What does the Protein S Activity Test check for?

It measures how well Protein S helps prevent blood clots, identifying risk for conditions like DVT or PE.

Is fasting required before the Protein S Activity Test?

No fasting is needed before this test.

What does low Protein S activity mean?

It indicates Protein S deficiency, which may increase your risk of abnormal clot formation.

Can medication affect Protein S levels?

Yes, anticoagulants, contraceptives, and hormone therapy can affect Protein S activity.

Can Protein S deficiency be inherited?

Yes, it can be inherited or acquired due to conditions like liver disease or vitamin K deficiency.

How is the test sample collected?

A blood sample is collected from a vein and processed in frozen plasma for accurate testing.

When are test results available?

Reports are ready by the next day once the sample reaches the laboratory.

Protein S activity, Plasma in Hadapsar

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No special precautions

Sample Type

Blood

Recommended for

Male, Female

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Within 24 Hours

Blood test at Home

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Protein S Activity Test in Pune Details in Brief

Also Known As	Protein S Activity Functional Test, Protein S Functional Assay, Plasma Protein S Test
Purpose	To assess Protein S function and evaluate the risk of abnormal blood clotting (thrombosis)
Preparation	Inform your doctor about all medications and supplements before the test
Fasting	Fasting not required
Reporting Time	Next Day
Cost	4,970

Test Overview

What is a Protein S Activity Test in Pune?

The Protein S Activity Test in Pune helps assess how well your Protein S, a natural anticoagulant, functions to prevent excessive blood clotting. Protein S works together with Protein C to keep your blood flow balanced and prevent unwanted clots.

When Protein S levels or activity are low, your risk of developing deep vein thrombosis (DVT), pulmonary embolism (PE), or recurrent pregnancy loss increases.

This test uses a citrated plasma sample and measures the functional activity of Protein S using advanced coagulation techniques. It helps detect both inherited and acquired deficiencies, making it an essential test for individuals with clotting disorders or a family history of thrombosis.

What Does a Protein S Activity Test Measure in Pune?

The test measures the functional ability of Protein S to prevent blood clots. It helps your doctor:

Identify Protein S deficiency (a key cause of thrombophilia).
Assess patients with unexplained blood clots or pregnancy complications.
Distinguish between genetic and acquired causes of Protein S deficiency.
Evaluate risk in those with liver disease or on anticoagulant therapy.
Monitor women with recurrent miscarriage or preeclampsia.

Protein S Activity Test: Who Needs It and Why It’s Done

Who Should Get a Protein S Activity Test?

Unexplained or recurrent blood clots in veins or arteries.
DVT, pulmonary embolism, or family history of thrombophilia.
Pregnancy complications such as recurrent miscarriages.
Early onset stroke or heart attack.
Use of oral contraceptives or hormone therapy that increases clotting risk.

Why is a Protein S Activity Test Done?

The Protein S Activity Test helps identify individuals at increased risk of thrombosis due to inherited or acquired Protein S deficiency. It is vital for evaluating unexplained clotting, managing patients on anticoagulants, and assessing complications during pregnancy or surgery.

Protein S Activity Test Booking & Reports – Metropolis Healthcare

How to Book a Protein S Activity Test?

Book Easily Online
Visit the Metropolis Healthcare website or app and schedule your test at your preferred Metropolis lab.
Professional Sample Collection
A trained technician collects your blood sample using a 3.2% sodium citrate vacutainer for precise results.
Advanced Laboratory Testing
Samples are processed using state-of-the-art coagulation technology at NABL & CAP accredited labs.
Timely Reports
Reports are usually ready by the next day at 1:00 PM and can be accessed online or via email and WhatsApp.

In how much time will I get Protein S Activity Test report?

Reports are typically available the next day after your sample reaches the lab.
Note: Reporting time and cost may vary slightly based on your location.

Where can I see or get Protein S Activity Test results?

Your results can be accessed through the Metropolis Healthcare website, mobile app, email, or WhatsApp.

You can also collect a printed report from your nearest Metropolis laboratory in Pune.

Is Home Sample Collection for Protein S Activity Test Available Near You?

Home collection for this test is not available due to specific temperature and handling requirements. The sample must be collected and processed at the lab under controlled conditions to ensure accuracy.

Guide to Interpreting Protein S Activity Test Results

What Your Protein S Activity Test Results May Indicate

Parameter

Normal Range

Low Values May Indicate

High Values May Indicate

Protein S Activity

Non-Pregnant: 55–123%

1st Trimester: 57–95%

2nd Trimester: 42–68%

3rd Trimester: 16–42%

Protein S deficiency, thrombosis risk, or clotting disorder

Not clinically significant in most cases

Understanding Abnormal Protein S Activity Test Results by Parameter

Parameter	Low Value Interpretation	High Value Interpretation
Protein S Activity	Indicates inherited or acquired Protein S deficiency, associated with DVT, PE, and recurrent pregnancy loss	Typically normal or no major clinical concern

What Preparations Are Needed for a Protein S Activity Test?

To ensure accurate results:

No fasting required: You can eat and drink normally.
Inform your doctor: Share details of all medications, especially anticoagulants or contraceptives.
Provide full clinical history: Mention any prior DVT, stroke, or pregnancy issues.
Avoid delays: The plasma sample must be quickly frozen for precise analysis.

Protein S activity Test Price in Different Cities

The cost of a Protein S activity Test may vary depending on your location. Here's a table showing the approximate price range for the Protein S activity Test at Metropolis Healthcare in major Indian cities:

City	Approximate Cost (INR)
Mumbai	₹ 3900 to ₹ 4750
Delhi	₹ 3900 to ₹ 4750
Bengaluru	₹ 3900 to ₹ 4750
Chennai	₹ 3900 to ₹ 4750

The Protein S activity Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive Protein S activity Test prices across major cities in India.

References

Dahlbäck B. (2008). Advances in understanding Protein S and its role in anticoagulant function. Thrombosis and Haemostasis, 99(6), 1110–1115. PMID: 18521598
Esmon C.T. (2014). The protein C pathway: Regulation of hemostasis and thrombosis. Journal of Thrombosis and Haemostasis, 12(8), 1259–1272. PMID: 24862199
Rezende S.M., Simmonds R.E., Lane D.A. (2004). Coagulation, inflammation, and apoptosis: Different roles for Protein S. Blood, 103(4), 1192–1201. PMID: 14551144
Saposnik B., et al. (2013). Low Protein S levels and thrombotic risk: Clinical and genetic correlations. American Journal of Clinical Pathology, 139(2), 178–184. PMID: 23355245

Protein S activity, Plasma Price in Pune

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Protein S activity, Plasma with a clear pricing structure

The price of Protein S activity, Plasma in Pune is ₹ 4,970

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

What is the Protein S Activity Test used for?

It assesses Protein S function to help detect the risk of abnormal clot formation.

Who should get this test done?

People with unexplained blood clots, DVT, or a family history of thrombosis should take this test.

Do I need to fast before this test?

No fasting is needed for this test.

What does a low Protein S activity result mean?

It suggests Protein S deficiency, increasing the risk of thrombosis or clotting issues.

Can medications affect Protein S levels?

Yes, certain anticoagulants, contraceptives, or hormone therapies can influence results.

Is home sample collection available for this test?

No, this test requires lab-based sample handling due to strict temperature control needs.

When will I receive my report?

Reports are available the next day once your sample reaches the lab.

How it Works?

All our phlebotomists are vaccinated

At Metropolis Healthcare, your well-being is our top priority. Rest assured, all our skilled phlebotomists are vaccinated, ensuring a safe and secure experience for you. Our team upholds the highest healthcare standards, and your health is in capable hands. Your safety is non-negotiable, and at Metropolis, we take every measure to guarantee it.

Our Phlebotomists maintain a high standard of safety precautions

Our dedicated team of phlebotomists prioritises your safety before anything else. They implement stringent safety measures to guarantee your well-being during their visit.

Strictly adhering to aseptic techniques, our phlebotomists maintain a sterile environment with thorough sanitization and the use of gloves, masks and face shields. Needles are disposed of with utmost care, following rigorous guidelines to minimise any potential risks. We leave no room for compromise when it comes to personal protective equipment (PPE), ensuring both you and our staff are well protected.

Our phlebotomists collect samples safely

The phlebotomists at Metropolis Healthcare are proficient in safe sample collection. They skillfully and gently draw blood, minimizing any discomfort you may feel. We prioritize your safety by using sterile, single-use needles and barcoded vials to completely eliminate any risk of cross-contamination. Our collection area is carefully sanitized before, during, and after your sample collection.

Samples are processed at high-tech facilities

Metropolis Healthcare takes pride in its state-of-the-art facilities, where your samples are thoroughly processed. Our labs are equipped with cutting-edge machinery with advanced technology, eliminating chances of human error. From the moment your sample arrives at our facility, it undergoes an automated process.

Your samples are stored in clean and secure facilities

We leave no room for compromise when it comes to the storage of your samples. Our storage facilities are regularly cleaned and disinfected, upholding the highest standards of healthcare safety.

Temperature-controlled environments and cooling facilities ensure that your samples remain fresh and the results produced are accurate. Our cutting-edge security measures prevent unauthorized access, guaranteeing the confidentiality of your health data.

Metropolis provides accurate digital reports

Our advanced sample processing machines not only deliver swift results to you but also generate precise digital reports. We provide conclusive diagnoses through meticulous re-checks and repeat specimen analyses, if required, at no extra cost, adding an extra layer of accuracy and dependability. This unique approach sets us apart, earning the trust of top doctors and hospitals across the country.

Your health is our priority, and we spare no effort in our commitment to providing you with the most accurate insights you can rely on.

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Why Metropolis?

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.