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Thyroid Comprehensive Profile 1 Test
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Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
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Thyroid Comprehensive Profile 1 Test Details in Brief
| Also Known As | Thyroid Function Test (TFT) with Antibodies, Extended Thyroid Panel, Thyroid Profile - Comprehensive |
|---|---|
| Purpose | Includes TSH, free T3, free T4, and thyroid antibodies, aids in evaluating overall thyroid function, supports diagnosis and management of hypothyroidism and hyperthyroidism. |
| Preparation | Clinical history required, high biotin dose (>5 mg/day) should be avoided at least 8 hrs before blood collection. |
| Fasting | Not required |
| Reporting Time | After 6 hrs |
| Cost | 2,850 |
What is a Thyroid Comprehensive Profile-1 Test?
The thyroid comprehensive profile-1 test is a comprehensive panel of blood tests that provides a detailed assessment of your thyroid gland function. The test helps diagnose and monitor thyroid disorders, such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid), and can identify autoimmune health conditions affecting your thyroid gland.
What does the Thyroid Comprehensive Profile-1 Test measure?
This comprehensive test measures several key substances in your blood to give a complete picture of your thyroid health:
- Thyroid-Stimulating Hormone (TSH): Acts as a signal from your brain to tell the thyroid gland to produce hormones.
- Total Thyroxine (T4): The main hormone produced by your thyroid gland, measured in its complete form.
- Free T4: The active portion of the T4 hormone that is available for your body to use.
- Total Triiodothyronine (T3): The more active form of thyroid hormone that affects cells throughout your body.
- Free T3: The active portion of the T3 hormone available for immediate use.
- Anti-Thyroid Peroxidase (Anti-TPO) Antibodies: Checks if your immune system is attacking a crucial thyroid enzyme.
- Anti-Thyroglobulin (Anti-Tg) Antibodies: Measures antibodies against thyroglobulin, a protein in your thyroid gland.
Thyroid Comprehensive Profile-1 Test: Who Needs It and Why It's Done
What Symptoms May Call for a Thyroid Comprehensive Profile-1 Test?
Your doctor may recommend this test if you experience persistent symptoms related to thyroid dysfunction:
Symptoms of Underactive Thyroid (Hypothyroidism):
- Unexplained weight gain or difficulty losing weight
- Constant tiredness, fatigue, and lethargy
- Dry skin and hair fall
- Feeling cold when others do not
- Constipation
- Irregular or heavy menstrual periods in women
- Mood swings or depression
- Hoarseness of voice
Symptoms of Overactive Thyroid (Hyperthyroidism):
- Unexplained weight loss despite normal appetite
- Anxiety, nervousness, and irritability
- Rapid or irregular heartbeat (palpitations)
- Tremors in hands and fingers
- Increased sweating and sensitivity to heat
- More frequent bowel movements
- Bulging eyes
- Disturbed sleep
Who should get a thyroid comprehensive profile-1 test?
Several groups of people may benefit from this comprehensive thyroid assessment:
- Patients with symptoms: Anyone experiencing the thyroid-related symptoms mentioned above.
- High-risk individuals: People with a family history of thyroid disorders or other autoimmune conditions.
- Women: Especially those who are pregnant, planning pregnancy, or have recently given birth.
- People on thyroid medication: To monitor treatment effectiveness and ensure proper dosage.
- Preventive health checkups: Often included in annual full-body checkups, particularly for women over 35.
Why is a thyroid comprehensive profile-1 test done?
This test is performed to accurately diagnose the root cause of thyroid-related symptoms, confirm or rule out thyroid disorders, and guide your doctor in creating the most effective treatment plan for your specific condition.
Importance of a Thyroid Comprehensive Profile-1 Test
The thyroid comprehensive profile-1 test is clinically significant because it provides a complete evaluation of your thyroid health. Unlike basic screening tests, this comprehensive panel can identify autoimmune causes of thyroid dysfunction by measuring specific antibodies. This distinction is crucial because autoimmune conditions like Hashimoto's disease require lifelong monitoring and specific management approaches.
The test results directly influence treatment decisions and help your doctor distinguish between different types of thyroid disorders, ensuring you receive the most appropriate care for your condition.
Thyroid Comprehensive Profile-1 Test Booking & Reports – Metropolis Healthcare India
How to Book a Thyroid Comprehensive Profile-1 Test?
- Simple Online Booking
Booking can be done through the Metropolis Healthcare App or website. Select the Thyroid Comprehensive Profile-1 test, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab. - Safe Home Sample Collection
Our trained phlebotomists ensure the timely collection of your sample while strictly following all safety and hygiene protocols. - Sample Tracking Updates
Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website. - Accurate Laboratory Testing
Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results. - Quick & Easy Reports
Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is home sample collection for the Thyroid Comprehensive Profile-1 Test available near you?
Yes, home blood sample collection for the thyroid comprehensive profile-1 test is available at Metropolis Healthcare. Our trained phlebotomists follow strict safety protocols while collecting your blood sample in the comfort of your home. This service eliminates the need to travel to a pathology lab, making health monitoring more accessible for you and your family.
How Long Does It Take to Get a Thyroid Comprehensive Profile-1 Test Report?
Reports are usually available after 6 hours once the sample reaches the lab.
Where can I see or get Thyroid Comprehensive Profile-1 Test results?
Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.
Interpreting Thyroid Comprehensive Profile-1 Test Results
What Your Thyroid Comprehensive Profile-1 Test Results May Indicate
The following table provides guidance on understanding your test results and what different values may suggest:
|
Parameters |
Normal Range |
High Values May Indicate |
Low Values May Indicate |
|
T3 (Total) |
84.6-201.8 ng/dL First Trimester: 104.8 - 229.8 ng/dL Second Trimester: 128.9 - 262.3 ng/dL Third Trimesters: 135.4 - 261.7 ng/dL |
Hyperthyroidism, thyroid hormone resistance |
Hypothyroidism, non-thyroidal illness |
|
Free T3 |
2.0-4.4 pg/mL First Trimester: 2.46 - 3.49 pg/mL Second Trimester: 2.09 - 3.55 pg/mL Third Trimester: 2.01 - 3.27 pg/mL |
Hyperthyroidism, T3 toxicosis |
Hypothyroidism, severe illness |
|
T4 (Total) |
5.1-14.1 μg/dL First Trimester: 7.33 - 14.8 μg/dL Second Trimester: 7.93 - 16.1 μg/dL Third Trimester : 6.95 - 15.7 μg/dL |
Hyperthyroidism, increased binding proteins |
Hypothyroidism, decreased binding proteins |
|
Free T4 |
0.93-1.7 ng/dL First Trimester: 0.7-2.0 ng/dL Second Trimester: 0.5-1.6 ng/dL Third Trimester: 0.5-1.6 ng/dL |
Hyperthyroidism, excessive thyroid medication |
Hypothyroidism, inadequate thyroid medication |
|
TSH (Ultrasensitive) |
0.54-5.3 μIU/mL First Trimester: 0.33-4.59 μIU/mL Second Trimester: 0.35-4.10 μIU/mL Third trimester: 0.21-3.15 μIU/mL |
Hypothyroidism, thyroid gland dysfunction |
Hyperthyroidism, pituitary disorders |
|
Microsomal (TPO) Antibody Titre, Serum |
<= 5.61 IU/mL |
Hashimoto's thyroiditis, Graves' disease, autoimmune thyroid conditions |
Generally not clinically significant |
|
Thyroglobulin Antibody (ATG), Serum |
<= 4.11 IU/mL |
Hashimoto's thyroiditis, autoimmune thyroid disorders |
Generally not clinically significant |
Conditions that May Affect Thyroid Comprehensive Profile-1 Test Accuracy
Several factors can influence your thyroid comprehensive profile-1 test results and should be discussed with your doctor:
- High-dose biotin supplements (more than 5 mg per day) can interfere with test results and should be stopped at least 8 hours before blood collection.
- Certain medications, including lithium, amiodarone, L-DOPA, and glucocorticoids, can affect thyroid hormone levels.
- Pregnancy can alter thyroid hormone levels and antibody titres.
- Severe illness, infections, liver disease, kidney failure, and major surgery can cause transient changes in thyroid function.
- The time of blood collection matters as TSH levels naturally fluctuate throughout the day.
- Iodine intake from dietary sources or contrast agents can temporarily affect thyroid function.
How is a Thyroid Comprehensive Profile-1 Test Done?
The thyroid comprehensive profile-1 test involves a simple blood collection procedure:
- A healthcare professional cleans an area on your arm, usually the inside of your elbow, with an antiseptic.
- An elastic band (tourniquet) is tied around your upper arm to make the veins more visible.
- A small needle is inserted into the vein to collect approximately 3 ml of blood in a gel vacutainer.
- The needle is removed, and a cotton ball or bandage is placed on the spot to stop any bleeding.
- Your blood sample is then sent to our NABL & CAP accredited laboratory for analysis using the electrochemiluminescence immunoassay (ECLIA) method.
- The entire process takes just a few minutes and causes minimal discomfort.
How Should You Prepare for a Thyroid Comprehensive Profile-1 Test?
Preparing for your thyroid comprehensive profile-1 test is straightforward:
- No fasting required - You can eat and drink normally before the test.
- Stop high-dose biotin supplements - Avoid taking biotin supplements exceeding 5 mg daily for at least 8 hours before blood collection.
- Inform about medications - Tell your doctor about all medicines and supplements you are currently taking.
- Consider timing - Early morning blood collection is preferred as TSH levels are naturally highest at this time.
- Stay hydrated - Drink a normal amount of water unless instructed otherwise.
- Discuss thyroid medication timing - If you take thyroid medication, ask your doctor whether to take it before or after the blood draw.
Diseases that a Thyroid Comprehensive Profile-1 Test Can Help Detect
This comprehensive test can help identify several thyroid-related conditions:
- Hashimoto's thyroiditis - The most common cause of hypothyroidism, characterised by high TPO antibodies.
- Graves' disease - An autoimmune condition causing hyperthyroidism.
- Primary hypothyroidism - Underactive thyroid gland with elevated TSH and low thyroid hormones.
- Primary hyperthyroidism - Overactive thyroid gland with suppressed TSH and high thyroid hormones.
- Subclinical thyroid dysfunction - Early-stage thyroid problems with normal hormone levels but abnormal TSH.
- Autoimmune thyroid disorders - Conditions where the immune system attacks the thyroid gland.
- Secondary thyroid disorders - Thyroid problems caused by pituitary gland dysfunction.
Thyroid Comprehensive Profile-1 Test/Packages that You Can Book With Metropolis Healthcare
Metropolis Healthcare offers several related thyroid tests and packages to meet your specific health needs:
|
Test/Package Name |
Purpose/Highlights |
|
Extended thyroid assessment with additional parameters |
|
|
Basic thyroid function evaluation with FT3, FT4, and TSH |
|
|
Comprehensive thyroid testing with reflexive additional tests based on initial results |
|
|
Specific testing for autoimmune thyroid conditions |
Thyroid Comprehensive Profile-1 Test Prices in Different Cities
The cost of a thyroid comprehensive profile-1 test may vary depending on your location. Here's a table showing the approximate prices in different cities:
|
City |
Price |
|
₹2500 to ₹3500 |
|
|
₹2500 to ₹3500 |
|
|
₹2500 to ₹3500 |
|
|
₹2500 to ₹3500 |
|
|
₹2500 to ₹3500 |
|
|
₹2500 to ₹3500 |
Reference:
- Clinical Chemistry 50:12, 2338-2344 (2004) and Ind J Clin Biochem (Apr-June 2014) 29(2):189–195.
- Ref: Arch Pathol Lab Med—Vol 141, November 2017.
- Fisher DA. Physiological variations in thyroid hormones: physiological and pathophysiological considerations. Clin Chem.1996 Jan;42(1):135-9. PMID: 8565215
Thyroid Comprehensive Profile 1 Test Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Thyroid Comprehensive Profile 1 Test with a clear pricing structure.
The Thyroid Comprehensive Profile 1 Test Price in Mumbai is ₹ 2,850 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
The best time for blood collection is early morning when TSH levels are naturally at their highest. This timing helps ensure the most accurate results for thyroid function assessment.
Fasting is not required for thyroid hormone tests. However, if your test is combined with other blood tests that require fasting, your doctor will inform you accordingly.
Severe dehydration can concentrate blood substances and potentially affect test accuracy. It's recommended to maintain normal hydration levels by drinking adequate water before your blood collection.
No special diet is needed. However, stop high-dose biotin supplements (over 5 mg daily) at least 8 hours before testing. Inform your doctor about all medications you're taking.
A trained phlebotomist cleans your arm, applies a tourniquet, inserts a small needle into your vein, and collects about 3 ml of blood. The process takes just a few minutes.
Health risks are minimal and similar to any blood test. You may experience slight pain, bruising at the needle site, or, rarely, dizziness. Infection risk is extremely low with proper procedures.
Normal ranges vary and depend on factors like age, gender, and pregnancy status. Typical normal ranges include TSH: 0.54-5.3 μIU/mL, Total T4: 5.1-14.1 μg/dL, and Total T3: 84.6-201.8 ng/dL. Your report will include specific reference ranges, and your doctor will interpret results appropriately.
This test is also called Thyroid Function Test (TFT) with Antibodies, Extended Thyroid Panel, or Thyroid Profile - Comprehensive.
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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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