liver Function Panel

Liver Profile

Prothrombin Time

Bilirubin Total

Bilirubin Direct

Bilirubin Indirect

Serum Glutamic-oxaloacetic Transaminase (SGOT)

Aspartate Transaminase (AST)

Serum Glutamic-pyruvic Transaminase (SGPT)

Alanine Transaminase (ALT)

Gamma Glutamyl Transpeptidase (GGTP)

Proteins

Alkaline Phosphatase (ALP)

Lactate Dehydrogenase (LDH)

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