Urea Clearance Test

The Urea Clearance Test measures how effectively your kidneys filter blood and remove urea from it.

• To evaluate kidney function in patients with suspected renal disease
• To monitor kidney function in patients with known renal disease
• To monitor the effectiveness of dialysis treatment
• To diagnose and monitor other conditions that affect kidney function, such as high blood pressure or diabetes

The Urea Clearance Test may be recommended to you in the following cases:

• Symptoms of kidney disease such as frequent urination, painful urination, fatigue, nausea, or swelling in legs or feet
• Medical history of diabetes, high blood pressure, or family history of kidney disease.
• If you have a kidney transplant

A normal urea clearance rate is 60 to 120 milliliters per minute (mL/min). A lower urea clearance rate indicates that your kidneys are not working as well as they should. Abnormal levels may indicate chronic kidney disease, acute renal failure, nephritis, urinary tract obstruction, decreased blood flow to kidneys, or other kidney-related problems.

A technician will draw a blood sample from a vein in your arm. They will also ask you to provide 24-hour urine samples. This means that you will need to collect all of your urine for 24 hours and store it in a special container. Once you have collected your urine and blood samples, they will be sent to a laboratory for analysis. The laboratory will measure the amount of urea in your urine and blood. They will also calculate your urea clearance rate.

• Avoid consuming high-protein foods and certain medications for at least 24 hours before the test.
• Your doctor may ask you to come to the lab with a full bladder to give your urine sample right away.
• Your doctor may also suggest not consuming any caffeine or alcohol for the 24-hour period before the test.
• Inform your doctor if you have any specific requirements.

Creatinine Blood Test: Measures the amount of waste product creatinine in the blood.

Renal Function Tests: A group of tests that evaluate kidney function, including blood urea nitrogen (BUN), creatinine clearance, and urinalysis.

Urea Nitrogen Serum or Blood Urea Nitrogen (BUN) Test

Chronic kidney disease occurs when your kidneys gradually lose function over time, rendering them unable to filter waste products from your body effectively. It may occur due to high blood pressure, diabetes or other underlying medical conditions and can lead to heart disease and other complications if left untreated. Symptoms include fatigue, swelling in legs, frequent urination, and nausea.