Non Invasive Prenatal Screening NIPT Test in Piplod

What Does an NIPT Test Measure in Surat?

The NIPT Test measures chromosomal risk by analysing cell-free DNA in your blood:

• Trisomy 21 screening: Helps assess the chance of Down syndrome.
• Trisomy 18 screening: Helps assess the chance of Edwards syndrome.
• Trisomy 13 screening: Helps assess the chance of Patau syndrome.
• Sex chromosome aneuploidy screening: Helps assess the chance of conditions involving sex chromosomes, such as XO, XXX, XXY, XYY or XXYY.
• Foetal fraction: Shows the percentage of foetal or placental DNA present in your blood sample, which is important for reliable screening.
• Z score assessment: Helps the laboratory evaluate whether the chromosome signal falls within the expected reference interval.

Who Should Consider an NIPT Test?

You may be advised to consider an NIPT Test if your doctor wants a non-invasive screening option during pregnancy. It is especially useful for:

• Pregnant women who are 10 weeks of pregnancy or more, as advised by their doctor.
• Women with advanced maternal age.
• Women with a high-risk result on dual marker or quadruple marker screening.
• Women with ultrasound findings that need further genetic risk assessment.
• Women with a previous pregnancy affected by a chromosomal abnormality.
• Women who want an early, non-invasive screening test before considering invasive diagnostic procedures.
• Women who have been advised genetic counselling before or after prenatal screening.

What Is the Purpose of an NIPT Test?

The purpose of an NIPT Test is to help your doctor assess the chance of selected chromosomal abnormalities in your baby without using an invasive procedure. It supports informed pregnancy management and helps guide whether further diagnostic testing is needed.

NIPT can reduce unnecessary invasive testing in many low-risk cases, but it does not replace diagnostic tests when results are high risk or clinically unclear.

NIPT Test Booking & Reports: Metropolis Healthcare

How To Book NIPT Test with Metropolis Healthcare in Surat?

1. Simple Online Booking
   Booking can be initiated through the Metropolis Healthcare App or website. Select the NIPT Test, choose your preferred location, and follow the booking instructions. Since this test needs a special Streck tube and mandatory documents, home sample collection is not available for this test.
2. Document Readiness
   Keep your completed NIPT TRF and consent form ready. The form must include the clinician stamp. You also need your USG report, dual marker report, quadruple marker report and photo identification proof.
3. Scheduled Sample Collection
   Your maternal blood sample is collected as per the special collection requirements for NIPT. The sample must be collected in a Streck tube and handled according to the laboratory protocol.
4. Accurate Laboratory Testing
   Your sample is processed using Next Generation Sequencing in the molecular pathology testing pathway. This helps assess chromosomal risk with high analytical sensitivity.
5. Quick & Easy Reports
   Receive your test reports via email, WhatsApp, or by downloading them from the Metropolis Healthcare website or app.

How long does it take to get the NIPT Test report from Metropolis Healthcare in Surat?

Reports are usually available after 8 days once the sample reaches the lab.

Note: Reporting time and cost may vary based on your location.

Where can you view or collect your NIPT Test results?

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp and you also have the option to collect a physical copy directly from the lab.

Is home sample collection available for the NIPT Test in Surat near you?

No, home sample collection is not available for the NIPT Test in Surat. This test requires 10 ml maternal blood in a special Streck tube, along with a completed NIPT TRF, consent form, clinician stamp, USG report, marker screening reports and photo identification proof. Please follow the sample collection process advised by Metropolis Healthcare or your doctor.

Guide to Interpreting NIPT Test Results

What Your NIPT Test Results May Indicate

Your NIPT Test report gives a screening result. It does not confirm or rule out a condition with absolute certainty.

Understanding abnormal NIPT Test results by parameter ?

What Preparations Are Needed for an NIPT Test?

The NIPT Test needs a few important documents and simple preparation steps:

• No fasting required: You can eat and drink normally before the test.
• Carry mandatory documents: Bring your completed NIPT TRF and consent form with clinician stamp.
• Keep reports ready: Carry your USG report, dual marker report and quadruple marker report, if available.
• Carry photo ID proof: A valid photo identification document is required.
• Confirm pregnancy details: Share your gestational age, pregnancy status and clinical indication with your doctor or the sample collection team.
• Inform your doctor about special situations: Tell your doctor if you have a twin pregnancy, vanishing twin history, recent blood transfusion, organ transplant or any known chromosomal condition.
• Stay normally hydrated: Drink water as you usually do before the blood sample collection.

• Do not request foetal sex information: The NIPT Test does not reveal foetal sex as per Indian law.

NIPT Test Price in Different Cities

The cost of a NIPT Test may vary depending on your location. Here's a table showing the approximate price range for the NIPT Test at Metropolis Healthcare in major Indian cities:

The NIPT Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive NIPT Test prices across major cities in India.

References

1. Norton ME, Jacobsson B, Swamy GK, Laurent LC, Ranzini AC, Brar H, et al. Cell-free DNA analysis for noninvasive examination of trisomy. N Engl J Med. 2015;372(17):1589-1597. PMID:25830321.
2. Bianchi DW, Parker RL, Wentworth J, Madankumar R, Saffer C, Das AF, et al. DNA sequencing versus standard prenatal aneuploidy screening. N Engl J Med. 2014;370(9):799-808. PMID:24571752.
3. Gil MM, Accurti V, Santacruz B, Plana MN, Nicolaides KH. Analysis of cell-free DNA in maternal blood in screening for aneuploidies: updated meta-analysis. Ultrasound Obstet Gynecol. 2017;50(3):302-314. PMID:28397325.
4. Gregg AR, Skotko BG, Benkendorf JL, Monaghan KG, Bajaj K, Best RG, et al. Noninvasive prenatal screening for fetal aneuploidy, 2016 update: a position statement of the American College of Medical Genetics and Genomics. Genet Med. 2016;18(10):1056-1065. PMID:27467454.
5. Dungan JS, Klugman S, Darilek S, Malinowski J, Akkari YM, Monaghan KG, et al. Noninvasive prenatal screening for fetal chromosome abnormalities in a general-risk population: An evidence-based clinical guideline of the American College of Medical Genetics and Genomics. Genet Med. 2023;25(2):100336. PMID:36524989.