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Lupus Anticoagulants (LAC) Profile

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LAC Test Overview

Lupus anticoagulants are antibodies that interfere with normal blood clotting function and increase the risk of developing blood clots in veins and arteries. These are produced by the immune system spontaneously due to certain medications, infections, or autoimmune diseases such as lupus erythematosus. Infections like syphilis and hepatitis C can increase the likelihood of acquiring lupus anticoagulants. The Lupus Anticoagulants (LAC) profile is a diagnostic test used to detect the presence of lupus anticoagulant antibodies in the blood. Lupus anticoagulants are autoantibodies that can interfere with the normal clotting process, leading to an increased risk of abnormal blood clot formation (thrombosis) or prolonged bleeding. The LAC profile involves a series of laboratory tests, including the activated partial thromboplastin time (aPTT), dilute Russell's viper venom time (dRVVT), and a mixing study. These tests help assess the presence and functional properties of lupus anticoagulant antibodies. A positive LAC profile indicates the presence of lupus anticoagulant and may be associated with conditions such as antiphospholipid syndrome (APS) or systemic lupus erythematosus (SLE). The LAC profile is crucial in the diagnosis and management of these autoimmune disorders, guiding appropriate treatment and preventive measures to reduce the risk of thrombotic events or excessive bleeding.

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Lupus Anticoagulants (LAC) Profile Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Lupus Anticoagulants (LAC) Profile with a clear pricing structure.

The Lupus Anticoagulants (LAC) Profile Price in Mumbai is ₹ 2,200 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The Lupus Anticoagulants (LAC) Profile measures the presence of lupus anticoagulant antibodies in the blood.

The Lupus Anticoagulants (LAC) Profile is done for several reasons, such as: • To diagnose conditions associated with abnormal blood clotting • To monitor the effectiveness of treatment for these conditions • To assess the risk of developing blood clots • To evaluate unexplained recurrent miscarriages or fetal loss • To investigate prolonged APTT (Activated Partial Thromboplastin Time)

Your doctor may recommend the Lupus Anticoagulants (LAC) Profile if you have • An unexplained history of recurrent miscarriages or fetal loss. • Symptoms suggestive of abnormal blood clotting, such as deep vein thrombosis or pulmonary embolism. • A family history of abnormal blood clotting disorders. • A prolonged APTT test result. • Autoimmune diseases like systemic lupus erythematosus (SLE).

Abnormal results may indicate the presence of lupus anticoagulant antibodies and an increased risk of blood clotting disorders.

During the Lupus Anticoagulants (LAC) Profile: • A blood sample will be collected from a vein in your arm. • The sample will be sent to the laboratory for testing.

Before the Lupus Anticoagulants (LAC) Profile: • Inform your doctor about any medications you are taking, as certain drugs can interfere with test results. • Follow any instructions given by your doctor regarding fasting or dietary restrictions. • Wear loose-fitting clothing that allows easy access to your arm for sample collection. Please reach out to your healthcare provider for any specific requirements.

Other tests that may be ordered alongside the Lupus Anticoagulants (LAC) Profile include: • APTT (Activated Partial Thromboplastin Time): Measures factors involved in blood clotting • PT/INR (Prothrombin Time/International Normalised Ratio): Measures the time it takes for blood to clot • Thrombophilia Panel: Evaluates genetic and acquired risk factors for abnormal blood clotting • Mixing Studies: Used to determine the cause of prolonged clotting times

Lupus Anticoagulant Screen and Confirmation test

Antiphospholipid syndrome is an autoimmune disorder characterised by the presence of specific antibodies that increase the risk of blood clot formation. It can lead to complications such as deep vein thrombosis, pulmonary embolism, stroke, and recurrent miscarriages. The Lupus Anticoagulants (LAC) Profile is used to diagnose this condition as well.

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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